James Tunnell

Methodology for estimation of time-dependent surface heat flux due to cryogen spray cooling.

Optimum pulse duration and radiant exposure for vascular laser therapy of dark port-wine skin: a theoretical study.

Methodology for characterizing heat removal mechanism in human skin during cryogen spray cooling.

Effects of cryogen spray cooling and high radiant exposures on selective vascular injury during laser irradiation of human skin.

Thermal response of human skin epidermis to 595-nm laser irradiation at high incident dosages and long pulse durations in conjunction with cryogen spray cooling: an ex-vivo study.

Effects of droplet velocity, diameter, and film height on heat removal during cryogen spray cooling.

Assessing epithelial cell nuclear morphology by using azimuthal light scattering spectroscopy.

Modulation of in vivo tumor radiation response via gold nanoshell-mediated vascular-focused hyperthermia: characterizing an integrated antihypoxic and localized vascular disrupting targeting strategy.

Two-photon-induced photoluminescence imaging of tumors using near-infrared excited gold nanoshells.

Lookup table-based inverse model for determining optical properties of turbid media.

Re-evaluation of model-based light-scattering spectroscopy for tissue spectroscopy.

Near-infrared narrow-band imaging of gold/silica nanoshells in tumors.

Design and validation of a clinical instrument for spectral diagnosis of cutaneous malignancy.

Temperature-induced unfolding of epidermal growth factor (EGF): insight from molecular dynamics simulation.

Lookup-table method for imaging optical properties with structured illumination beyond the diffusion theory regime.

Experimental validation of the effects of microvasculature pigment packaging on in vivo diffuse reflectance spectroscopy.

MEMS scanner enabled real-time depth sensitive hyperspectral imaging of biological tissue.

Pilot clinical study for quantitative spectral diagnosis of non-melanoma skin cancer.

Variation of fluorescence in tissue with temperature.

Probe pressure effects on human skin diffuse reflectance and fluorescence spectroscopy measurements.

Intra-organ Biodistribution of Gold Nanoparticles Using Intrinsic Two-photon Induced Photoluminescence.

Rapid and accurate determination of tissue optical properties using least-squares support vector machines.

Copper selenide nanocrystals for photothermal therapy.

Changes in morphology and optical properties of sclera and choroidal layers due to hyperosmotic agent.

Micro-patterned drug delivery device for light-activated drug release.

Development of a noncontact diffuse optical spectroscopy probe for measuring tissue optical properties.

Narrow band imaging of squamous cell carcinoma tumors using topically delivered anti-EGFR antibody conjugated gold nanorods.

Effects of mechanical indentation on diffuse reflectance spectra, light transmission, and intrinsic optical properties in ex vivo porcine skin.

In vivo tumor targeting of gold nanoparticles: effect of particle type and dosing strategy.

Performance of a lookup table-based approach for measuring tissue optical properties with diffuse optical spectroscopy.

Nanoparticle-mediated photothermal therapy: a comparative study of heating for different particle types.

Segmentation of diffuse reflectance hyperspectral datasets with noise for detection of Melanoma.

Monte Carlo lookup table-based inverse model for extracting optical properties from tissue-simulating phantoms using diffuse reflectance spectroscopy.

Attenuation-corrected fluorescence extraction for image-guided surgery in spatial frequency domain.

Verification of a two-layer inverse Monte Carlo absorption model using multiple source-detector separation diffuse reflectance spectroscopy.

Advances in optics for biotechnology, medicine and surgery.

Handheld Diffuse Reflectance Spectral Imaging (DRSi) for in-vivo characterization of skin.

Design and characterization of a novel multimodal fiber-optic probe and spectroscopy system for skin cancer applications.

Real-time absorption reduced surface fluorescence imaging.

Effect of probe geometry and optical properties on the sampling depth for diffuse reflectance spectroscopy.

Clinical study of noninvasive in vivo melanoma and nonmelanoma skin cancers using multimodal spectral diagnosis.

Impact of one-layer assumption on diffuse reflectance spectroscopy of skin.

Polarized light spatial frequency domain imaging for non-destructive quantification of soft tissue fibrous structures.