Tomohiro Miyasaka

Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo.

Microtubule destruction induces tau liberation and its subsequent phosphorylation.

Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction.

Substrate ectodomain is critical for substrate preference and inhibition of γ-secretase.

The homologous carboxyl-terminal domains of microtubule-associated protein 2 and TAU induce neuronal dysfunction and have differential fates in the evolution of neurofibrillary tangles.

Immunostaining of oxidized DJ-1 in human and mouse brains.

Identification of key amino acids responsible for the distinct aggregation properties of microtubule-associated protein 2 and tau.

Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups.

Curcumin improves tau-induced neuronal dysfunction of nematodes.

The Role of the Carboxyl-Terminal Sequence of Tau and MAP2 in the Pathogenesis of Dementia.

Distinct deposition of amyloid-β species in brains with Alzheimer's disease pathology visualized with MALDI imaging mass spectrometry.

Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.

Imbalanced Expression of Tau and Tubulin Induces Neuronal Dysfunction in Models of Tauopathy.

Distribution of oxidized DJ-1 in Parkinson's disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin.

Distribution of endogenous normal tau in the mouse brain.

Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain.

Regulatory mechanisms for the axonal localization of tau protein in neurons.

Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs.

Inhibition of microtubule assembly competent tubulin synthesis leads to accumulation of phosphorylated tau in neuronal cell bodies.

The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection.

A potential defense mechanism against amyloid deposition in cerebellum.

Quantitative fractionation of tissue microtubules with distinct biochemical properties reflecting their stability and lability.

Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo.

Therapeutic effect of a novel curcumin derivative GT863 on a mouse model of amyotrophic lateral sclerosis.

Microtubule assembly by tau impairs endocytosis and neurotransmission via dynamin sequestration in Alzheimer's disease synapse model.

Quantum-dot-labeled synuclein seed assay identifies drugs modulating the experimental prion-like transmission.

The organization of microtubules and Tau in oligodendrocytes: Tau pathology in damaged oligodendrocytes.

Identification of Tau protein as a novel marker for maturation and pathological changes of oligodendrocytes.

The senile plaque: Morphological differences in APP knock-in mice brains by fixatives.

Mass Spectrometry Imaging in Alzheimer's Disease.