Cell,
Developmental & Cancer Biology,
Knight Cancer Institute,
Cell, Developmental & Cancer Biology
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Matrix metalloproteinase inhibitors and cancer: trials and tribulations.
Science (New York, N.Y.) Mar, 2002 | Pubmed ID: 11923519
RECKing MMP function: implications for cancer development.
Trends in cell biology May, 2002 | Pubmed ID: 12062160
MMP9 potentiates pulmonary metastasis formation.
Cancer cell Oct, 2002 | Pubmed ID: 12398887
Inflammation and cancer.
Nature Dec 19-26, 2002 | Pubmed ID: 12490959
Epithelial carcinogenesis: dynamic interplay between neoplastic cells and their microenvironment.
Differentiation; research in biological diversity Dec, 2002 | Pubmed ID: 12492502
Immune enhancement of skin carcinogenesis by CD4+ T cells.
The Journal of experimental medicine Apr, 2003 | Pubmed ID: 12695493
The tumor microenvironment: a critical determinant of neoplastic evolution.
European journal of cell biology Nov, 2003 | Pubmed ID: 14703010
TIMP-1 alters susceptibility to carcinogenesis.
Cancer research Feb, 2004 | Pubmed ID: 14871825
Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment.
Cancer research Mar, 2004 | Pubmed ID: 14996727
Matrix metalloproteinase-2 and -9 expression increases in Mycoplasma-infected airways but is not required for microvascular remodeling.
American journal of physiology. Lung cellular and molecular physiology Aug, 2004 | Pubmed ID: 15075248
Cancer: an inflammatory link.
Nature Sep, 2004 | Pubmed ID: 15385993
Early neoplastic progression is complement independent.
Neoplasia (New York, N.Y.) Nov-Dec, 2004 | Pubmed ID: 15720803
Soluble mediators of inflammation during tumor development.
Advances in cancer research , 2005 | Pubmed ID: 15797447
The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent.
Cancer research Apr, 2005 | Pubmed ID: 15833851
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent.
Cancer cell May, 2005 | Pubmed ID: 15894262
Paradoxical roles of the immune system during cancer development.
Nature reviews. Cancer Jan, 2006 | Pubmed ID: 16397525
Inflammation, proteases and cancer.
European journal of cancer (Oxford, England : 1990) Apr, 2006 | Pubmed ID: 16524717
The inflammatory tumor microenvironment and its impact on cancer development.
Contributions to microbiology , 2006 | Pubmed ID: 16627962
A selective activity-based probe for the papain family cysteine protease dipeptidyl peptidase I/cathepsin C.
Journal of the American Chemical Society May, 2006 | Pubmed ID: 16637611
Analysis of immune cell infiltrates during squamous carcinoma development.
The journal of investigative dermatology. Symposium proceedings Sep, 2006 | Pubmed ID: 17069009
Tumor progression and metastasis from genetic to microenvironmental determinants: a workshop of the tumor progression and metastasis NIH study section in honor of Dr. Martin L. Padarathsingh, May 31, 2006, Georgetown, Washington, DC.
Cancer biology & therapy Dec, 2006 | Pubmed ID: 17224636
Immune cells as anti-cancer therapeutic targets and tools.
Journal of cellular biochemistry Jul, 2007 | Pubmed ID: 17265430
Humoral immunity, inflammation and cancer.
Current opinion in immunology Apr, 2007 | Pubmed ID: 17276050
IKKalpha at the crossroads of inflammation and metastasis.
Cell Apr, 2007 | Pubmed ID: 17418780
Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development.
Developmental dynamics : an official publication of the American Association of Anatomists Jun, 2007 | Pubmed ID: 17440987
Hu/Mu ProtIn oligonucleotide microarray: dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironment.
Molecular cancer research : MCR May, 2007 | Pubmed ID: 17510311
Distinctive features of angiogenesis and lymphangiogenesis determine their functionality during de novo tumor development.
Cancer research Jun, 2007 | Pubmed ID: 17545601
Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression.
Breast cancer research : BCR , 2007 | Pubmed ID: 17705880
Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling.
