Department of Surgery
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The modulation of hepatic injury and heat shock expression by inhibition of inducible nitric oxide synthase after hemorrhagic shock.
Shock (Augusta, Ga.) Jan, 2002 | Pubmed ID: 11795663
Hypoxia inhibition of apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
Biochemical and biophysical research communications Feb, 2002 | Pubmed ID: 11829475
Potentiation of nitric oxide-induced apoptosis in p53-/- vascular smooth muscle cells.
American journal of physiology. Cell physiology Mar, 2002 | Pubmed ID: 11832348
TRISS unexpected survivors: an outdated standard?
The Journal of trauma Feb, 2002 | Pubmed ID: 11834980
A nitric oxide scavenger protects against pulmonary inflammation following hemorrhagic shock.
Shock (Augusta, Ga.) Feb, 2002 | Pubmed ID: 11837796
IFN-gamma inhibition of TRAIL-induced IAP-2 upregulation, a possible mechanism of IFN-gamma-enhanced TRAIL-induced apoptosis.
Biochemical and biophysical research communications Feb, 2002 | Pubmed ID: 11846395
Role of galectin-3 in breast cancer metastasis: involvement of nitric oxide.
The American journal of pathology Mar, 2002 | Pubmed ID: 11891203
Inducible nitric oxide synthase: from cloning to therapeutic applications.
World journal of surgery Jul, 2002 | Pubmed ID: 11960209
Requirements for NF-kappaB activation in hemorrhagic shock.
Archives of orthopaedic and trauma surgery Feb, 2002 | Pubmed ID: 11995880
Signaling and function of caspase and c-jun N-terminal kinase in cisplatin-induced apoptosis.
Molecules and cells Apr, 2002 | Pubmed ID: 12018840
Role of toll-like receptors in changes in gene expression and NF-kappa B activation in mouse hepatocytes stimulated with lipopolysaccharide.
Infection and immunity Jul, 2002 | Pubmed ID: 12065483
Mechanisms of hepatoprotection by nitric oxide.
Annals of the New York Academy of Sciences May, 2002 | Pubmed ID: 12076992
Peroxisomal localization of inducible nitric oxide synthase in hepatocytes.
Hepatology (Baltimore, Md.) Jul, 2002 | Pubmed ID: 12085352
Hepatocyte Fas-associating death domain protein/mediator of receptor-induced toxicity (FADD/MORT1) levels increase in response to pro-apoptotic stimuli.
The Journal of biological chemistry Oct, 2002 | Pubmed ID: 12167637
A brief episode of hypotension increases mortality in critically ill trauma patients.
The Journal of trauma Aug, 2002 | Pubmed ID: 12169927
Nitric oxide and wound repair: role of cytokines?
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society Aug, 2002 | Pubmed ID: 12175813
Nitric oxide (NO) pretreatment increases cytokine-induced NO production in cultured rat hepatocytes by suppressing GTP cyclohydrolase I feedback inhibitory protein level and promoting inducible NO synthase dimerization.
The Journal of biological chemistry Dec, 2002 | Pubmed ID: 12359727
A DNA microarray study of nitric oxide-induced genes in mouse hepatocytes: implications for hepatic heme oxygenase-1 expression in ischemia/reperfusion.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society Nov, 2002 | Pubmed ID: 12381414
Maternity policy and practice during surgery residency: how we do it.
Surgery Oct, 2002 | Pubmed ID: 12407353
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury.
Nature medicine Feb, 2003 | Pubmed ID: 12539038
Characterization of the expression of inducible nitric oxide synthase in rat and human liver during hemorrhagic shock.
Shock (Augusta, Ga.) Feb, 2003 | Pubmed ID: 12578118
Ultraviolet irradiation increases FADD protein in apoptotic human keratinocytes.
Biochemical and biophysical research communications Mar, 2003 | Pubmed ID: 12604344
Intra-abdominal activation of a local inflammatory response within the human muscularis externa during laparotomy.
