J. David Barrass

Splicing goes global.

Yeast ntr1/spp382 mediates prp43 function in postspliceosomes.

prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast.

Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8.

Interaction of yeast eIF4G with spliceosome components: implications in pre-mRNA processing events.

Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome.

RiboSys, a high-resolution, quantitative approach to measure the in vivo kinetics of pre-mRNA splicing and 3'-end processing in Saccharomyces cerevisiae.

Splicing-dependent RNA polymerase pausing in yeast.

Kinetic analysis of pre-ribosome structure in vivo.

A splicing-dependent transcriptional checkpoint associated with prespliceosome formation.

Brr2p carboxy-terminal Sec63 domain modulates Prp16 splicing RNA helicase.

Cwc21p promotes the second step conformation of the spliceosome and modulates 3' splice site selection.

Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling.

A Nuclear Export Block Triggers the Decay of Newly Synthesized Polyadenylated RNA.

A fast and tuneable auxin-inducible degron for depletion of target proteins in budding yeast.