Akira Takashima

Classification of chemotherapeutic agents based on their differential in vitro effects on dendritic cells.

Induction of tumor-specific protective immunity by in situ Langerhans cell vaccine.

Killing of naive T cells by CD95L-transfected dendritic cells (DC): in vivo study using killer DC-DC hybrids and CD4(+) T cells from DO11.10 mice.

CD39 is the dominant Langerhans cell-associated ecto-NTPDase: modulatory roles in inflammation and immune responsiveness.

Dendritic cell-based immunoregulatory strategies.

Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during antigen presentation.

Synthesis and surface expression of hyaluronan by dendritic cells and its potential role in antigen presentation.

Reduction of antiviral CD8 lymphocytes in vivo with dendritic cells expressing Fas ligand-increased survival of viral (lymphocytic choriomeningitis virus) central nervous system infection.

Functional roles of hyaluronan in B16-F10 melanoma growth and experimental metastasis in mice.

Hair follicles serve as local reservoirs of skin mast cell precursors.

Drug-inducible, dendritic cell-based genetic immunization.

Stimulus-dependent deacylation of bacterial lipopolysaccharide by dendritic cells.

Generation and function of reactive oxygen species in dendritic cells during antigen presentation.

Involvement of hyaluronan in epidermal Langerhans cell maturation and migration in vivo.

Keratinocyte ATP release assay for testing skin-irritating potentials of structurally diverse chemicals.

CD1a and langerin: acting as more than Langerhans cell markers.

Langerhans cells in CD44-deficient mice emigrate from the epidermis but fail to reach the lymph nodes after hapten application.

Cloning and characterization of Trichophyton rubrum genes encoding actin, Tri r2, and Tri r4.

New strategy for efficient selection of dendritic cell-tumor hybrids and clonal heterogeneity of resulting hybrids.

A library-selected, Langerhans cell-targeting peptide enhances an immune response.

Volume, trend and citation analyses of skin related publications from 1966 to 2003.

Differential activation profiles of multiple transcription factors during dendritic cell maturation.

Discovery of novel immunostimulants by dendritic-cell-based functional screening.

dsRNA-mediated innate immunity of epidermal keratinocytes.

Lipopolysaccharide deacylation by an endogenous lipase controls innate antibody responses to Gram-negative bacteria.

Identification of novel pharmacological activities of an antifungal agent, nystatin, to promote dendritic cell maturation.

Behavioral responses of epidermal Langerhans cells in situ to local pathological stimuli.

GM-CSF-surface-modified B16.F10 melanoma cell vaccine.

Development of intravital intermittent confocal imaging system for studying Langerhans cell turnover.

Functional significance of passive and active dendritic properties in the synaptic integration by an identified nonspiking interneuron of crayfish.

Roles for IL-1 and TNFalpha in dynamic behavioral responses of Langerhans cells to topical hapten application.

Four-dimensional multiphoton confocal microscopy: the new frontier in cellular imaging.

Local thermal injury elicits immediate dynamic behavioural responses by corneal Langerhans cells.

Colchicine promotes antigen cross-presentation by murine dendritic cells.

Epidermal langerhans cell movement in situ: a model for understanding immunologic function in the skin.

Dermal immunopathology: from genetics to effector mechanisms.

Effects of active conductance distribution over dendrites on the synaptic integration in an identified nonspiking interneuron.

Identification of crassin acetate as a new immunosuppressant triggering heme oxygenase-1 expression in dendritic cells.

Dual therapeutic efficacy of vinblastine as a unique chemotherapeutic agent capable of inducing dendritic cell maturation.

IL-33 promotes DC development in BM culture by triggering GM-CSF production.

Reconstruction of virtual neural circuits in an insect brain.

Thymic stromal lymphopoietin induces tight junction protein claudin-7 via NF-kappaB in dendritic cells.

Intravital imaging of IL-1beta production in skin.

Bidirectional homing of Tregs between the skin and lymph nodes.

Cyclophosphamide, DCs, and Tregs.

Real-time visualization of macromolecule uptake by epidermal Langerhans cells in living animals.

[Series: Diagnosis at a glance].

Development and validation of a new in vitro assay designed to measure contact allergen-triggered oxidative stress in dendritic cells.

Constrictive pericarditis with intrapericardial abscess.

Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice.

Neutrophil differentiation into a unique hybrid population exhibiting dual phenotype and functionality of neutrophils and dendritic cells.

Emergence, origin, and function of neutrophil-dendritic cell hybrids in experimentally induced inflammatory lesions in mice.

Harnessing DCs by substance P.

Reciprocal regulation of development of neutrophil-dendritic cell hybrids in mice by IL-4 and interferon-gamma.

Cryotherapy with concurrent CpG oligonucleotide treatment controls local tumor recurrence and modulates HER2/neu immunity.

Cardiac rehabilitation reduces serum levels of oxidized low-density lipoprotein.

Effects of docosahexaenoic Acid on the endothelial function in patients with coronary artery disease.

Serum concentration of eicosapentaenoic acid is associated with cognitive function in patients with coronary artery disease.

Histopathological heterogeneity of in-stent restenosis in four coronary endarterectomy specimens.

Neutrophil priming occurs in a sequential manner and can be visualized in living animals by monitoring IL-1β promoter activation.

Effect of combination tablets containing amlodipine 10 mg and irbesartan 100 mg on blood pressure and cardiovascular risk factors in patients with hypertension.

Neutrophil plasticity: acquisition of phenotype and functionality of antigen-presenting cell.

IL-1α Gene Deletion Protects Oligodendrocytes after Spinal Cord Injury through Upregulation of the Survival Factor Tox3.

Reduced ratio of eicosapentaenoic acid and docosahexaenoic acid to arachidonic acid is associated with early onset of acute coronary syndrome.

Erratum to: 'Reduced ratio of eicosapentaenoic acid and docosahexaenoic acid to arachidonic acid is associated with early onset of acute coronary syndrome'.

Vegetation in the coronary sinus that concealed the presence of a coronary arteriovenous fistula in a patient with infectious endocarditis.