Institute of Physiological Chemistry and Pathobiochemistry
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Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1.
Molecular biology of the cell Oct, 2001 | Pubmed ID: 11598185
Rhodocetin antagonizes stromal tumor invasion in vitro and other alpha2beta1 integrin-mediated cell functions.
Matrix biology : journal of the International Society for Matrix Biology Nov, 2002 | Pubmed ID: 12475639
Interleukin (IL)-6 and IL-10 induce decorin mRNA in endothelial cells, but interaction with fibrillar collagen is essential for its translation.
The Journal of biological chemistry May, 2004 | Pubmed ID: 15016829
Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange.
The Journal of physiology Aug, 2005 | Pubmed ID: 15946960
The glycocalyx maintains a cell surface pH nanoenvironment crucial for integrin-mediated migration of human melanoma cells.
Pflugers Archiv : European journal of physiology Oct, 2009 | Pubmed ID: 19562366
Redox-relevant aspects of the extracellular matrix and its cellular contacts via integrins.
Antioxidants & redox signaling May, 2014 | Pubmed ID: 24040997
Two barriers or not? Dynamic force spectroscopy on the integrin α7β1 invasin complex.
Biophysical journal Dec, 2013 | Pubmed ID: 24359749
Preserved bioactivity and tunable release of a SDF1-GPVI bi-specific protein using photo-crosslinked PEGda hydrogels.
Biomaterials Aug, 2014 | Pubmed ID: 24875761
Vimocin and Vidapin, Cyclic KTS Peptides, Are Dual Antagonists of α1β1/α2β1 Integrins with Antiangiogenic Activity.
The Journal of pharmacology and experimental therapeutics Sep, 2014 | Pubmed ID: 24939421
Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis.
Circulation Feb, 2015 | Pubmed ID: 25520375
Vipegitide: a folded peptidomimetic partial antagonist of α2β1 integrin with antiplatelet aggregation activity.
Drug design, development and therapy , 2015 | Pubmed ID: 25609915
Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets.
The Journal of biological chemistry May, 2015 | Pubmed ID: 25767114
Role of Integrins α1β1 and α2β1 in Wound and Tumor Angiogenesis in Mice.
The American journal of pathology Nov, 2016 | Pubmed ID: 27639165
The binding capacity of α1β1-, α2β1- and α10β1-integrins depends on non-collagenous surface macromolecules rather than the collagens in cartilage fibrils.
Matrix biology : journal of the International Society for Matrix Biology Nov, 2017 | Pubmed ID: 28192200
Dramatic and concerted conformational changes enable rhodocetin to block α2β1 integrin selectively.
PLoS biology Jul, 2017 | Pubmed ID: 28704364
Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets.
The Journal of biological chemistry 09, 2017 | Pubmed ID: 28705934
CLEC-2 contributes to hemostasis independently of classical hemITAM signaling in mice.
Blood 11, 2017 | Pubmed ID: 28835437
Collateral Damage Intended-Cancer-Associated Fibroblasts and Vasculature Are Potential Targets in Cancer Therapy.
International journal of molecular sciences Nov, 2017 | Pubmed ID: 29112161
Direct Fibrinolytic Snake Venom Metalloproteinases Affecting Hemostasis: Structural, Biochemical Features and Therapeutic Potential.
Toxins Dec, 2017 | Pubmed ID: 29206190
The spatial molecular pattern of integrin recognition sites and their immobilization to colloidal nanobeads determine α2β1 integrin-dependent platelet activation.
Biomaterials 06, 2018 | Pubmed ID: 29567387
More than a syllable in fib-ROS-is: The role of ROS on the fibrotic extracellular matrix and on cellular contacts.
Molecular aspects of medicine 10, 2018 | Pubmed ID: 29596842
Significant Hypo-Responsiveness to GPVI and CLEC-2 Agonists in Pre-Term and Full-Term Neonatal Platelets and following Immune Thrombocytopenia.
Thrombosis and haemostasis 06, 2018 | Pubmed ID: 29695020
Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis.
Blood 09, 2018 | Pubmed ID: 29891536
Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice.
Blood 09, 2018 | Pubmed ID: 29898956
Snake venom components in medicine: From the symbolic rod of Asclepius to tangible medical research and application.
The international journal of biochemistry & cell biology 11, 2018 | Pubmed ID: 30261311
The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells.
Cancers Dec, 2018 | Pubmed ID: 30583482
Platelet membrane lipid rafts protein composition varies following GPVI and CLEC-2 receptors activation.
Journal of proteomics Mar, 2019 | Pubmed ID: 30677554
Signals of the Neuropilin-1-MET Axis and Cues of Mechanical Force Exertion Converge to Elicit Inflammatory Activation in Coherent Endothelial Cells.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2019 | Pubmed ID: 30692210
Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα.
Blood advances Feb, 2019 | Pubmed ID: 30700416
Neuropilins in the Context of Tumor Vasculature.
International journal of molecular sciences Feb, 2019 | Pubmed ID: 30717262
ELMO1 deficiency enhances platelet function.
Blood advances Feb, 2019 | Pubmed ID: 30787021
Structurally Robust and Functionally Highly Versatile-C-Type Lectin (-Related) Proteins in Snake Venoms.
Toxins 03, 2019 | Pubmed ID: 30823637
Comparison of the GPVI inhibitors losartan and honokiol.
Platelets Mar, 2019 | Pubmed ID: 30849265
The extracellular matrix in tumor progression and metastasis.
Clinical & experimental metastasis Jun, 2019 | Pubmed ID: 30972526
TULA-2 Deficiency Enhances Platelet Functional Responses to CLEC-2 Agonists.
TH open : companion journal to thrombosis and haemostasis Oct, 2018 | Pubmed ID: 31249969
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