Kun Huang

[Construction of a set of secreting expression vectors for Saccharomyces cerevisiea].

RNA-dependent RNA polymerase gene sequence from foot-and-mouth disease virus in Hong Kong.

Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor.

Cloning, expression and identification of a new trehalose synthase gene from Thermobifida fusca genome.

How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.

Why zinc fingers prefer zinc: ligand-field symmetry and the hidden thermodynamics of metal ion selectivity.

Solvation and the hidden thermodynamics of a zinc finger probed by nonstandard repair of a protein crevice.

Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins.

Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues.

Neuroligins mediate excitatory and inhibitory synapse formation: involvement of PSD-95 and neurexin-1beta in neuroligin-induced synaptic specificity.

Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin Wakayama.

Modulation of neuronal protein trafficking and function by palmitoylation.

Proinsulin is refractory to protein fibrillation: topological protection of a precursor protein from cross-beta assembly.

Preparation of highly conductive, self-assembled gold/polyaniline nanocables and polyaniline nanotubes.

Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function.

Disparities in analgesia and opioid prescribing practices for patients with musculoskeletal pain in the emergency department.

[Smoking and subjective life qualities in middle school students].

[Impact of childhood abuses on the psychology and behaviors regarding harmful dietary pattern in adolescents].

Structure-specific effects of protein topology on cross-beta assembly: studies of insulin fibrillation.

Highly enantioselective alpha-aminoxylation of aldehydes and ketones in ionic liquids.

Alterations in cerebral potentials evoked by rectal distention and drinking ice water in patients with irritable bowel syndrome.

Multiscale hybrid linear models for lossy image representation.

Rb is critical in a mammalian tissue stem cell population.

[Correlation between psychopathological symptoms, coping style in adolescent and childhood repeated physical, emotional maltreatment].

Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy.

Virtual mouse placenta: tissue layer segmentation.

Determinants of variation in analgesic and opioid prescribing practice in an emergency department.

Asymmetric synthesis of primary amines via the spiroborate-catalyzed borane reduction of oxime ethers.

The A-chain of insulin contacts the insert domain of the insulin receptor. Photo-cross-linking and mutagenesis of a diabetes-related crevice.

Detection and visualization of surface-pockets to enable phenotyping studies.

Physical activity might not be the protective factor for health risk behaviours and psychopathological symptoms in adolescents.

[Psychological well-being among adolescents of parents living with AIDS or HIV].

The expression of interleukin-22 and S100A7, A8, A9 mRNA in patients with psoriasis vulgaris.

Orthogonal sample design scheme for two-dimensional synchronous spectroscopy and its application in probing intermolecular interactions.

Paralemmin-1, a modulator of filopodia induction is required for spine maturation.

Design of an active ultrastable single-chain insulin analog: synthesis, structure, and therapeutic implications.

An indicator of cancer: downregulation of monoamine oxidase-A in multiple organs and species.

[Study on the relations between psycho-behaviors and weight control in adolescents].

Highly enantioselective borane reduction of heteroaryl and heterocyclic ketoxime ethers catalyzed by novel spiroborate ester derived from diphenylvalinol: application to the synthesis of nicotine analogues.

Reconstruction of cellular biological structures from optical microscopy data.

The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition.

An imaging workflow for characterizing phenotypical change in large histological mouse model datasets.

[Studies on coordination and hydrogen bond intermolecular interaction using 1D & 2D FTIR spectroscopy].

A practical and efficient route for the highly enantioselective synthesis of mexiletine analogues and novel beta-thiophenoxy and pyridyl ethers.

Tensor classification of N-point correlation function features for histology tissue segmentation.

Robust 3D reconstruction and identification of dendritic spines from optical microscopy imaging.

ErbB4-neuregulin signaling modulates synapse development and dendritic arborization through distinct mechanisms.

A 90-day toxicology study of transgenic lysine-rich maize grain (Y642) in Sprague-Dawley rats.

Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation.

[Formation of W/O microemulsions in TBP-Pd(II)-HCl extraction system and spectroscopic research on the evolution of solution aggregation structure].

New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.

Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity.

Decoding the cryptic active conformation of a protein by synthetic photoscanning: insulin inserts a detachable arm between receptor domains.

Enhancing the activity of a protein by stereospecific unfolding: conformational life cycle of insulin and its evolutionary origins.

TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia.

Well-defined organic nanotubes from multicomponent bottlebrush copolymers.

Spiroborate ester-mediated asymmetric synthesis of beta-hydroxy ethers and its conversion to highly enantiopure beta-amino ethers.

