Robert Blelloch

Nuclear transplantation, embryonic stem cells and the potential for cell therapy.

Reprogramming of a melanoma genome by nuclear transplantation.

TRA-1/GLI controls development of somatic gonadal precursors in C. elegans.

Nuclear cloning of embryonal carcinoma cells.

Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus.

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal.

Generation of induced pluripotent stem cells in the absence of drug selection.

Regenerative medicine: short cut to cell replacement.

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs.

CompMoby: comparative MobyDick for detection of cis-regulatory motifs.

Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation.

Posttranscriptional crossregulation between Drosha and DGCR8.

Embryonic stem cell-specific microRNAs promote induced pluripotency.

Cell cycle regulation by MicroRNAs in embryonic stem cells.

Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure.

Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8.

Watching reprogramming in real time.

Journal club. A computational biologist looks at how mRNA length changes during development.

Opposing microRNA families regulate self-renewal in mouse embryonic stem cells.

MicroRNA function is globally suppressed in mouse oocytes and early embryos.

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes.

MicroRNAs control hepatocyte proliferation during liver regeneration.

Distinct requirements of microRNAs in NK cell activation, survival, and function.

PML-RAR{alpha} and Dnmt3a1 cooperate in vivo to promote acute promyelocytic leukemia.

miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma.

On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010.

Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients.

MicroRNA Regulation of Embryonic Stem Cell Self-Renewal and Differentiation.

Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition.

Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex.

Small RNAs in early mammalian development: from gametes to gastrulation.

Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells.

Cell cycle regulation by microRNAs in stem cells.

From microRNAs to targets: pathway discovery in cell fate transitions.

A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing.

MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells.

Dgcr8 controls neural crest cells survival in cardiovascular development.

microRNA induced transdifferentiation.