Nathan J. Alves
Center for Bio/Molecular Science & Engineering
Naval Research Laboratory
Dr. Alves received his PhD in Chemical and Biomolecular Engineering from the University of Notre Dame. The research he conducts, while spanning many disciplines, is centered on the development of translational technologies, treatments, and techniques that can be utilized to have a positive impact on people’s lives.
He has extensive experience in: site-specific antibody modification, oriented antibody immobilization for advanced diagnostics, nanoparticle delivery, and packaging of pharmaceutical agents/enzymes to treat various diseases. Currently, Dr. Alves is an Assistant Professor at the Indiana University School of Medicine in the Department of Emergency Medicine with a joint appointment at Purdue in Biomedical Engineering. His multidisciplinary background affords him a unique perspective to tackle complex medical device and therapeutic development problems.
Comparative study on the inhibition of plasmin and delta-plasmin via benzamidine derivatives.
Biochemical and biophysical research communications Feb, 2015 | Pubmed ID: 25576865
Comparison of isoflurane and α-chloralose in an anesthetized swine model of acute pulmonary embolism producing right ventricular dysfunction.
Comparative medicine Feb, 2015 | Pubmed ID: 25730758
Variable Resistance to Plasminogen Activator Initiated Fibrinolysis for Intermediate-Risk Pulmonary Embolism.
PloS one , 2016 | Pubmed ID: 26866684
Affinity purification of bacterial outer membrane vesicles (OMVs) utilizing a His-tag mutant.
Research in microbiology Oct, 2016 | Pubmed ID: 27773766
Disinhibiting neurons in the dorsomedial hypothalamus delays the onset of exertional fatigue and exhaustion in rats exercising in a warm environment.
Brain research 06, 2018 | Pubmed ID: 29577887
Environmental Decontamination of a Chemical Warfare Simulant Utilizing a Membrane Vesicle-Encapsulated Phosphotriesterase.
ACS applied materials & interfaces May, 2018 | Pubmed ID: 29672020
HIV-Nef Protein Persists in the Lungs of Aviremic Patients with HIV and Induces Endothelial Cell Death.
American journal of respiratory cell and molecular biology 03, 2019 | Pubmed ID: 30321057
Inhaled nitric oxide to control platelet hyper-reactivity in patients with acute submassive pulmonary embolism.
Nitric oxide : biology and chemistry 03, 2020 | Pubmed ID: 31940502
Fibrin clot formation under diverse clotting conditions: Comparing turbidimetry and thromboelastography.
Thrombosis research Mar, 2020 | Pubmed ID: 31954276
Real-time tracking of fibrinolysis under constant wall shear and various pulsatile flows in an in-vitro thrombolysis model.
Bioengineering & translational medicine May, 2023 | Pubmed ID: 37206217
Equivalence Study of Semaxanib from Different Suppliers.
American journal of respiratory cell and molecular biology Dec, 2020 | Pubmed ID: 33258679
Antibody conjugation and formulation.
Antibody therapeutics Jan, 2019 | Pubmed ID: 33928219
In-vitro thromboelastographic characterization of reconstituted whole blood utilizing cryopreserved platelets.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis Dec, 2021 | Pubmed ID: 34475333
Environmental microplastic and nanoplastic: Exposure routes and effects on coagulation and the cardiovascular system.
Environmental pollution (Barking, Essex : 1987) Dec, 2021 | Pubmed ID: 34563850
Fluorescently conjugated annular fibrin clot for multiplexed real-time digestion analysis.
Journal of materials chemistry. B Nov, 2021 | Pubmed ID: 34698753
Modulation of soluble guanylate cyclase ameliorates pulmonary hypertension in a rat model of chronic thromboembolic pulmonary hypertension by stimulating angiogenesis.
Physiological reports Jan, 2022 | Pubmed ID: 35001565
Use of the "Future Life Map" exercise to improve awareness of career options and opportunities in underrepresented minority undergraduate students pursuing STEM careers.
PloS one , 2022 | Pubmed ID: 35143578
Stabilization protects islet integrity during respirometry in the Oroboros Oxygraph-2K analyzer.
Islets Dec, 2022 | Pubmed ID: 35331085
Multivalent Benzamidine Molecules for Plasmin Inhibition: Effect of Valency and Linker Length.
ChemMedChem Nov, 2022 | Pubmed ID: 36111842
Microplastic Effects on Thrombin-Fibrinogen Clotting Dynamics Measured via Turbidity and Thromboelastography.
Biomolecules Dec, 2022 | Pubmed ID: 36551292
Effect of Chandler loop shear and tubing size on thrombus architecture.
Journal of materials science. Materials in medicine May, 2023 | Pubmed ID: 37173603
Exploring microplastic impact on whole blood clotting dynamics utilizing thromboelastography.
Frontiers in public health , 2023 | Pubmed ID: 37521965
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