School of Biosciences
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Probing ligand recognition in the decarboxylase antibody 21D8: implications for the catalytic mechanism.
Biochemistry Jan, 2002 | Pubmed ID: 11790098
Catalysis on the coastline: theozyme, molecular dynamics, and free energy perturbation analysis of antibody 21D8 catalysis of the decarboxylation of 5-nitro-3-carboxybenzisoxazole.
Journal of computational chemistry Jan, 2003 | Pubmed ID: 12483679
Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase.
Journal of the American Chemical Society Mar, 2003 | Pubmed ID: 12643694
Precursor-directed biosynthesis of epothilone in Escherichia coli.
Journal of the American Chemical Society Jun, 2004 | Pubmed ID: 15198579
Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles.
Journal of the American Chemical Society Jul, 2004 | Pubmed ID: 15225061
Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli.
Nature chemical biology Aug, 2006 | Pubmed ID: 16799553
Biosynthesis of the 3,4-dihydroxybenzoate moieties of petrobactin by Bacillus anthracis.
The Journal of organic chemistry Aug, 2008 | Pubmed ID: 18582113
The missing link in petrobactin biosynthesis: asbF encodes a (-)-3-dehydroshikimate dehydratase.
Biochemistry Nov, 2008 | Pubmed ID: 18975921
Complete sequence of biosynthetic gene cluster responsible for producing triostin A and evaluation of quinomycin-type antibiotics from Streptomyces triostinicus.
Biotechnology progress Nov-Dec, 2008 | Pubmed ID: 19194935
Chapter 15. Plasmid-borne gene cluster assemblage and heterologous biosynthesis of nonribosomal peptides in Escherichia coli.
Methods in enzymology , 2009 | Pubmed ID: 19374991
Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent antibiotic unnatural natural product.
Journal of the American Chemical Society Jul, 2009 | Pubmed ID: 19514719
Rationally engineered total biosynthesis of a synthetic analogue of a natural quinomycin depsipeptide in Escherichia coli.
Chembiochem : a European journal of chemical biology Aug, 2009 | Pubmed ID: 19588480
Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation.
Nature immunology Oct, 2009 | Pubmed ID: 19718029
Siderophore-mediated iron acquisition in Bacillus anthracis and related strains.
Microbiology (Reading, England) Jul, 2010 | Pubmed ID: 20466767
Enzymatic epoxide-opening cascades catalyzed by a pair of epoxide hydrolases in the ionophore polyether biosynthesis.
Organic letters Apr, 2011 | Pubmed ID: 21375229
Structural and functional studies of trans-encoded HLA-DQ2.3 (DQA1*03:01/DQB1*02:01) protein molecule.
The Journal of biological chemistry Apr, 2012 | Pubmed ID: 22362761
Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis.
Nature Mar, 2012 | Pubmed ID: 22388816
Establishing a new methodology for genome mining and biosynthesis of polyketides and peptides through yeast molecular genetics.
Chembiochem : a European journal of chemical biology Apr, 2012 | Pubmed ID: 22447505
Overexpressing transcriptional regulator in Aspergillus oryzae activates a silent biosynthetic pathway to produce a novel polyketide.
Chembiochem : a European journal of chemical biology Apr, 2012 | Pubmed ID: 22447538
Overexpressing transcriptional regulator in Chaetomium globosum activates a silent biosynthetic pathway: evaluation of shanorellin biosynthesis.
The Journal of antibiotics Jul, 2012 | Pubmed ID: 22569160
Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis.
Journal of the American Chemical Society May, 2013 | Pubmed ID: 23611317
Yeast-based genome mining, production and mechanistic studies of the biosynthesis of fungal polyketide and peptide natural products.
Natural product reports Aug, 2013 | Pubmed ID: 23824111
Echinomycin biosynthesis.
Current opinion in chemical biology Aug, 2013 | Pubmed ID: 23856054
Targeted disruption of transcriptional regulators in Chaetomium globosum activates biosynthetic pathways and reveals transcriptional regulator-like behavior of aureonitol.
Journal of the American Chemical Society Sep, 2013 | Pubmed ID: 23941144
Engineering the polyproline II propensity of a class II major histocompatibility complex ligand peptide.
ACS chemical biology Nov, 2013 | Pubmed ID: 24001370
Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk.
Nature chemical biology Dec, 2013 | Pubmed ID: 24121553
Conversion of a disulfide bond into a thioacetal group during echinomycin biosynthesis.
Angewandte Chemie (International ed. in English) Jan, 2014 | Pubmed ID: 24302672
Cytochrome P450 as dimerization catalyst in diketopiperazine alkaloid biosynthesis.
Chembiochem : a European journal of chemical biology Mar, 2014 | Pubmed ID: 24677498
Biophysical properties of intrinsically disordered p130Cas substrate domain--implication in mechanosensing.
PLoS computational biology Apr, 2014 | Pubmed ID: 24722239
Elucidation of pseurotin biosynthetic pathway points to trans-acting C-methyltransferase: generation of chemical diversity.
Angewandte Chemie (International ed. in English) Aug, 2014 | Pubmed ID: 24939566
Non-heme dioxygenase catalyzes atypical oxidations of 6,7-bicyclic systems to form the 6,6-quinolone core of viridicatin-type fungal alkaloids.
Angewandte Chemie (International ed. in English) Nov, 2014 | Pubmed ID: 25251934
Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis.
Journal of the American Chemical Society Jan, 2015 | Pubmed ID: 25535803
Involvement of Lipocalin-like CghA in Decalin-Forming Stereoselective Intramolecular [4+2] Cycloaddition.
Chembiochem : a European journal of chemical biology Nov, 2015 | Pubmed ID: 26360642
Elucidation of Pyranonigrin Biosynthetic Pathway Reveals a Mode of Tetramic Acid, Fused γ-Pyrone, and exo-Methylene Formation.
Organic letters Oct, 2015 | Pubmed ID: 26414728
Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis.
Angewandte Chemie (International ed. in English) May, 2016 | Pubmed ID: 27072782
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