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Department of Anesthesiology
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Molecular basis for species-specific sensitivity to "hot" chili peppers.
Cell Feb, 2002 | Pubmed ID: 11853675
Lessons from peppers and peppermint: the molecular logic of thermosensation.
Current opinion in neurobiology Aug, 2003 | Pubmed ID: 12965298
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1.
Nature Jan, 2004 | Pubmed ID: 14712238
Pungent products from garlic activate the sensory ion channel TRPA1.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2005 | Pubmed ID: 16103371
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
Cell Mar, 2006 | Pubmed ID: 16564016
The menthol receptor TRPM8 is the principal detector of environmental cold.
Nature Jul, 2007 | Pubmed ID: 17538622
Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2007 | Pubmed ID: 17581879
Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder.
European urology Feb, 2008 | Pubmed ID: 18031925
TRPA1 is a major oxidant sensor in murine airway sensory neurons.
The Journal of clinical investigation May, 2008 | Pubmed ID: 18398506
TRPA1 mediates the noxious effects of natural sesquiterpene deterrents.
The Journal of biological chemistry Aug, 2008 | Pubmed ID: 18550530
Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Apr, 2009 | Pubmed ID: 19036859
Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control.
Physiology (Bethesda, Md.) Dec, 2008 | Pubmed ID: 19074743
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2009 | Pubmed ID: 19458046
Sensory detection and responses to toxic gases: mechanisms, health effects, and countermeasures.
Proceedings of the American Thoracic Society Jul, 2010 | Pubmed ID: 20601631
Trigeminal TRPs and the scent of pain.
Pain Jan, 2011 | Pubmed ID: 21122996
Prolonged oxaliplatin exposure alters intracellular calcium signaling: a new mechanism to explain oxaliplatin-associated peripheral neuropathy.
Clinical colorectal cancer Jun, 2011 | Pubmed ID: 21859566
Menthol attenuates respiratory irritation responses to multiple cigarette smoke irritants.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2011 | Pubmed ID: 21903934
TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain.
Pain Oct, 2013 | Pubmed ID: 23820004
A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain.
Current biology : CB Mar, 2014 | Pubmed ID: 24530065
TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury.
American journal of physiology. Lung cellular and molecular physiology Jul, 2014 | Pubmed ID: 24838754
Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice.
PloS one , 2015 | Pubmed ID: 25679525
Effect of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice.
Environmental health perspectives Oct, 2015 | Pubmed ID: 26452297
Duke University Medical Center
Melanie Maya Kaelberer1,2,
Sven-Eric Jordt2
1Department of Cellular & Molecular Physiology, Yale University,
2Department of Anesthesiology, Duke University Medical Center
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