Feature-based registration of histopathology images with different stains: an application for computerized follicular lymphoma prognosis.

Overexpression of mitogen-activated protein kinase kinase 4 and nuclear factor-kappaB in laryngeal squamous cell carcinoma: a potential indicator for poor prognosis.

Comparative study on ChIP-seq data: normalization and binding pattern characterization.

[Fluorescence spectra and protonation of ofloxacin in strong acidic solutions].

Synthesis of 1,1-[1-naphthyloxy-2-thiophenyl]-2-methylaminomethylcyclopropanes and their evaluation as inhibitors of serotonin, norepinephrine, and dopamine transporters.

Double orthogonal sample design scheme and corresponding basic patterns in two-dimensional correlation spectra for probing subtle spectral variations caused by intermolecular interactions.

A personalized microRNA microarray normalization method using a logistic regression model.

Proliferative effects of Chishao on Schwann cells are FGF-uPA, and ERK- and JNK-dependent.

A new model-based estimation of ellipses for object representation.

Association of ADAM33 gene polymorphisms with COPD in a northeastern Chinese population.

An Achilles' heel in an amyloidogenic protein and its repair: insulin fibrillation and therapeutic design.

An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis.

A New and Efficient Approach to the Synthesis of Nicotine and Anabasine Analogues.

Supramolecular protein engineering: design of zinc-stapled insulin hexamers as a long acting depot.

Dramatic increase of Cesarean deliveries in the midst of health reforms in rural China.

Allergy and inflammatory transcriptome is predominantly negatively correlated with CD133 expression in glioblastoma.

Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists.

Experimental generation of Laguerre-Gaussian beam using digital micromirror device.

Design of DOE for generating a needle of a strong longitudinally polarized field.

Creation of large band gap with anisotropic annular photonic crystal slab structure.

Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins.

Synaptic activity controls dendritic spine morphology by modulating eEF2-dependent BDNF synthesis.

CATALYTIC ENANTIOSELECTIVE BORANE REDUCTION OF BENZYL OXIMES: PREPARATION OF (S)-1-PYRIDIN-3-YL-ETHYLAMINE BIS HYDROCHLORIDE.

[Two-dimensional synchronous correlation spectroscopy for probing fluorescence energy transfer].

Organosoluble polypyrrole nanotubes from core-shell bottlebrush copolymers.

Space-time latent component modeling of geo-referenced health data.

Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease.

SYNTHESIS OF SPIROBORATE ESTERS FROM 1,2-AMINOALCOHOLS, ETHYLENE GLYCOL AND TRIISOPROPYL BORATE: PREPARATION OF (S)-1-(1,3,2-DIOXABOROLAN-2-YLOXY)-3-METHYL-1,1-DIPHENYLBUTAN-2-AMINE.

Ursolic acid inhibits early lesions of diabetic nephropathy.

Low postnatal care rates in two rural counties in Anhui Province, China: perceptions of key stakeholders.

Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression.

Utilisation, contents and costs of prenatal care under a rural health insurance (New Co-operative Medical System) in rural China: lessons from implementation.

Multi-dimensional discovery of biomarker and phenotype complexes.

Using gene co-expression network analysis to predict biomarkers for chronic lymphocytic leukemia.

RNA polymerase II binding patterns reveal genomic regions involved in microRNA gene regulation.

An efficient organocatalytic method for constructing biaryls through aromatic C-H activation.

Porcine islet amyloid polypeptide fragments are refractory to amyloid formation.

[Preliminary investigation on the formation mechanism of CCL4-water-cetyl trimethyl ammonium bromide (CTAB) gel].

Enabling Data Analysis on High-Throughput Data in Large Data Depository Using Web-Based Analysis Platform - A Case Study on Integrating QUEST with GenePattern in Epigenetics Research.

Borylation of Aryl and Alkenyl Carbamates through Ni-Catalyzed C--O Activation.

[Lamivudine and entecavir significantly improved the prognosis of early-to-mid stage hepatitis B related acute on chronic liver failure].

DNA repair deficiency in a newly identified neurological disease.

Borylation of aryl and alkenyl carbamates through Ni-catalyzed C-O activation.

Andreev and single-particle tunneling spectra of underdoped cuprate superconductors.

Chiral epoxides via borane reduction of 2-haloketones catalyzed by spiroborate ester: application to the synthesis of optically pure 1,2-hydroxy ethers and 1,2-azido alcohols.

Gene network and pathway generation and analysis.

[Mental health and risk behavior of married adult HIV/AIDS subjects derived from paid blood donation in the rural of Anhui Province].

