Center for Microbial Pathogenesis,
Nationwide Children's Hospital and the Department of Pediatrics,
Nationwide Children’s Hospital and the Department of Pediatrics,
Center for Microbial Pathogenesis, Nationwide Children's Hospital and the Department of Pediatrics,
Center for Microbial Pathogenesis, Nationwide Children’s Hospital and the Department of Pediatrics
Steven D. Goodman has not added Biography.
If you are Steven D. Goodman and would like to personalize this page please email our Author Liaison for assistance.
Biofilms can be dispersed by focusing the immune system on a common family of bacterial nucleoid-associated proteins.
Mucosal immunology Nov, 2011 | Pubmed ID: 21716265
Aberrant community architecture and attenuated persistence of uropathogenic Escherichia coli in the absence of individual IHF subunits.
PloS one , 2012 | Pubmed ID: 23133584
Targeting bacterial integration host factor to disrupt biofilms associated with cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society Jul, 2013 | Pubmed ID: 23168017
Antibodies directed against integration host factor mediate biofilm clearance from Nasopore.
The Laryngoscope Nov, 2013 | Pubmed ID: 23670606
Structural stability of Burkholderia cenocepacia biofilms is reliant on eDNA structure and presence of a bacterial nucleic acid binding protein.
PloS one , 2013 | Pubmed ID: 23799151
Evaluation of the kinetics and mechanism of action of anti-integration host factor-mediated disruption of bacterial biofilms.
Molecular microbiology Sep, 2014 | Pubmed ID: 25069521
Antibodies against the majority subunit of type IV Pili disperse nontypeable Haemophilus influenzae biofilms in a LuxS-dependent manner and confer therapeutic resolution of experimental otitis media.
Molecular microbiology Apr, 2015 | Pubmed ID: 25597921
DNABII proteins play a central role in UPEC biofilm structure.
Molecular microbiology Jun, 2015 | Pubmed ID: 25757804
Monoclonal antibodies against DNA-binding tips of DNABII proteins disrupt biofilms in vitro and induce bacterial clearance in vivo.
EBioMedicine Aug, 2016 | Pubmed ID: 27342872
Identification of biofilms in post-tympanostomy tube otorrhea.
The Laryngoscope 08, 2016 | Pubmed ID: 27426942
Transcutaneous Immunization with a Band-Aid Prevents Experimental Otitis Media in a Polymicrobial Model.
Clinical and vaccine immunology : CVI Jun, 2017 | Pubmed ID: 28381402
Nontypeable releases DNA and DNABII proteins via a T4SS-like complex and ComE of the type IV pilus machinery.
Proceedings of the National Academy of Sciences of the United States of America 08, 2017 | Pubmed ID: 28696280
Application of single nucleotide extension and MALDI-TOF mass spectrometry in proofreading and DNA repair assay.
DNA repair 01, 2018 | Pubmed ID: 29223016
The DNABII family of proteins is comprised of the only nucleoid associated proteins required for nontypeable Haemophilus influenzae biofilm structure.
MicrobiologyOpen Dec, 2017 | Pubmed ID: 29230970
Identification of essential biofilm proteins in middle ear fluids of otitis media with effusion patients.
The Laryngoscope 03, 2020 | Pubmed ID: 31021431
Antibodies against the DNABII protein integration host factor (IHF) inhibit sinus implant biofilms.
The Laryngoscope 06, 2020 | Pubmed ID: 31314141
The extracellular DNA lattice of bacterial biofilms is structurally related to Holliday junction recombination intermediates.
Proceedings of the National Academy of Sciences of the United States of America , | Pubmed ID: 31767757
Proofreading of single nucleotide insertion/deletion replication errors analyzed by MALDI-TOF mass spectrometry assay.
DNA repair 04, 2020 | Pubmed ID: 32036259
Immunization with a Biofilm-Disrupting Nontypeable Vaccine Antigen Did Not Alter the Gut Microbiome in Chinchillas, Unlike Oral Delivery of a Broad-Spectrum Antibiotic Commonly Used for Otitis Media.
mSphere 04, 2020 | Pubmed ID: 32295873
Targeting a bacterial DNABII protein with a chimeric peptide immunogen or humanised monoclonal antibody to prevent or treat recalcitrant biofilm-mediated infections.
EBioMedicine Sep, 2020 | Pubmed ID: 32651162
Measurement of uracil-DNA glycosylase activity by matrix assisted laser desorption/ionization time-of-flight mass spectrometry technique.
DNA repair 01, 2021 | Pubmed ID: 33254084
Nontypeable newly released (NRel) from biofilms by antibody-mediated dispersal antibody-mediated disruption are phenotypically distinct.
Biofilm Dec, 2020 | Pubmed ID: 33447823
Enhanced biofilm and extracellular matrix production by chronic carriage versus acute isolates of Salmonella Typhi.
PLoS pathogens 01, 2021 | Pubmed ID: 33465146
Escherichia coli Nissle 1917 administered as a dextranomar microsphere biofilm enhances immune responses against human rotavirus in a neonatal malnourished pig model colonized with human infant fecal microbiota.
PloS one , 2021 | Pubmed ID: 33592026
Humanized Anti-DNABII Fab Fragments Plus Ofloxacin Eradicated Biofilms in Experimental Otitis Media.
The Laryngoscope 10, 2021 | Pubmed ID: 33666254
The dental plaque biofilm matrix.
Periodontology 2000 06, 2021 | Pubmed ID: 33690911
in Its Biofilm State Improves Protection from Experimental Necrotizing Enterocolitis.
Nutrients Mar, 2021 | Pubmed ID: 33809097
The extracellular innate-immune effector HMGB1 limits pathogenic bacterial biofilm proliferation.
The Journal of clinical investigation 08, 2021 | Pubmed ID: 34396989
A Humanized Monoclonal Antibody Potentiates Killing of Diverse Biofilm-Forming Respiratory Tract Pathogens by Antibiotics.
Antimicrobial agents and chemotherapy 03, 2022 | Pubmed ID: 35007137
Bacterial Biofilms Utilize an Underlying Extracellular DNA Matrix Structure That Can Be Targeted for Biofilm Resolution.
Microorganisms Feb, 2022 | Pubmed ID: 35208922
Kang-Yi Su*,1,2,
Steven D. Goodman*,3,
Hung-Ming Lai1,
Rong-Syuan Yen1,
Wei-Yao Hu1,
Wern-Cherng Cheng2,
Liang-In Lin1,2,
Ya-Chien Yang1,2,
Woei-Horng Fang1,2
1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University,
2Department of Laboratory Medicine, National Taiwan University Hospital,
3Center for Microbial Pathogenesis, Nationwide Children's Hospital and the Department of Pediatrics, The Ohio State University
Hui-Lan Chang*,1,
Kang-Yi Su*,1,2,
Steven D. Goodman3,
Wern-Cherng Cheng2,
Liang-In Lin1,2,
Ya-Chien Yang1,2,
Sui-Yuan Chang1,2,
Woei-horng Fang1,2
1Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University,
2Department of Laboratory Medicine, National Taiwan University Hospital,
3Center for Microbial Pathogenesis, Nationwide Children’s Hospital and the Department of Pediatrics, The Ohio State University
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados