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Department of Cell and Developmental Biology,
Neuroscience Center,
Department of Cell and Developmental Biology, Neuroscience Center
Mohanish Deshmukh has not added Biography.
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Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2002 | Pubmed ID: 11756493
Multiple channel interactions explain the protection of sympathetic neurons from apoptosis induced by nerve growth factor deprivation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2002 | Pubmed ID: 11756494
Exogenous smac induces competence and permits caspase activation in sympathetic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2002 | Pubmed ID: 12223555
Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis.
The Journal of cell biology Nov, 2003 | Pubmed ID: 14623868
Stability and apoptotic activity of recombinant human cytochrome c.
Biochemical and biophysical research communications Dec, 2003 | Pubmed ID: 14680826
Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis.
The Journal of cell biology Oct, 2004 | Pubmed ID: 15504912
Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.
Molecular and cellular biology Dec, 2004 | Pubmed ID: 15542838
Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP.
The Journal of cell biology Dec, 2005 | Pubmed ID: 16344307
Enhanced sensitivity to cytochrome c-induced apoptosis mediated by PHAPI in breast cancer cells.
Cancer research Feb, 2006 | Pubmed ID: 16489023
Restricting apoptosis for postmitotic cell survival and its relevance to cancer.
Cell cycle (Georgetown, Tex.) Aug, 2006 | Pubmed ID: 16880745
微生物病原体引起的坏死性细胞死亡介导的 inflammasome 组件 CIAS1/cryopyrin/NLRP3 和 ASC。
Cell host & microbe Sep, 2007 | Pubmed ID: 18005730
Chromatin modification of Apaf-1 restricts the apoptotic pathway in mature neurons.
The Journal of cell biology Dec, 2007 | Pubmed ID: 18056406
Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18093951
Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c.
Nature cell biology Dec, 2008 | Pubmed ID: 19029908
Skeletal muscle differentiation evokes endogenous XIAP to restrict the apoptotic pathway.
PloS one , 2009 | Pubmed ID: 19333375
Lack of X-linked inhibitor of apoptosis protein leads to increased apoptosis and tissue loss following neonatal brain injury.
ASN neuro , 2009 | Pubmed ID: 19570023
miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis.
Genes & development Jan, 2011 | Pubmed ID: 21245165
Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice.
Human molecular genetics Jan, 2012 | Pubmed ID: 22262731
University of North Carolina
Adam J. Kole1,
Elizabeth R.W. Knight2,
Mohanish Deshmukh1
1Department of Cell and Developmental Biology, Neuroscience Center, University of North Carolina ,
2Curriculum in Neurobiology, Neuroscience Center, University of North Carolina
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