Department of Pharmacology and Physiology,
Department of Physics
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Detecting rearrangements of shaker and NaChBac in real-time with fluorescence spectroscopy in patch-clamped mammalian cells.
Biophysical journal Jun, 2004 | Pubmed ID: 15189893
Silicon chip-based patch-clamp electrodes integrated with PDMS microfluidics.
Biosensors & bioelectronics Oct, 2004 | Pubmed ID: 15494233
Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement.
Nature Aug, 2005 | Pubmed ID: 16094369
A hybrid approach to measuring electrical activity in genetically specified neurons.
Nature neuroscience Nov, 2005 | Pubmed ID: 16205716
Cell activation by ligands of the toll-like receptor and interleukin-1 receptor family depends on the function of the large-conductance potassium channel MaxiK in human macrophages.
Infection and immunity Jul, 2006 | Pubmed ID: 16790810
Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction.
The Journal of general physiology Nov, 2006 | Pubmed ID: 17043150
Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2006 | Pubmed ID: 17043236
Fluorescence detection of the movement of single KcsA subunits reveals cooperativity.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2008 | Pubmed ID: 19074286
[Single-channel fluorescence spectroscopy to study conformational changes of ion channels].
Medecine sciences : M/S Nov, 2009 | Pubmed ID: 19951670
An intersubunit interaction between S4-S5 linker and S6 is responsible for the slow off-gating component in Shaker K+ channels.
The Journal of biological chemistry Apr, 2010 | Pubmed ID: 20202932
Rapid topology probing using fluorescence spectroscopy in planar lipid bilayer: the pore-forming mechanism of the toxin Cry1Aa of Bacillus thuringiensis.
The Journal of general physiology Nov, 2010 | Pubmed ID: 20974771
Mode shift of the voltage sensors in Shaker K+ channels is caused by energetic coupling to the pore domain.
The Journal of general physiology May, 2011 | Pubmed ID: 21518834
Double mutant cycle analysis identified a critical leucine residue in the IIS4S5 linker for the activation of the Ca(V)2.3 calcium channel.
The Journal of biological chemistry Aug, 2011 | Pubmed ID: 21652722
Single molecule fluorescence study of the Bacillus thuringiensis toxin Cry1Aa reveals tetramerization.
The Journal of biological chemistry Dec, 2011 | Pubmed ID: 22006922
Automating single subunit counting of membrane proteins in mammalian cells.
The Journal of biological chemistry Oct, 2012 | Pubmed ID: 22930752
Mechanism of electromechanical coupling in voltage-gated potassium channels.
Frontiers in pharmacology , 2012 | Pubmed ID: 22988442
A limited 4 Å radial displacement of the S4-S5 linker is sufficient for internal gate closing in Kv channels.
The Journal of biological chemistry Nov, 2012 | Pubmed ID: 23019337
Dynamics of internal pore opening in K(V) channels probed by a fluorescent unnatural amino acid.
Proceedings of the National Academy of Sciences of the United States of America May, 2013 | Pubmed ID: 23630265
Do lipids show state-dependent affinity to the voltage-gated potassium channel KvAP?
The Journal of biological chemistry Jun, 2014 | Pubmed ID: 24742679
Reinitiation at non-canonical start codons leads to leak expression when incorporating unnatural amino acids.
Scientific reports Jul, 2015 | Pubmed ID: 26153354
A Disease Mutation Causing Episodic Ataxia Type I in the S1 Links Directly to the Voltage Sensor and the Selectivity Filter in Kv Channels.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2015 | Pubmed ID: 26338330
The Human Sodium-Glucose Cotransporter (hSGLT1) Is a Disulfide-Bridged Homodimer with a Re-Entrant C-Terminal Loop.
PloS one , 2016 | Pubmed ID: 27137918
Structure of anthrax lethal toxin prepore complex suggests a pathway for efficient cell entry.
The Journal of general physiology Oct, 2016 | Pubmed ID: 27670897
The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel.
eLife Oct, 2016 | Pubmed ID: 27710769
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