Annals of surgery Mar, 2003 | Pubmed ID: 12616113
Regulation of tissue factor expression in smooth muscle cells with nitric oxide.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter Mar, 2003 | Pubmed ID: 12618706
Overexpression of the human inducible nitric oxide synthase gene enhances radiation-induced apoptosis in colorectal cancer cells via a caspase-dependent mechanism.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society Mar, 2003 | Pubmed ID: 12620375
Heme oxygenase-1: a cellular Hercules.
Hepatology (Baltimore, Md.) Apr, 2003 | Pubmed ID: 12668964
Autologous nitric oxide protects mouse and human keratinocytes from ultraviolet B radiation-induced apoptosis.
American journal of physiology. Cell physiology May, 2003 | Pubmed ID: 12676653
There's NO business like p53 business: nitric oxide regulates phosphorylation of p53 in chronic inflammatory disease.
Cell cycle (Georgetown, Tex.) Mar-Apr, 2003 | Pubmed ID: 12695658
Nitric oxide prevents 6-hydroxydopamine-induced apoptosis in PC12 cells through cGMP-dependent PI3 kinase/Akt activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2003 | Pubmed ID: 12773486
Nitric oxide and wound repair.
The Surgical clinics of North America Jun, 2003 | Pubmed ID: 12822723
Fas-associating death domain protein overexpression induces apoptosis in lung cancer cells.
The Journal of thoracic and cardiovascular surgery Jun, 2003 | Pubmed ID: 12830053
RhoA influences the nuclear localization of extracellular signal-regulated kinases to modulate p21Waf/Cip1 expression.
Circulation Aug, 2003 | Pubmed ID: 12874183
Nitric oxide-mediated inhibition of caspase-dependent T lymphocyte proliferation.
Journal of leukocyte biology Sep, 2003 | Pubmed ID: 12949244
A role for angiotensin II in the activation of extracellular signal-regulated kinases in the liver during hemorrhagic shock.
Shock (Augusta, Ga.) Oct, 2003 | Pubmed ID: 14501944
Role of nitric oxide in liver injury.
Current molecular medicine Sep, 2003 | Pubmed ID: 14527083
Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1.
The Journal of experimental medicine Dec, 2003 | Pubmed ID: 14657222
Selective jejunal manipulation causes postoperative pan-enteric inflammation and dysmotility.
Gastroenterology Jan, 2004 | Pubmed ID: 14699497
Carbon monoxide inhibits T lymphocyte proliferation via caspase-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2004 | Pubmed ID: 14707100
Induced nitric oxide promotes intestinal inflammation following hemorrhagic shock.
American journal of physiology. Gastrointestinal and liver physiology Feb, 2004 | Pubmed ID: 14715517
IRF-1 expression induces apoptosis and inhibits tumor growth in mouse mammary cancer cells in vitro and in vivo.
Oncogene Feb, 2004 | Pubmed ID: 14762441
Blood soluble drag-reducing polymers prevent lethality from hemorrhagic shock in acute animal experiments.
Biorheology , 2004 | Pubmed ID: 14967890
Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity.
Cancer research Feb, 2004 | Pubmed ID: 14973054
'Til cell death do us part: nitric oxide and mechanisms of hepatotoxicity.
Biological chemistry Jan, 2004 | Pubmed ID: 14977041
The Department of Surgery at the School of Medicine at the University Of Pittsburgh, Pittsburgh, Pa.
Archives of surgery (Chicago, Ill. : 1960) May, 2004 | Pubmed ID: 15136344
Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation.
Cancer research Jun, 2004 | Pubmed ID: 15205314
Nitric oxide facilitates cardiomyogenesis in mouse embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2004 | Pubmed ID: 15304656
The secretable form of trimeric TRAIL, a potent inducer of apoptosis.