Non-invasive tumor detection in small animals using novel functional Pluronic nanomicelles conjugated with anti-mesothelin antibody.

Transition-metal-catalyzed C-C bond formation through the fixation of carbon dioxide.

Vector-vortex Bessel-Gauss beams and their tightly focusing properties.

Proteins that promote filopodia stability, but not number, lead to more axonal-dendritic contacts.

Transactional Database Transformation and Its Application in Prioritizing Human Disease Genes.

Synthesis of spirocyclic β-keto-lactams: copper catalyzed process.

Comparing multiple ChIP-sequencing experiments.

HYR1-mediated detoxification of reactive oxygen species is required for full virulence in the rice blast fungus.

Photon-number-resolving detection at 1.04 μm via coincidence frequency upconversion.

Completeness and Utility of Interview Data from Proxy Respondents in Prenatal Care Research in Rural China.

De novo synthesis and cellular uptake of organic nanocapsules with tunable surface chemistry.

9-Benzamido-acridinium chloride.

N-(2-Amino-phen-yl)-2-anilinobenzamide.

3,3'-Dimethyl-1,1'-(methyl-enedi-p-phenyl-ene)diimidazolium bis-(hexa-fluoro-phosphate).

Superconcentrated hydrochloric acid.

Arylation of α-pivaloxyl ketones with arylboronic reagents via Ni-catalyzed sp3 C-O activation.

Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.

A multinational study of the influence of health-related quality of life on in-hospital outcome after coronary artery bypass graft surgery.

Enoyl acyl carrier protein reductase inhibitors: a patent review (2006 - 2010).

Inflammatory gene regulatory networks in amnion cells following cytokine stimulation: translational systems approach to modeling human parturition.

KIAA0101 interacts with BRCA1 and regulates centrosome number.

A 90-day safety study in Sprague-Dawley rats fed milk powder containing recombinant human lactoferrin (rhLF) derived from transgenic cloned cattle.

Block copolymer micellization induced microphase mass transfer: partition of Pd(II), Pt(IV) and Rh(III) in three-liquid-phase systems of S201-EOPO-Na2SO4-H2O.

Apelin alleviates diabetes-associated endoplasmic reticulum stress in the pancreas of Akita mice.

Altered palmitoylation and neuropathological deficits in mice lacking HIP14.

A new oncolytic adenoviral vector carrying dual tumor suppressor genes shows potent antitumor effect.

Asynchronous orthogonal sample design scheme for two-dimensional correlation spectroscopy (2D-COS) and its application in probing intermolecular interactions from overlapping infrared (IR) bands.

Maternal thyroid function in the first twenty weeks of pregnancy and subsequent fetal and infant development: a prospective population-based cohort study in China.

Curcumin inhibits neuronal and vascular degeneration in retina after ischemia and reperfusion injury.

Survival and prognostic factors in hepatitis B virus-related acute-on-chronic liver failure.

Realization of a subwavelength focused spot without a longitudinal field component in a solid immersion lens-based system.

Automatic detection of stent struts with thick neointimal growth in intravascular optical coherence tomography image sequences.

Charge and size selective molecular transport by amphiphilic organic nanotubes.

Suppression of plant-generated reactive oxygen species is required for successful infection by the rice blast fungus.

Subwavelength imaging by a graded-index photonic-crystal flat lens in a honeycomb lattice.

Microarray analysis of genes associated with cell surface NIS protein levels in breast cancer.

Non-parametric population analysis of cellular phenotypes.

Periconceptional folic acid supplementation among women attending antenatal clinic in Anhui, China: Data from a population-based cohort study.

Does delivery mode affect women's postpartum quality of life in rural China?

Clonal production and organization of inhibitory interneurons in the neocortex.

Coffee components inhibit amyloid formation of human islet amyloid polypeptide in vitro: possible link between coffee consumption and diabetes mellitus.

3,3'-Dibenzyl-1,1'-[naphthalene-1,4-diylbis(methyl-ene)]di(1H-imidazol-3-ium) bis-(hexa-fluoro-phosphate).

Bis[1-benzyl-3-(4-methyl-phen-yl)imidazol-2-yl-idene]silver(I) hexa-fluorido-phosphate.

1-Benzyl-3-[3-(naphthalen-2-yl-oxy)prop-yl]imidazolium hexa-fluoro-phosphate.

Analyzing ChIP-seq data: preprocessing, normalization, differential identification, and binding pattern characterization.

k-Neighborhood decentralization: A comprehensive solution to index the UMLS for large scale knowledge discovery.

