Department of Clinical Pharmacology
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Kinetics of macrophages, myofibroblasts and mast cells in carbon tetrachloride-induced rat liver cirrhosis.
Anticancer research Mar-Apr, 2002 | Pubmed ID: 12014664
Fetal bladder outlet obstruction in a stillborn bovine fetus.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science Mar, 2003 | Pubmed ID: 12679573
Effect of the CYP2D6 genotype on the pharmacokinetics of tropisetron in healthy Korean subjects.
European journal of clinical pharmacology Jun, 2003 | Pubmed ID: 12728290
Hepatic cirrhosis occurring in a young woodchuck (Marmota monax) due to vertical transmission of woodchuck hepatitis virus (WHV).
Journal of veterinary science Aug, 2003 | Pubmed ID: 14610377
Pharmacokinetic and pharmacodynamic evaluation of a novel proton pump inhibitor, YH1885, in healthy volunteers.
Journal of clinical pharmacology Jan, 2004 | Pubmed ID: 14681344
Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research Jun, 2004 | Pubmed ID: 15173077
Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states.
Clinical pharmacology and therapeutics Aug, 2004 | Pubmed ID: 15289787
Haplotype structure and allele frequencies of CYP2B6 in a Korean population.
Drug metabolism and disposition: the biological fate of chemicals Dec, 2004 | Pubmed ID: 15383491
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.
Clinical pharmacology and therapeutics Nov, 2004 | Pubmed ID: 15536457
Effect of the UGT2B15 genotype on the pharmacokinetics, pharmacodynamics, and drug interactions of intravenous lorazepam in healthy volunteers.
Clinical pharmacology and therapeutics Jun, 2005 | Pubmed ID: 15961980
Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers.
Clinical pharmacology and therapeutics Oct, 2005 | Pubmed ID: 16198653
Up-regulation of Metabotropic glutamate receptor 3 (mGluR3) in rat fibrosis and cirrhosis model of persistent hypoxic condition.
Molecular and cellular biochemistry Jan, 2007 | Pubmed ID: 16845489
Canine renal failure syndrome in three dogs.
Journal of veterinary science Sep, 2006 | Pubmed ID: 16871028
Effects of bio-active ceramic resources in cutaneous wound healing and the role of TGF-beta signaling.
Molecular and cellular biochemistry Jan, 2007 | Pubmed ID: 16871359
Angiotensin II type 1 receptor 1166A/C polymorphism in association with blood pressure response to exogenous angiotensin II.
European journal of clinical pharmacology Jan, 2007 | Pubmed ID: 17146658
Safety, tolerability and pharmacokinetics of udenafil, a novel PDE-5 inhibitor, in healthy young Korean subjects.
British journal of clinical pharmacology Jun, 2008 | Pubmed ID: 18318773
Bone-protecting effect of Rubus coreanus by dual regulation of osteoblasts and osteoclasts.
Menopause (New York, N.Y.) Jul-Aug, 2008 | Pubmed ID: 18709701
Eosinophilic myositis in a slaughtered Korean native cattle.
Journal of veterinary science Dec, 2008 | Pubmed ID: 19043319
Development of Korean Academy of Medical Sciences Guideline rating the physical impairment; kidney, bladder, urethra, male and female reproductive systems (preliminary report).
Journal of Korean medical science May, 2009 | Pubmed ID: 19503685
CYP3A5*3 genotype associated with intrasubject pharmacokinetic variation toward tacrolimus in bioequivalence study.
Therapeutic drug monitoring Feb, 2010 | Pubmed ID: 20010459
Effect of CYP2B6 genotype on the pharmacokinetics of sibutramine and active metabolites in healthy subjects.
Journal of clinical pharmacology Jan, 2011 | Pubmed ID: 20350955
Comparison of the bioavailability and tolerability of fixed-dose combination glimepiride/metformin 2/500-mg tablets versus separate tablets: A single-dose, randomized-sequence, open-label, two-period crossover study in healthy Korean volunteers.
Clinical therapeutics Jul, 2010 | Pubmed ID: 20678687
Activation of MAP kinases during progression of radiation-induced pneumonitis in rats.