Biochemical and biophysical research communications Sep, 2004 | Pubmed ID: 15358116
Nitric oxide suppresses inducible nitric oxide synthase expression by inhibiting post-translational modification of IkappaB.
Experimental & molecular medicine Aug, 2004 | Pubmed ID: 15365250
Tissue hypoxia activates JNK in the liver during hemorrhagic shock.
Shock (Augusta, Ga.) Oct, 2004 | Pubmed ID: 15377896
IFN-gamma enhances TRAIL-induced apoptosis through IRF-1.
European journal of biochemistry / FEBS Nov, 2004 | Pubmed ID: 15511228
Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53.
Cancer research Nov, 2004 | Pubmed ID: 15520210
Inflammatory modulation of hepatocyte apoptosis by nitric oxide: in vivo, in vitro, and in silico studies.
Current molecular medicine Nov, 2004 | Pubmed ID: 15579022
Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Feb, 2005 | Pubmed ID: 15643987
Enhanced oxidative stress in iNOS-deficient mice after traumatic brain injury: support for a neuroprotective role of iNOS.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Jun, 2005 | Pubmed ID: 15716856
Application of genome-wide expression analysis to human health and disease.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2005 | Pubmed ID: 15781863
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion.
The Journal of experimental medicine Apr, 2005 | Pubmed ID: 15795240
Induction of IL-6 within the rodent intestinal muscularis after intestinal surgical stress.
Surgery Apr, 2005 | Pubmed ID: 15800492
Hepatocytes enhance effects of lipopolysaccharide on liver nonparenchymal cells through close cell interactions.
Shock (Augusta, Ga.) May, 2005 | Pubmed ID: 15834312
Carbon monoxide prevents multiple organ injury in a model of hemorrhagic shock and resuscitation.
Shock (Augusta, Ga.) Jun, 2005 | Pubmed ID: 15897805
The acute inflammatory response in diverse shock states.
Shock (Augusta, Ga.) Jul, 2005 | Pubmed ID: 15988324
The role of hepatic type 1 plasminogen activator inhibitor (PAI-1) during murine hemorrhagic shock.
Hepatology (Baltimore, Md.) Aug, 2005 | Pubmed ID: 16025510
Biliverdin administration prevents the formation of intimal hyperplasia induced by vascular injury.
Circulation Jul, 2005 | Pubmed ID: 16027253
Glutathione depletion renders rat hepatocytes sensitive to nitric oxide donor-mediated toxicity.
Hepatology (Baltimore, Md.) Sep, 2005 | Pubmed ID: 16116630
Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation.
American journal of physiology. Lung cellular and molecular physiology Apr, 2006 | Pubmed ID: 16272176
Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols.
Journal of the American Chemical Society Nov, 2005 | Pubmed ID: 16277524
Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2005 | Pubmed ID: 16301676
Nitric oxide: a clinical primer.
Critical care medicine Dec, 2005 | Pubmed ID: 16340431
Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2006 | Pubmed ID: 16493066
Toll-like receptor-4 signaling mediates hepatic injury and systemic inflammation in hemorrhagic shock.
Journal of the American College of Surgeons Mar, 2006 | Pubmed ID: 16500244
Carbon monoxide protects hepatocytes from TNF-alpha/Actinomycin D by inhibition of the caspase-8-mediated apoptotic pathway.
Biochemical and biophysical research communications Jun, 2006 | Pubmed ID: 16647044
Systemic inflammation and remote organ damage following bilateral femur fracture requires Toll-like receptor 4.
American journal of physiology. Regulatory, integrative and comparative physiology Oct, 2006 | Pubmed ID: 16675630
The role of RAGE in the pathogenesis of intestinal barrier dysfunction after hemorrhagic shock.
American journal of physiology. Gastrointestinal and liver physiology Oct, 2006 | Pubmed ID: 16751175
Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2006 | Pubmed ID: 16751357
Leukocyte-derived inducible nitric oxide synthase mediates murine postoperative ileus.