Cancer research Sep, 2007 | Pubmed ID: 17875701
Tumor stroma and regulation of cancer development.
Annual review of pathology , 2006 | Pubmed ID: 18039110
Immune cells as mediators of solid tumor metastasis.
Cancer metastasis reviews Mar, 2008 | Pubmed ID: 18066650
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
The Journal of clinical investigation Apr, 2008 | Pubmed ID: 18340378
Polarized immune responses differentially regulate cancer development.
Immunological reviews Apr, 2008 | Pubmed ID: 18363999
Genetic and cellular mechanisms of oncogenesis.
Current opinion in genetics & development Feb, 2008 | Pubmed ID: 18440220
Inflaming gastrointestinal oncogenic programming.
Cancer cell Jul, 2008 | Pubmed ID: 18598939
Three-dimensional visualization of blood and lymphatic vasculature in tissue whole mounts using confocal microscopy.
Current protocols in cytometry May, 2005 | Pubmed ID: 18770816
Development of an optimized activatable MMP-14 targeted SPECT imaging probe.
Bioorganic & medicinal chemistry Jan, 2009 | Pubmed ID: 19109023
Delineating protease functions during cancer development.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19377975
CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages.
Cancer cell Aug, 2009 | Pubmed ID: 19647220
Collagen-based cell migration models in vitro and in vivo.
Seminars in cell & developmental biology Oct, 2009 | Pubmed ID: 19682592
Optical imaging of the peri-tumoral inflammatory response in breast cancer.
Journal of translational medicine , 2009 | Pubmed ID: 19906309
Lymphocytes in cancer development: polarization towards pro-tumor immunity.
Cytokine & growth factor reviews Feb, 2010 | Pubmed ID: 20005150
FcRgamma activation regulates inflammation-associated squamous carcinogenesis.
Cancer cell Feb, 2010 | Pubmed ID: 20138013
Stromal regulation of vessel stability by MMP14 and TGFbeta.
Disease models & mechanisms May-Jun, 2010 | Pubmed ID: 20223936
Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor.
International journal of cancer Jan, 2011 | Pubmed ID: 20232379
Cancer and inflammation: promise for biologic therapy.
Journal of immunotherapy (Hagerstown, Md. : 1997) May, 2010 | Pubmed ID: 20386472
Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity.
Cancer metastasis reviews Jun, 2010 | Pubmed ID: 20405169
Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression.
Cancer research Oct, 2010 | Pubmed ID: 20841473
Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response.
Cancer research Oct, 2010 | Pubmed ID: 20924104
Leukocytes in mammary development and cancer.
Cold Spring Harbor perspectives in biology Mar, 2011 | Pubmed ID: 21123394
The tumor-immune microenvironment and response to radiation therapy.
Journal of mammary gland biology and neoplasia Dec, 2010 | Pubmed ID: 21161342
Histamine restricts cancer: nothing to sneeze at.
Nature medicine Jan, 2011 | Pubmed ID: 21217680
Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization.
International journal of cancer. Journal international du cancer Jun, 2011 | Pubmed ID: 21387299
Protective role of cathepsin L in mouse skin carcinogenesis.
Molecular carcinogenesis Apr, 2012 | Pubmed ID: 21538579
B regulatory cells and the tumor-promoting actions of TNF-α during squamous carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2011 | Pubmed ID: 21670304
MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles.
Clinical cancer research : an official journal of the American Association for Cancer Research Sep, 2011 | Pubmed ID: 21791632
Leukocyte composition of human breast cancer.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 21825174
Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy.
Cancer discovery Jun, 2011 | Pubmed ID: 22039576
Immune microenvironments in solid tumors: new targets for therapy.
Genes & development Dec, 2011 | Pubmed ID: 22190457
Differential macrophage programming in the tumor microenvironment.
Trends in immunology Mar, 2012 | Pubmed ID: 22277903
Respiratory Homeostasis and Exploitation of the Immune System for Lung Cancer Vaccines.
US oncology , 2009 | Pubmed ID: 22368692
Tumor microenvironment complexity: emerging roles in cancer therapy.