Human & experimental toxicology Aug, 2011 | Pubmed ID: 20819845
Effects of pregnane X receptor (NR1I2) and CYP2B6 genetic polymorphisms on the induction of bupropion hydroxylation by rifampin.
Drug metabolism and disposition: the biological fate of chemicals Jan, 2011 | Pubmed ID: 20876786
Evaluation of possible predictive variables for the outcome of shock wave lithotripsy of renal stones.
Korean journal of urology Oct, 2010 | Pubmed ID: 21031093
Safety and pharmacokinetics of intrathecal administration of pemetrexed in rats.
Cancer chemotherapy and pharmacology Aug, 2011 | Pubmed ID: 21107572
Comparison of percutaneous nephrolithotomy using pneumatic lithotripsy (lithoclast®) alone or in combination with ultrasonic lithotripsy.
Korean journal of urology Nov, 2010 | Pubmed ID: 21165200
Effect of HMGCR variant alleles on low-density lipoprotein cholesterol-lowering response to atorvastatin in healthy Korean subjects.
Journal of clinical pharmacology Mar, 2012 | Pubmed ID: 21427285
Pharmacokinetic comparison of sustained- and immediate-release oral formulations of cilostazol in healthy Korean subjects: a randomized, open-label, 3-part, sequential, 2-period, crossover, single-dose, food-effect, and multiple-dose study.
Clinical therapeutics Dec, 2011 | Pubmed ID: 22129569
Effects of cytochrome P450 (CYP)2C19 polymorphisms on pharmacokinetics of phenobarbital in neonates and infants with seizures.
Archives of disease in childhood Jun, 2012 | Pubmed ID: 22331680
Effect of prostatitis on lower urinary tract symptoms: retrospective analysis of prostate biopsy tissue.
Korean journal of urology Feb, 2012 | Pubmed ID: 22379590
One-year outcomes of mid-urethral sling procedures for stress urinary incontinence according to body mass index.
Korean journal of urology Mar, 2012 | Pubmed ID: 22468212
Influence of ABCC2, SLCO1B1, and ABCG2 polymorphisms on the pharmacokinetics of olmesartan.
Journal of cardiovascular pharmacology Jul, 2012 | Pubmed ID: 22494992
The UGT1A3*2 polymorphism affects atorvastatin lactonization and lipid-lowering effect in healthy volunteers.
Pharmacogenetics and genomics Aug, 2012 | Pubmed ID: 22555810
Modeling of the LDL cholesterol-lowering effect of atorvastatin in Korean dyslipidemic patients and non-patient volunteers.
International journal of clinical pharmacology and therapeutics Sep, 2012 | Pubmed ID: 22981146
Impact of ABCC2, ABCG2 and SLCO1B1 polymorphisms on the pharmacokinetics of pitavastatin in humans.
Drug metabolism and pharmacokinetics , 2013 | Pubmed ID: 23007012
Efficacy and safety of emergency ureteroscopic management of ureteral calculi.
Korean journal of urology Sep, 2012 | Pubmed ID: 23061001
Serum cystatin C is a major predictor of vancomycin clearance in a population pharmacokinetic analysis of patients with normal serum creatinine concentrations.
Journal of Korean medical science Jan, 2013 | Pubmed ID: 23341711
Functional characterization of MATE2-K genetic variants and their effects on metformin pharmacokinetics.
Pharmacogenetics and genomics Jul, 2013 | Pubmed ID: 23652408
Sustained Increase in the Oral Bioavailability of Loperamide after a Single Oral Dose of HM30181, a P-glycoprotein Inhibitor, in Healthy Male Participants.
Basic & clinical pharmacology & toxicology Dec, 2013 | Pubmed ID: 23829508
Pharmacokinetics, safety and tolerability of DA-6034, an anti-inflammatory agent, after single and multiple oral administrations in healthy volunteers.
Clinical drug investigation Jan, 2014 | Pubmed ID: 24158940
SIU/ICUD Consultation On Urethral Strictures: Epidemiology, etiology, anatomy, and nomenclature of urethral stenoses, strictures, and pelvic fracture urethral disruption injuries.
Urology Mar, 2014 | Pubmed ID: 24210733
Area under the concentration-time curve to minimum inhibitory concentration ratio as a predictor of vancomycin treatment outcome in methicillin-resistant Staphylococcus aureus bacteraemia.
