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Maisonneuve-Rosemont Hospital Research Center and Department of Medicine
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Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O.
Molecular cell May, 2014 | Pubmed ID: 24703950
The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.
The Journal of biological chemistry Nov, 2015 | Pubmed ID: 26416890
Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1.
Nature communications 10, 2018 | Pubmed ID: 30349006
University of Montréal
Louis Masclef*,1,
Uriarte Maxime*,1,
Oumaima Ahmed1,
Nadine Sen Nkwe1,
Haithem Barbour1,
Nicholas V.G. Iannantuono1,
Amina Boubekeur1,
Salima Daou1,2,
El Bachir Affar1,2
1Maisonneuve-Rosemont Hospital Research Center and Department of Medicine, University of Montréal,
2Lunenfeld-Tanenbaum Research Institute, Sinai Health System
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