Annals of surgery Aug, 2006 | Pubmed ID: 16858184
Low-dose carbon monoxide inhalation prevents ischemia/reperfusion injury of transplanted rat lung grafts.
Surgery Aug, 2006 | Pubmed ID: 16904967
Carbon monoxide reverses established pulmonary hypertension.
The Journal of experimental medicine Sep, 2006 | Pubmed ID: 16908624
In silico models of acute inflammation in animals.
Shock (Augusta, Ga.) Sep, 2006 | Pubmed ID: 16912648
Ischemic preconditioning of the murine liver protects through the Akt kinase pathway.
Hepatology (Baltimore, Md.) Sep, 2006 | Pubmed ID: 16941697
Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock.
Molecular medicine (Cambridge, Mass.) Apr-Jun, 2006 | Pubmed ID: 16953558
In silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice.
Molecular medicine (Cambridge, Mass.) Apr-Jun, 2006 | Pubmed ID: 16953560
Emerging paradigm: toll-like receptor 4-sentinel for the detection of tissue damage.
Shock (Augusta, Ga.) Nov, 2006 | Pubmed ID: 17047512
Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury.
Journal of leukocyte biology Jan, 2007 | Pubmed ID: 17062605
The role of initial trauma in the host's response to injury and hemorrhage: insights from a correlation of mathematical simulations and hepatic transcriptomic analysis.
Shock (Augusta, Ga.) Dec, 2006 | Pubmed ID: 17117135
Early growth response 1 mediates the systemic and hepatic inflammatory response initiated by hemorrhagic shock.
Shock (Augusta, Ga.) Feb, 2007 | Pubmed ID: 17224790
Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Apr, 2007 | Pubmed ID: 17264172
Targeting CD47: NO limit on therapeutic potential.
Circulation research Mar, 2007 | Pubmed ID: 17363705
Making progress in an enlightened era: opportunities and obstacles.
Surgical infections Feb, 2007 | Pubmed ID: 17381393
Neuronal NOS-mediated nitration and inactivation of manganese superoxide dismutase in brain after experimental and human brain injury.
Journal of neurochemistry Apr, 2007 | Pubmed ID: 17394464
A novel inhibitory peptide of Toll-like receptor signaling limits lipopolysaccharide-induced production of inflammatory mediators and enhances survival in mice.
Shock (Augusta, Ga.) Apr, 2007 | Pubmed ID: 17414417
Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling.
Journal of immunology (Baltimore, Md. : 1950) May, 2007 | Pubmed ID: 17475888
Masquerader: high mobility group box-1 and cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2007 | Pubmed ID: 17504981
Neutrophil NAD(P)H oxidase is required for hemorrhagic shock-enhanced TLR2 up-regulation in alveolar macrophages in response to LPS.
Shock (Augusta, Ga.) Aug, 2007 | Pubmed ID: 17515854
Hypoxia activates c-Jun N-terminal kinase via Rac1-dependent reactive oxygen species production in hepatocytes.
Shock (Augusta, Ga.) Sep, 2007 | Pubmed ID: 17545941
Thioredoxin catalyzes the denitrosation of low-molecular mass and protein S-nitrosothiols.
Biochemistry Jul, 2007 | Pubmed ID: 17580965
Systemic inflammation and remote organ injury following trauma require HMGB1.
American journal of physiology. Regulatory, integrative and comparative physiology Oct, 2007 | Pubmed ID: 17652366
Systemic inflammation and end organ damage following trauma involves functional TLR4 signaling in both bone marrow-derived cells and parenchymal cells.
Journal of leukocyte biology Jan, 2008 | Pubmed ID: 17925504
Increased interactive format for Morbidity & Mortality conference improves educational value and enhances confidence.
Journal of surgical education Sep-Oct, 2007 | Pubmed ID: 17961883
The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity.