Maternal socio-economic indices for prenatal care research in rural China.

Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets.

Enhance the resolution of photonic crystal negative refraction imaging by metal grating.

Photon correlation in single-photon frequency upconversion.

Integrated analysis identifies a class of androgen-responsive genes regulated by short combinatorial long-range mechanism facilitated by CTCF.

Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide.

Endoplasmic reticulum stress in retinal vascular degeneration: protective role of resveratrol.

Utilization of antenatal ultrasound scan and implications for caesarean section: a cross-sectional study in rural Eastern China.

Atypical E2F repressors and activators coordinate placental development.

Predicting glioblastoma prognosis networks using weighted gene co-expression network analysis on TCGA data.

A signal processing approach for enriched region detection in RNA polymerase II ChIP-seq data.

1-[3-(Anthracen-9-yl)-5-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone.

Low levels of human HIP14 are sufficient to rescue neuropathological, behavioural, and enzymatic defects due to loss of murine HIP14 in Hip14-/- mice.

Dissecting the role of disulfide bonds on the amyloid formation of insulin.

Preferential electrical coupling regulates neocortical lineage-dependent microcircuit assembly.

Safety evaluation of cephalosporins based on utilization and adverse drug events: analysis of two databases in China.

RING finger palmitoylation of the endoplasmic reticulum Gp78 E3 ubiquitin ligase.

Cohort Profile: the China-Anhui Birth Cohort Study.

Developing digital tissue phantoms for hyperspectral imaging of ischemic wounds.

From sequencer to supercomputer: an automatic pipeline for managing and processing next generation sequencing data.

Identifying common genes and networks in multi-organ fibrosis.

A highly efficient nano-cluster artificial peroxidase and its direct electrochemistry on a nano complex modified glassy carbon electrode.

Impact of alternative reimbursement strategies in the new cooperative medical scheme on caesarean delivery rates: a mixed-method study in rural China.

Pharmacophore and Molecular Docking Guided 3D-QSAR Study of Bacterial Enoyl-ACP Reductase (FabI) Inhibitors.

Design of diffractive phase element for modulating the electric field at the out-of-focus plane in a lens system.

[Determination of podophyllotoxin and total lignans in Sinopodophyllum emodi].

Elevated histone acetylations in Müller cells contribute to inflammation: a novel inhibitory effect of minocycline.

Chromatin modification by SUMO-1 stimulates the promoters of translation machinery genes.

Promoters active in interphase are bookmarked during mitosis by ubiquitination.

Weighted frequent gene co-expression network mining to identify genes involved in genome stability.

JNK3 perpetuates metabolic stress induced by Aβ peptides.

The dose-response decrease in heart rate variability: any association with the metabolites of polycyclic aromatic hydrocarbons in coke oven workers?

New insight into onset of lactation: mediating the negative effect of multiple perinatal biopsychosocial stress on breastfeeding duration.

Canonical and atypical E2Fs regulate the mammalian endocycle.

Integrative genome-wide chromatin signature analysis using finite mixture models.

[The effect of marrow mesenchymal stem cell transplantation on pulmonary fibrosis in rats].

[Analysis of angiogenesis and lymphangiogenesis signaling pathways based on gene expression patterns of nasopharyngeal carcinoma].

Salvianolic acid B inhibits the amyloid formation of human islet amyloid polypeptide and protects pancreatic beta-cells against cytotoxicity.

Contrast-enhanced ultrasonography of the rabbit VX2 tumor model: Analysis of vascular pathology.

A dynamic time order network for time-series gene expression data analysis.

Redistribution of H3K4me2 on neural tissue specific genes during mouse brain development.

DFI: gene feature discovery in RNA-seq experiments from multiple sources.

[Effects of smoking on the concentrations of urinary 10 metabolites of polycyclic aromatic hydrocarbons in coke oven workers].

[Characteristics of particulate matter pollution in coke oven plant].

[Significance and importance of using micronucleus frequencies in peripheral blood lymphocytes as a biomarker for assessing early health of workers exposed to polycyclic aromatic hydrocarbon].

The migration of neural progenitor cell mediated by SDF-1 is NF-κB/HIF-1α dependent upon hypoxia.

Socioeconomic status and care after stroke: results from the Registry of the Canadian Stroke Network.

Genome-wide analysis uncovers high frequency, strong differential chromosomal interactions and their associated epigenetic patterns in E2-mediated gene regulation.

Bisphenol A accelerates toxic amyloid formation of human islet amyloid polypeptide: a possible link between bisphenol A exposure and type 2 diabetes.

