Melissa D. Krebs
Department of Chemical & Biological Engineering,
Department of Chemical and Biological Engineering
Colorado School of Mines
Melissa received a B.S. and M.S. in Chemical Engineering from the University of Rochester. She then worked at Charles Stark Draper Laboratory, Inc. in Cambridge, MA, focusing on applications in biodefense and medical diagnostics. She returned to graduate school to pursue a Ph.D. in Biomedical Engineering at Case Western Reserve University in Cleveland, OH in the field of biomaterials and tissue regeneration and was awarded a National Science Foundation Graduate Fellowship to support her work. After graduating with her Ph.D., Melissa was an American Cancer Society Postdoctoral Fellow and Research Assistant Professor in Biomedical Engineering at Case Western Reserve University. She was awarded the TERMIS Wake Forest Institute for Regenerative Medicine Young Investigator Award. She also spent a year as a Visiting Scientist in Cancer Biology at University of Colorado Anschutz Medical Campus. Melissa is now an Associate Professor in Chemical & Biological Engineering at Colorado School of Mines; she joined the department in August 2012. She is also a faculty member in the Charles Gates Center for Regenerative Medicine & Stem Cell Biology and is an Adjoint Associate Professor in Ophthalmology at University of Colorado School of Medicine. She was awarded a Boettcher Foundation Webb-Waring Early Career Investigator, received the Colorado School of Mines Inventor of the Year award in 2017, and in 2020 was awarded the Colorado School of Mines Faculty Excellence Award. Melissa is also CEO and Founder of a startup company GelSana Therapeutics, Inc.
Sustained localized presentation of RNA interfering molecules from in situ forming hydrogels to guide stem cell osteogenic differentiation.
Biomaterials Aug, 2014 | Pubmed ID: 24831973
Controlled delivery of antibodies from injectable hydrogels.
Materials science & engineering. C, Materials for biological applications Feb, 2016 | Pubmed ID: 26652435
Comparative Study of Poly (ε-Caprolactone) and Poly(Lactic-co-Glycolic Acid) -Based Nanofiber Scaffolds for pH-Sensing.
Pharmaceutical research Oct, 2016 | Pubmed ID: 27380188
Injectable and microporous scaffold of densely-packed, growth factor-encapsulating chitosan microgels.
Carbohydrate polymers Nov, 2016 | Pubmed ID: 27516331
Collagen and collagen-chondroitin sulfate scaffolds with uniaxially aligned pores for the biomimetic, three dimensional culture of trabecular meshwork cells.
Biotechnology and bioengineering Apr, 2017 | Pubmed ID: 27775151
Engineering Osteoinductive Biomaterials by Bioinspired Synthesis of Apatite Coatings on Collagen Hydrogels with Varied Pore Microarchitectures.
Tissue engineering. Part A 12, 2017 | Pubmed ID: 28622088
Regenerative Medicine Approaches for the Treatment of Pediatric Physeal Injuries.
Tissue engineering. Part B, Reviews 04, 2018 | Pubmed ID: 28830302
Cell-interactive alginate-chitosan biopolymer systems with tunable mechanics and antibody release rates.
Carbohydrate polymers Nov, 2017 | Pubmed ID: 28917928
Microgels: Modular, tunable constructs for tissue regeneration.
Acta biomaterialia 04, 2019 | Pubmed ID: 30769137
Imaging and Analysis of Cellular Locations in Three-Dimensional Tissue Models.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 06, 2019 | Pubmed ID: 30853032
Injectable, self-healable zwitterionic cryogels with sustained microRNA - cerium oxide nanoparticle release promote accelerated wound healing.
Acta biomaterialia 01, 2020 | Pubmed ID: 31726250
In vivo degradation rate of alginate-chitosan hydrogels influences tissue repair following physeal injury.
Journal of biomedical materials research. Part B, Applied biomaterials 08, 2020 | Pubmed ID: 32034881
Human trabecular meshwork cell behavior is influenced by collagen scaffold pore architecture and glycosaminoglycan composition.
Biotechnology and bioengineering 10, 2020 | Pubmed ID: 32589791
Anti-VEGF antibody delivered locally reduces bony bar formation following physeal injury in rats.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 08, 2021 | Pubmed ID: 33179297
Bioinspired Deposition-Conversion Synthesis of Tunable Calcium Phosphate Coatings on Polymeric Hydrogels.
ACS biomaterials science & engineering Sep, 2017 | Pubmed ID: 33440557
Tunable chitosan-calcium phosphate composites as cell-instructive dental pulp capping agents.
Journal of biomaterials science. Polymer edition 08, 2021 | Pubmed ID: 33941040
Topical gel-based biomaterials for the treatment of diabetic foot ulcers.
Acta biomaterialia 01, 2022 | Pubmed ID: 34728428
Photopolymerized Zwitterionic Hydrogels with a Sustained Delivery of Cerium Oxide Nanoparticle-miR146a Conjugate Accelerate Diabetic Wound Healing.
ACS applied bio materials Mar, 2022 | Pubmed ID: 35167263
A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies
Christopher B. Erickson1,
Nichole Shaw2,
Nancy Hadley-Miller2,
Michael S. Riederer3,
Melissa D. Krebs3,
Karin A. Payne4
1Department of Bioengineering, Department of Orthopedics, University of Colorado Anschutz Medical Campus,
2Department of Orthopedics, University of Colorado Anschutz Medical Campus,
3Department of Chemical & Biological Engineering, Colorado School of Mines,
4Department of Orthopedics, Gates Center for Regenerative Medicine, University of Colorado Anschutz Medical Campus
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