Immunological reviews Dec, 2007 | Pubmed ID: 17979840
HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling.
The Journal of experimental medicine Nov, 2007 | Pubmed ID: 17984303
FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells.
Cardiovascular research Feb, 2008 | Pubmed ID: 18006431
Early events in the recognition of danger signals after tissue injury.
Journal of leukocyte biology Mar, 2008 | Pubmed ID: 18032691
Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
Transplantation Nov, 2007 | Pubmed ID: 18049113
Galantamine and carbon monoxide protect brain microvascular endothelial cells by heme oxygenase-1 induction.
Biochemical and biophysical research communications Mar, 2008 | Pubmed ID: 18174021
Carbon monoxide decreases the level of iNOS protein and active dimer in IL-1beta-stimulated hepatocytes.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society Jun, 2008 | Pubmed ID: 18313411
Protective effect of p53 in vascular smooth muscle cells against nitric oxide-induced apoptosis is mediated by up-regulation of heme oxygenase-2.
BMB reports Feb, 2008 | Pubmed ID: 18315954
Male gender is associated with excessive IL-6 expression following severe injury.
The Journal of trauma Mar, 2008 | Pubmed ID: 18332795
Application of heme oxygenase-1, carbon monoxide and biliverdin for the prevention of intestinal ischemia/reperfusion injury.
Journal of clinical biochemistry and nutrition Mar, 2008 | Pubmed ID: 18385824
HMGB1: endogenous danger signaling.
Molecular medicine (Cambridge, Mass.) Jul-Aug, 2008 | Pubmed ID: 18431461
Local exposure of bone components to injured soft tissue induces Toll-like receptor 4-dependent systemic inflammation with acute lung injury.
Shock (Augusta, Ga.) Dec, 2008 | Pubmed ID: 18461022
Carbon monoxide activates NF-kappaB via ROS generation and Akt pathways to protect against cell death of hepatocytes.
American journal of physiology. Gastrointestinal and liver physiology Jul, 2008 | Pubmed ID: 18497334
Computational insights on the competing effects of nitric oxide in regulating apoptosis.
PloS one , 2008 | Pubmed ID: 18509469
Changes in FADD levels, distribution, and phosphorylation in TNFalpha-induced apoptosis in hepatocytes is caspase-3, caspase-8 and BID dependent.
Apoptosis : an international journal on programmed cell death Aug, 2008 | Pubmed ID: 18543108
Detection and measurement for the modification and inactivation of caspase by nitrosative stress in vitro and in vivo.
Methods in enzymology , 2008 | Pubmed ID: 18554542
Patterns of cytokine release and evolution of remote organ dysfunction after bilateral femur fracture.
Shock (Augusta, Ga.) Jul, 2008 | Pubmed ID: 18562923
The role of fracture-associated soft tissue injury in the induction of systemic inflammation and remote organ dysfunction after bilateral femur fracture.
Journal of orthopaedic trauma Jul, 2008 | Pubmed ID: 18594302
Preconditioning with high mobility group box 1 (HMGB1) induces lipopolysaccharide (LPS) tolerance.
Journal of leukocyte biology Nov, 2008 | Pubmed ID: 18687905
Beta2-integrin-induced p38 MAPK activation is a key mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes.
The Journal of biological chemistry Oct, 2008 | Pubmed ID: 18701460
Calcium/calmodulin-dependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2008 | Pubmed ID: 18802105
Parenteral calcium for intensive care unit patients.
Cochrane database of systematic reviews (Online) , 2008 | Pubmed ID: 18843706
An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion.
The Journal of trauma Nov, 2008 | Pubmed ID: 19001962
Interacting neuroendocrine and innate and acquired immune pathways regulate neutrophil mobilization from bone marrow following hemorrhagic shock.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2009 | Pubmed ID: 19109190
Studies toward the analysis of S-nitrosoproteins.
