The Shapiro Family Laboratory of Viral Oncology and Aging Research
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The telomeric length and heterogeneity decrease with age in normal human oral keratinocytes.
Mechanisms of ageing and development Mar, 2002 | Pubmed ID: 11850022
Senescence-associated decline in the intranuclear accumulation of hOGG1-alpha and impaired 8-oxo-dG repair activity in senescing normal human oral keratinocytes in vivo.
Experimental cell research Oct, 2005 | Pubmed ID: 16122734
Abnormal DNA end-joining activity in human head and neck cancer.
International journal of molecular medicine May, 2006 | Pubmed ID: 16596281
Heterogeneous nuclear ribonucleoprotein G shows tumor suppressive effect against oral squamous cell carcinoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2006 | Pubmed ID: 16707624
Bmi-1 cooperates with human papillomavirus type 16 E6 to immortalize normal human oral keratinocytes.
Experimental cell research Feb, 2007 | Pubmed ID: 17161394
p53 promotes the fidelity of DNA end-joining activity by, in part, enhancing the expression of heterogeneous nuclear ribonucleoprotein G.
DNA repair Jun, 2007 | Pubmed ID: 17387044
hnRNP G elicits tumor-suppressive activity in part by upregulating the expression of Txnip.
Biochemical and biophysical research communications Aug, 2008 | Pubmed ID: 18541147
HIV-1 Tat enhances replicative potential of human oral keratinocytes harboring HPV-16 genome.
International journal of oncology Oct, 2008 | Pubmed ID: 18813791
Association of hsp90 to the hTERT promoter is necessary for hTERT expression in human oral cancer cells.
Carcinogenesis Dec, 2008 | Pubmed ID: 18820283
Bmi-1 extends the life span of normal human oral keratinocytes by inhibiting the TGF-beta signaling.
Experimental cell research Oct, 2010 | Pubmed ID: 20630502
Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes.
The Journal of biological chemistry Dec, 2010 | Pubmed ID: 20938050
miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras.
Biochemical and biophysical research communications Jan, 2011 | Pubmed ID: 21167132
Radioprotective effects of Bmi-1 involve epigenetic silencing of oxidase genes and enhanced DNA repair in normal human keratinocytes.
The Journal of investigative dermatology Jun, 2011 | Pubmed ID: 21307872
Impaired odontogenic differentiation of senescent dental mesenchymal stem cells is associated with loss of Bmi-1 expression.
Journal of endodontics May, 2011 | Pubmed ID: 21496667
Identification of senescence-inducing microRNAs in normal human keratinocytes.
International journal of oncology Nov, 2011 | Pubmed ID: 21725593
Expression and mutation analysis of heterogeneous nuclear ribonucleoprotein G in human oral cancer.
Oral oncology Nov, 2011 | Pubmed ID: 21840245
DeltaNp63α protein triggers epithelial-mesenchymal transition and confers stem cell properties in normal human keratinocytes.
The Journal of biological chemistry Nov, 2011 | Pubmed ID: 21880709
TNFα enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells.
Biochemical and biophysical research communications Jul, 2012 | Pubmed ID: 22728043
Therapeutic potential of mesenchymal stem cells for oral and systemic diseases.
Dental clinics of North America Jul, 2012 | Pubmed ID: 22835544
Camphorquinone inhibits odontogenic differentiation of dental pulp cells and triggers release of inflammatory cytokines.
Journal of endodontics Jan, 2013 | Pubmed ID: 23228258
Efavirenz induces autophagy and aberrant differentiation in normal human keratinocytes.
International journal of molecular medicine Jun, 2013 | Pubmed ID: 23563240
2-Hydroxyethyl methacrylate inhibits migration of dental pulp stem cells.
Journal of endodontics Sep, 2013 | Pubmed ID: 23953290
A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway.
Cell Nov, 2013 | Pubmed ID: 24267888
Development of oral osteomucosal tissue constructs in vitro and localization of fluorescently-labeled bisphosphonates to hard and soft tissue.
International journal of molecular medicine Aug, 2014 | Pubmed ID: 24920042
Gene expression signatures affected by ethanol and/or nicotine in normal human normal oral keratinocytes (NHOKs).
Genomics data Dec, 2014 | Pubmed ID: 25126520
Impaired bone resorption and woven bone formation are associated with development of osteonecrosis of the jaw-like lesions by bisphosphonate and anti-receptor activator of NF-κB ligand antibody in mice.
The American journal of pathology Nov, 2014 | Pubmed ID: 25173134
Osteo-/odontogenic differentiation of induced mesenchymal stem cells generated through epithelial-mesenchyme transition of cultured human keratinocytes.
Journal of endodontics Nov, 2014 | Pubmed ID: 25201509
The p63 Gene Is Regulated by Grainyhead-like 2 (GRHL2) through Reciprocal Feedback and Determines the Epithelial Phenotype in Human Keratinocytes.
The Journal of biological chemistry Aug, 2015 | Pubmed ID: 26085095
Regulation of p53 during senescence in normal human keratinocytes.
Aging cell Oct, 2015 | Pubmed ID: 26138448
Elevated expression of JMJD6 is associated with oral carcinogenesis and maintains cancer stemness properties.
Carcinogenesis Feb, 2016 | Pubmed ID: 26645717
Human papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation.
Papillomavirus research (Amsterdam, Netherlands) Dec, 2015 | Pubmed ID: 26693182
Managing Intraoral Lesions in Oral Cancer Patients in a General Dental Practice: An Overview.
Journal of the California Dental Association Feb, 2016 | Pubmed ID: 26930751
Grainyhead-like 2 regulates epithelial plasticity and stemness in oral cancer cells.
Carcinogenesis May, 2016 | Pubmed ID: 26933170
Modeling the Etiology of p53-mutated Cancer Cells.
The Journal of biological chemistry May, 2016 | Pubmed ID: 27022024
Orai1 mediates osteogenic differentiation via BMP signaling pathway in bone marrow mesenchymal stem cells.
Biochemical and biophysical research communications May, 2016 | Pubmed ID: 27086849
Orai1 promotes tumor progression by enhancing cancer stemness via NFAT signaling in oral/oropharyngeal squamous cell carcinoma.
Oncotarget Jul, 2016 | Pubmed ID: 27259269
IL-36 Induces Bisphosphonate-Related Osteonecrosis of the Jaw-Like Lesions in Mice by Inhibiting TGF-β-Mediated Collagen Expression.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Aug, 2016 | Pubmed ID: 27567012
Preexisting Periapical Inflammatory Condition Exacerbates Tooth Extraction-induced Bisphosphonate-related Osteonecrosis of the Jaw Lesions in Mice.
Journal of endodontics Nov, 2016 | Pubmed ID: 27637460
Clinical and Molecular Perspectives of Reparative Dentin Formation: Lessons Learned from Pulp-Capping Materials and the Emerging Roles of Calcium.
Dental clinics of North America Jan, 2017 | Pubmed ID: 27912821
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