International journal of antimicrobial agents Feb, 2014 | Pubmed ID: 24315788
Percutaneous nephrolithotomy: comparison of the efficacies and feasibilities of regional and general anesthesia.
Korean journal of urology Dec, 2013 | Pubmed ID: 24363866
Intraocular pharmacokinetics of ranibizumab in vitrectomized versus nonvitrectomized eyes.
Investigative ophthalmology & visual science Jan, 2014 | Pubmed ID: 24398088
The effects of moxifloxacin on QTc interval in healthy Korean male subjects.
Drugs in R&D Jun, 2014 | Pubmed ID: 24691742
Effects of proton pump inhibitors on metformin pharmacokinetics and pharmacodynamics.
Drug metabolism and disposition: the biological fate of chemicals Jul, 2014 | Pubmed ID: 24764147
Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment.
Pharmacogenetics and genomics Oct, 2014 | Pubmed ID: 25029633
Verapamil decreases the glucose-lowering effect of metformin in healthy volunteers.
British journal of clinical pharmacology Dec, 2014 | Pubmed ID: 25060604
Pharmacokinetics and tolerability of the new second-generation nonnucleoside reverse- transcriptase inhibitor KM-023 in healthy subjects.
Drug design, development and therapy , 2014 | Pubmed ID: 25302016
Antihyperglycemic mechanism of metformin occurs via the AMPK/LXRα/POMC pathway.
Scientific reports , 2015 | Pubmed ID: 25634597
Erratum. Intraocular Pharmacokinetics of Ranibizumab in Vitrectomized Versus Nonvitrectomized Eyes.
Investigative ophthalmology & visual science Mar, 2015 | Pubmed ID: 25737148
Pharmacokinetic-pharmacodynamic analysis to evaluate the effect of moxifloxacin on QT interval prolongation in healthy Korean male subjects.
Drug design, development and therapy , 2015 | Pubmed ID: 25750520
Pharmacokinetics of Second-Line Antituberculosis Drugs after Multiple Administrations in Healthy Volunteers.
Antimicrobial agents and chemotherapy Aug, 2015 | Pubmed ID: 25987620
Impact of area under the concentration-time curve to minimum inhibitory concentration ratio on vancomycin treatment outcomes in methicillin-resistant Staphylococcus aureus bacteraemia.
International journal of antimicrobial agents Dec, 2015 | Pubmed ID: 26555059
Discovery of URAT1 SNPs and association between serum uric acid levels and URAT1.
BMJ open , 2015 | Pubmed ID: 26603249
Pharmacokinetics, Safety, and Tolerability of Metformin in Healthy Elderly Subjects.
Journal of clinical pharmacology Dec, 2015 | Pubmed ID: 26710683
The MATE1 rs2289669 polymorphism affects the renal clearance of metformin following ranitidine treatment.
International journal of clinical pharmacology and therapeutics Apr, 2016 | Pubmed ID: 26784938
A thorough QT study to evaluate the QTc prolongation potential of two neuropsychiatric drugs, quetiapine and escitalopram, in healthy volunteers.
International clinical psychopharmacology Jul, 2016 | Pubmed ID: 26950553
Intraocular Pharmacokinetics of Intravitreal Aflibercept (Eylea) in a Rabbit Model.
Investigative ophthalmology & visual science May, 2016 | Pubmed ID: 27258433
An analysis of QTc prolongation with atypical antipsychotic medications and selective serotonin reuptake inhibitors using a large ECG record database.
Expert opinion on drug safety Jun, 2016 | Pubmed ID: 27276059
Seong Joon Ahn1,2,3,
Hye Kyoung Hong1,
Young Mi Na1,
Sang Jun Park1,2,
Jeeyun Ahn1,2,4,
Jaeseong Oh5,
Jae Yong Chung6,
Kyu Hyung Park1,2,
Se Joon Woo1,2
1Department of Ophthalmology, Seoul National University Bundang Hospital,
2Department of Ophthalmology, College of Medicine, Seoul National University,
3Department of Ophthalmology, Hanyang University Hospital,
4Department of Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center,
5Department of Clinical Pharmacology, Seoul National University Hospital,
6Department of Clinical Pharmacology, Seoul National University Bundang Hospital
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