Organic & biomolecular chemistry Jan, 2009 | Pubmed ID: 19109666
Expression and subcellular localization of BNIP3 in hypoxic hepatocytes and liver stress.
American journal of physiology. Gastrointestinal and liver physiology Mar, 2009 | Pubmed ID: 19147804
Therapeutic antioxidant medical gas.
Journal of clinical biochemistry and nutrition Jan, 2009 | Pubmed ID: 19177183
Possible novel therapy for malignant gliomas with secretable trimeric TRAIL.
PloS one , 2009 | Pubmed ID: 19229339
Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism.
Hepatology (Baltimore, Md.) May, 2009 | Pubmed ID: 19296467
Mechanisms of Toll-like receptor 4 (TLR4)-mediated inflammation after cold ischemia/reperfusion in the heart.
Transplantation May, 2009 | Pubmed ID: 19461481
Innate immune mechanisms in ischemia/reperfusion.
Frontiers in bioscience (Elite edition) , 2009 | Pubmed ID: 19482628
Low-dose cisplatin administration in murine cecal ligation and puncture prevents the systemic release of HMGB1 and attenuates lethality.
Journal of leukocyte biology Sep, 2009 | Pubmed ID: 19487305
Cisplatin prevents high mobility group box 1 release and is protective in a murine model of hepatic ischemia/reperfusion injury.
Hepatology (Baltimore, Md.) Aug, 2009 | Pubmed ID: 19492424
Preactivation of NKT cells with alpha-GalCer protects against hepatic ischemia-reperfusion injury in mouse by a mechanism involving IL-13 and adenosine A2A receptor.
American journal of physiology. Gastrointestinal and liver physiology Aug, 2009 | Pubmed ID: 19556359
Activation of latent transforming growth factor-beta1 by nitric oxide in macrophages: role of soluble guanylate cyclase and MAP kinases.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society Jul-Aug, 2009 | Pubmed ID: 19614923
Orally administered nitrite attenuates cardiac allograft rejection in rats.
Surgery Aug, 2009 | Pubmed ID: 19628069
Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome.
The Journal of trauma Aug, 2009 | Pubmed ID: 19667872
Preinjury statin use is associated with a higher risk of multiple organ failure after injury: a propensity score adjusted analysis.
The Journal of trauma Sep, 2009 | Pubmed ID: 19741387
The nitric oxide donor S-nitrosoglutathione reduces apoptotic primary liver cell loss in a three-dimensional perfusion bioreactor culture model developed for liver support.
Tissue engineering. Part A Mar, 2010 | Pubmed ID: 19814591
Nitric oxide and dihydrolipoic acid modulate the activity of caspase 3 in HepG2 cells.
FEBS letters Nov, 2009 | Pubmed ID: 19822150
Hemorrhagic shock augments lung endothelial cell activation: role of temporal alterations of TLR4 and TLR2.
American journal of physiology. Regulatory, integrative and comparative physiology Dec, 2009 | Pubmed ID: 19828841
Oral hydrogen water prevents chronic allograft nephropathy in rats.
Kidney international Jan, 2010 | Pubmed ID: 19907413
Nitric oxide and thioredoxin type 1 modulate the activity of caspase 8 in HepG2 cells.
Biochemical and biophysical research communications Jan, 2010 | Pubmed ID: 20005201
An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage.
PloS one , 2009 | Pubmed ID: 20027315
Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation May, 2010 | Pubmed ID: 20036162
Linking oxidative stress to inflammation: Toll-like receptors.
Free radical biology & medicine May, 2010 | Pubmed ID: 20083193
Pivotal advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through distinct but overlapping mechanisms.
Journal of leukocyte biology Oct, 2010 | Pubmed ID: 20413727
Hemorrhagic shock activates lung endothelial reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase via neutrophil NADPH oxidase.