Pre-pregnancy body mass index moderates the effect of maternal depressive symptoms on small-for-gestational-age infants.

Curcumin, a potential therapeutic candidate for retinal diseases.

Identify condition-specific gene co-expression networks.

Gene Co-expression analysis predicts genetic aberration loci associated with colon cancer metastasis.

A mixed-method study of factors associated with differences in caesarean section rates at community level: the case of rural China.

Oncogenic role of kinesin proteins and targeting kinesin therapy.

Free energy of translocating an arginine-rich cell-penetrating peptide across a lipid bilayer suggests pore formation.

A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis.

Expression of mRNA transcripts encoding membrane transporters detected with whole transcriptome sequencing of human brain and liver.

Poly(ADP-ribose) polymerase 1 is a key regulator of estrogen receptor α-dependent gene transcription.

Proanthocyanidins are the major anti-diabetic components of cinnamon water extract.

Identifying survival associated morphological features of triple negative breast cancer using multiple datasets.

Occupational exposure to formaldehyde and genetic damage in the peripheral blood lymphocytes of plywood workers.

Dose-response relationships of polycyclic aromatic hydrocarbons exposure and oxidative damage to DNA and lipid in coke oven workers.

Disulfide bonds in amyloidogenesis diseases related proteins.

Time-specific effect of prenatal stressful life events on gestational weight gain.

Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases.

Successful Treatment of Vasculo-Behcet's Disease Presenting as Recurrent Pseudoaneurysms: the Importance of Medical Treatment.

Gene × smoking interactions on human brain gene expression: finding common mechanisms in adolescents and adults.

Autonomic dysreflexia causes chronic immune suppression after spinal cord injury.

The effect of exposing a critical hydrophobic patch on amyloidogenicity and fibril structure of insulin.

Poly(ADP-ribose) polymerase 1 promotes oxidative-stress-induced liver cell death via suppressing farnesoid X receptor α.

MMAD: microarray microdissection with analysis of differences is a computational tool for deconvoluting cell type-specific contributions from tissue samples.

Detection of extracellular RNAs in cancer and viral infection via tethered cationic lipoplex nanoparticles containing molecular beacons.

Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling.

Effect of Liraglutide on endoplasmic reticulum stress in diabetes.

Maternal depressive symptoms related to Epstein-Barr virus reactivation in late pregnancy.

Engineering of metal-clad optical nanocavity to optimize coupling with integrated waveguides.

Helical organic nanotubes from simple chiral building blocks.

Apelin inhibits the development of diabetic nephropathy by regulating histone acetylation in Akita mouse.

Nardosinone protects H9c2 cardiac cells from angiotensin II-induced hypertrophy.

Identification of poly(ADP-ribose) polymerase-1 as a cell cycle regulator through modulating Sp1 mediated transcription in human hepatoma cells.

[Research on structure and UV curing behaviors of novel cardanol-based unsaturated resins using FTIR spectrum analysis method].

A graphene-pure-sulfur sandwich structure for ultrafast, long-life lithium-sulfur batteries.

Epoxy monomers derived from tung oil fatty acids and its regulable thermosets cured in two synergistic ways.

Creation of vectorial bottle-hollow beam using radially or azimuthally polarized light.

Does prenatal maternal stress impair cognitive development and alter temperament characteristics in toddlers with healthy birth outcomes?

[Clinical observations of changes in serum creatine kinase during telbivudin treatment].

NUSAP1 influences the DNA damage response by controlling BRCA1 protein levels.

Polycyclic aromatic hydrocarbons-associated microRNAs and their interactions with the environment: influences on oxidative DNA damage and lipid peroxidation in coke oven workers.

Mining the tissue-tissue gene co-expression network for tumor microenvironment study and biomarker prediction.

Breast cancer patient stratification using a molecular regularized consensus clustering method.

Women are more susceptible than men to oxidative stress and chromosome damage caused by polycyclic aromatic hydrocarbons exposure.

Maternal anxiety during pregnancy and adverse birth outcomes: a systematic review and meta-analysis of prospective cohort studies.

A module of human peripheral blood mononuclear cell transcriptional network containing primitive and differentiation markers is related to specific cardiovascular health variables.

A mouse line for inducible and reversible silencing of specific neurons.

Controlled-Release System of Small Molecules Triggered by the Photothermal Effect of Polypyrrole.

An injectable silk sericin hydrogel promotes cardiac functional recovery after ischemic myocardial infarction.

Precision Medicine: What Challenges Are We Facing?

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).