Cancer research May, 2012 | Pubmed ID: 22414581
Accessories to the crime: functions of cells recruited to the tumor microenvironment.
Cancer cell Mar, 2012 | Pubmed ID: 22439926
MR imaging of tumor-associated macrophages.
Oncoimmunology Jul, 2012 | Pubmed ID: 22754769
Neutralizing tumor-promoting chronic inflammation: a magic bullet?
Science (New York, N.Y.) Jan, 2013 | Pubmed ID: 23329041
B cells and their mediators as targets for therapy in solid tumors.
Experimental cell research Jul, 2013 | Pubmed ID: 23499742
Some DCs are "B"etter.
Immunity Apr, 2013 | Pubmed ID: 23601679
Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2013 | Pubmed ID: 23851682
Cathepsin C is a tissue-specific regulator of squamous carcinogenesis.
Genes & development Oct, 2013 | Pubmed ID: 24065739
Dendritic cells, inflammation, and breast cancer.
Cancer journal (Sudbury, Mass.) Nov-Dec, 2013 | Pubmed ID: 24270350
Poker face no more: cancer recurrence reveals its hand.
Nature medicine Dec, 2013 | Pubmed ID: 24309652
CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8(+) T cells.
Oncoimmunology Dec, 2013 | Pubmed ID: 24498562
A Listeria vaccine and depletion of T-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice.
Gastroenterology Jun, 2014 | Pubmed ID: 24607504
B cells regulate macrophage phenotype and response to chemotherapy in squamous carcinomas.
Cancer cell Jun, 2014 | Pubmed ID: 24909985
Mammary gland involution as an immunotherapeutic target for postpartum breast cancer.
Journal of mammary gland biology and neoplasia Jul, 2014 | Pubmed ID: 24952477
Manipulating microRNAs to regulate macrophage polarization in gliomas.
Journal of the National Cancer Institute Aug, 2014 | Pubmed ID: 25136034
Duality of the immune response in cancer: lessons learned from skin.
The Journal of investigative dermatology Oct, 2014 | Pubmed ID: 25302470
Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells.
Cancer cell Nov, 2014 | Pubmed ID: 25446896
TH2-Polarized CD4(+) T Cells and Macrophages Limit Efficacy of Radiotherapy.
Cancer immunology research May, 2015 | Pubmed ID: 25716473
Macrophages and therapeutic resistance in cancer.
Cancer cell Apr, 2015 | Pubmed ID: 25858805
Myeloid Cells as Targets for Therapy in Solid Tumors.
Cancer journal (Sudbury, Mass.) Jul-Aug, 2015 | Pubmed ID: 26222088
Senescence and cancer: An evolving inflammatory paradox.
Biochimica et biophysica acta Jan, 2016 | Pubmed ID: 26453912
Immune response to cancer therapy: mounting an effective antitumor response and mechanisms of resistance.
Trends in cancer Sep, 2015 | Pubmed ID: 26457331
Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer.
Cancer discovery Jan, 2016 | Pubmed ID: 26552413
Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer.
Cancer discovery Mar, 2016 | Pubmed ID: 26715645
The Basis of Oncoimmunology.
Cell Mar, 2016 | Pubmed ID: 26967289
Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma.
Oncoimmunology Mar, 2016 | Pubmed ID: 27141370
Alk5 inhibition increases delivery of macromolecular and protein-bound contrast agents to tumors.
JCI insight May, 2016 | Pubmed ID: 27182558
AACR Cancer Progress Report 2016.
Clinical cancer research : an official journal of the American Association for Cancer Research Oct, 2016 | Pubmed ID: 27697776
Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis.
The Journal of investigative dermatology Feb, 2017 | Pubmed ID: 27720760
MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment.
Nature communications Nov, 2016 | Pubmed ID: 27886180
Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions.
Cellular and molecular gastroenterology and hepatology Mar, 2017 | Pubmed ID: 28275683
Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis.
Cell reports Apr, 2017 | Pubmed ID: 28380359
Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition.
Cancer discovery Jun, 2017 | Pubmed ID: 28652380
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