American journal of respiratory cell and molecular biology Mar, 2011 | Pubmed ID: 20418360
Analysis of factorial time-course microarrays with application to a clinical study of burn injury.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2010 | Pubmed ID: 20479259
Dominant role of the MyD88-dependent signaling pathway in mediating early endotoxin-induced murine ileus.
American journal of physiology. Gastrointestinal and liver physiology Aug, 2010 | Pubmed ID: 20508155
Delay to therapeutic interventional radiology postinjury: time is of the essence.
The Journal of trauma Jun, 2010 | Pubmed ID: 20539172
Systemic inflammation and liver injury following hemorrhagic shock and peripheral tissue trauma involve functional TLR9 signaling on bone marrow-derived cells and parenchymal cells.
Shock (Augusta, Ga.) Feb, 2011 | Pubmed ID: 20577143
Hepatocytes express functional NOD1 and NOD2 receptors: a role for NOD1 in hepatocyte CC and CXC chemokine production.
Journal of hepatology Oct, 2010 | Pubmed ID: 20615568
A critical role for IFN regulatory factor 1 in NKT cell-mediated liver injury induced by alpha-galactosylceramide.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2010 | Pubmed ID: 20624945
Superior myocardial preservation with HTK solution over Celsior in rat hearts with prolonged cold ischemia.
Surgery Aug, 2010 | Pubmed ID: 20627336
Toll-like receptors and myocardial ischemia/reperfusion, inflammation, and injury.
Current cardiology reviews Aug, 2009 | Pubmed ID: 20676278
Role of hemorrhage in the induction of systemic inflammation and remote organ damage: analysis of combined pseudo-fracture and hemorrhagic shock.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Feb, 2011 | Pubmed ID: 20690183
Complement factor 3 deficiency attenuates hemorrhagic shock-related hepatic injury and systemic inflammatory response syndrome.
American journal of physiology. Regulatory, integrative and comparative physiology Nov, 2010 | Pubmed ID: 20702808
Incidental radiographic findings after injury: dedicated attention results in improved capture, documentation, and management.
Surgery Oct, 2010 | Pubmed ID: 20705305
Toll-like receptors in hepatic ischemia/reperfusion and transplantation.
Gastroenterology research and practice , 2010 | Pubmed ID: 20811615
Differential regulation by fucoidan of IFN-γ-induced NO production in glial cells and macrophages.
Journal of cellular biochemistry Dec, 2010 | Pubmed ID: 20830678
Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight.
Medical hypotheses Jan, 2011 | Pubmed ID: 20851533
Ex vivo carbon monoxide delivery inhibits intimal hyperplasia in arterialized vein grafts.
Cardiovascular research Feb, 2011 | Pubmed ID: 20851811
Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine liver ischemia-reperfusion injury.
Shock (Augusta, Ga.) Mar, 2011 | Pubmed ID: 20856174
High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activity.
The Journal of biological chemistry Dec, 2010 | Pubmed ID: 20937823
Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats.
Transplantation Dec, 2010 | Pubmed ID: 21048533
TNF/TNF receptor 1-mediated apoptosis in hepatocytes.
Advances in experimental medicine and biology , 2011 | Pubmed ID: 21153368
Hydrogen inhalation ameliorates ventilator-induced lung injury.
Critical care (London, England) , 2010 | Pubmed ID: 21184683
DNA attenuates enterocyte Toll-like receptor 4-mediated intestinal mucosal injury after remote trauma.
American journal of physiology. Gastrointestinal and liver physiology May, 2011 | Pubmed ID: 21233273
Models of lower extremity damage in mice: time course of organ damage and immune response.
The Journal of surgical research Apr, 2011 | Pubmed ID: 21276982
Over reliance on computed tomography imaging in patients with severe abdominal injury: is the delay worth the risk?
The Journal of trauma Feb, 2011 | Pubmed ID: 21307722
Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury.
The Journal of trauma Feb, 2011 | Pubmed ID: 21307724
Histidine-tryptophan-ketoglutarate or celsior: which is more suitable for cold preservation for cardiac grafts from older donors?
The Annals of thoracic surgery Mar, 2011 | Pubmed ID: 21352993
Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation.
Biochemical and biophysical research communications May, 2011 | Pubmed ID: 21473852
Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1α in mouse hepatocytes.
Shock (Augusta, Ga.) Aug, 2011 | Pubmed ID: 21558981
A dynamic view of trauma/hemorrhage-induced inflammation in mice: principal drivers and networks.
PloS one , 2011 | Pubmed ID: 21573002
High-mobility group box 1 is essential for mitochondrial quality control.
Cell metabolism Jun, 2011 | Pubmed ID: 21641551
Caspase-1 is hepatoprotective during trauma and hemorrhagic shock by reducing liver injury and inflammation.
Molecular medicine (Cambridge, Mass.) Sep-Oct, 2011 | Pubmed ID: 21666957
Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice.
Hepatology (Baltimore, Md.) Sep, 2011 | Pubmed ID: 21721026
Characterization of DISC formation and TNFR1 translocation to mitochondria in TNF-α-treated hepatocytes.
The American journal of pathology Sep, 2011 | Pubmed ID: 21741934
Toll-like receptor signaling in liver diseases.
Gastroenterology research and practice , 2010 | Pubmed ID: 21789039
Sepsis: Something old, something new, and a systems view.
Journal of critical care Jul, 2011 | Pubmed ID: 21798705
The effect of donor treatment with hydrogen on lung allograft function in rats.
Surgery Aug, 2011 | Pubmed ID: 21801961
Early lower extremity fracture fixation and the risk of early pulmonary embolus: filter before fixation?
The Journal of trauma Jun, 2011 | Pubmed ID: 21817975
Transcriptomic response of murine liver to severe injury and hemorrhagic shock: a dual-platform microarray analysis.
Physiological genomics Oct, 2011 | Pubmed ID: 21828244
Mast cells play a critical role in the systemic inflammatory response and end-organ injury resulting from trauma.
Journal of the American College of Surgeons Nov, 2011 | Pubmed ID: 21920785
Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2011 | Pubmed ID: 21940680
Hydrogen-enriched preservation protects the isogeneic intestinal graft and amends recipient gastric function during transplantation.
Transplantation Nov, 2011 | Pubmed ID: 21956195
Assessment of platelet transfusion for reversal of aspirin after traumatic brain injury.
Surgery Oct, 2011 | Pubmed ID: 22000198
Interferon Regulatory Factor-1 Regulates the Autophagic Response in LPS Stimulated Macrophages through Nitric Oxide.
Molecular medicine (Cambridge, Mass.) Nov, 2011 | Pubmed ID: 22105605
A genomic storm in critically injured humans.
The Journal of experimental medicine Dec, 2011 | Pubmed ID: 22110166
Complement C3 deficiency attenuates chronic hypoxia-induced pulmonary hypertension in mice.
PloS one , 2011 | Pubmed ID: 22194859
Splenocyte Apoptosis and Autophagy is Mediated by Interferon Regulatory Factor-1 During Murine Endotoxemia.
Shock (Augusta, Ga.) Jan, 2012 | Pubmed ID: 22266972
Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.
Cardiovascular research Jan, 2012 | Pubmed ID: 22287575
Role of Macrophages in Mobilization of Hematopoietic Progenitor Cells From Bone Marrow After Hemorrhagic Shock.
Shock (Augusta, Ga.) Jan, 2012 | Pubmed ID: 22293600
Evolving role of endovascular techniques for traumatic vascular injury: A changing landscape?
The Journal of trauma Jan, 2012 | Pubmed ID: 22310114
Changes in massive transfusion over time: An early shift in the right direction?
The Journal of trauma Jan, 2012 | Pubmed ID: 22310123
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