School of Pharmacy,
Faculty of Medical and Health Sciences,
School of Pharmacy, Faculty of Medical and Health Sciences
Dr Zimei Wu is an Associate Professor at the School of Pharmacy, The University of Auckland, New Zealand (NZ). She hold a MSc degree from China Pharmaceutical University and a PhD from University of Otago (NZ). In 1999, she came to School of Pharmacy, University of Otago as a visiting scholar where she later on commenced her PhD followed by postdoctoral research. In 2009, Dr Wu was appointed as a lecturer at School of Pharmacy, University of Auckland, where she teaches and researches in all aspects of pharmaceutical sciences. In the past 10 years she has focused on design and engineering of nano-vesicles such as liposomes, noisomes, and liposomes-exosome hybrids with biological functions to target disease hallmarks (receptors, transporters, low pH, redox potential), and understanding of cellular trafficking of nano-systems.
Dr Wu is the immediate Past President of NZ Chapter of Controlled Release Society (CRS), and serves on the Editorial Boards of Journal of Liposome Research and Pharmaceutical Development and Technology, Biomaterials Science etc, and has been a referee for more than 20 research journals.
Preparation, safety, pharmacokinetics, and pharmacodynamics of liposomes containing Brucea javanica oil.
AAPS PharmSciTech Jun, 2010 | Pubmed ID: 20490956
Absorption and tissue tolerance of ricobendazole in the presence of hydroxypropyl-beta-cyclodextrin following subcutaneous injection in sheep.
International journal of pharmaceutics Sep, 2010 | Pubmed ID: 20621175
Tissue compatibility and pharmacokinetics of three potential subcutaneous injectables for low-pH drug solutions.
The Journal of pharmacy and pharmacology Jul, 2010 | Pubmed ID: 20636875
Preparation and characterization of a lovastatin-loaded protein-free nanostructured lipid carrier resembling high-density lipoprotein and evaluation of its targeting to foam cells.
AAPS PharmSciTech Dec, 2011 | Pubmed ID: 21927961
In-situ phase transition from microemulsion to liquid crystal with the potential of prolonged parenteral drug delivery.
International journal of pharmaceutics Jul, 2012 | Pubmed ID: 22548845
Conjunctival and corneal tolerability assessment of ocular naltrexone niosomes and their ingredients on the hen's egg chorioallantoic membrane and excised bovine cornea models.
International journal of pharmaceutics Aug, 2012 | Pubmed ID: 22575752
Niosomes and discomes for ocular delivery of naltrexone hydrochloride: morphological, rheological, spreading properties and photo-protective effects.
International journal of pharmaceutics Aug, 2012 | Pubmed ID: 22595640
Advanced carrier systems in cosmetics and cosmeceuticals: a review.
Journal of cosmetic science , | Pubmed ID: 22682399
Development of an isocratic HPLC method for catechin quantification and its application to formulation studies.
Fitoterapia Jun, 2012 | Pubmed ID: 22735602
In-vitro prediction of bioavailability following extravascular injection of poorly soluble drugs: an insight into clinical failure and the role of delivery systems.
The Journal of pharmacy and pharmacology Oct, 2013 | Pubmed ID: 24028610
Metabolomic approach to evaluating adriamycin pharmacodynamics and resistance in breast cancer cells.
Metabolomics : Official journal of the Metabolomic Society , 2013 | Pubmed ID: 24039617
A study of microemulsions as prolonged-release injectables through in-situ phase transition.
Journal of controlled release : official journal of the Controlled Release Society Jan, 2014 | Pubmed ID: 24316265
Development of high-content gemcitabine PEGylated liposomes and their cytotoxicity on drug-resistant pancreatic tumour cells.
Pharmaceutical research Oct, 2014 | Pubmed ID: 24639234
Development of a gradient high performance liquid chromatography assay for simultaneous analysis of hydrophilic gemcitabine and lipophilic curcumin using a central composite design and its application in liposome development.
Journal of pharmaceutical and biomedical analysis Sep, 2014 | Pubmed ID: 24998672
Physicochemical characterization of asulacrine towards the development of an anticancer liposomal formulation via active drug loading: stability, solubility, lipophilicity and ionization.
International journal of pharmaceutics Oct, 2014 | Pubmed ID: 25079434
An investigation into the stability and sterility of citric acid solutions used for cough reflex testing.
Dysphagia Oct, 2014 | Pubmed ID: 25150508
Strategies to maximize liposomal drug loading for a poorly water-soluble anticancer drug.
Pharmaceutical research Apr, 2015 | Pubmed ID: 25355460
Physicochemical characterization of native glycyl-l-histidyl-l-lysine tripeptide for wound healing and anti-aging: a preformulation study for dermal delivery.
Pharmaceutical development and technology Mar, 2016 | Pubmed ID: 25384620
Enhanced pH-Responsiveness, Cellular Trafficking, Cytotoxicity and Long-circulation of PEGylated Liposomes with Post-insertion Technique Using Gemcitabine as a Model Drug.
Pharmaceutical research Jul, 2015 | Pubmed ID: 25663325
Critical appraisal of alternative irritation models: three decades of testing ophthalmic pharmaceuticals.
British medical bulletin Mar, 2015 | Pubmed ID: 25686845
Post-insertion of poloxamer 188 strengthened liposomal membrane and reduced drug irritancy and in vivo precipitation, superior to PEGylation.
Journal of controlled release : official journal of the Controlled Release Society Apr, 2015 | Pubmed ID: 25701612
A pre-clinical pharmacokinetic study in rats of three naturally occurring iridoid glycosides, Picroside-I, II and III, using a validated simultaneous HPLC-MS/MS assay.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Jul, 2015 | Pubmed ID: 25984965
Pharmacokinetics and tissue distribution of Aucubin, Ajugol and Catalpol in rats using a validated simultaneous LC-ESI-MS/MS assay.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Oct, 2015 | Pubmed ID: 26342167
Supercritical Fluid Technologies to Fabricate Proliposomes.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques , 2015 | Pubmed ID: 26670368
Synthesis of a bi-functional dendrimer-based nanovehicle co-modified with RGDyC and TAT peptides for neovascular targeting and penetration.
International journal of pharmaceutics Mar, 2016 | Pubmed ID: 26828670
Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: A review.
Biomaterials Apr, 2016 | Pubmed ID: 26871891
Development of Long-Circulating pH-Sensitive Liposomes to Circumvent Gemcitabine Resistance in Pancreatic Cancer Cells.
Pharmaceutical research 07, 2016 | Pubmed ID: 26964546
Reversal of lipophilic weak bases using pH gradient acidic centre liposomes: demonstration of effect in dabigatran-induced anticoagulation.
Clinical toxicology (Philadelphia, Pa.) Jun, 2016 | Pubmed ID: 27019991
Improving drug retention in liposomes by aging with the aid of glucose.
International journal of pharmaceutics May, 2016 | Pubmed ID: 27021465
Identification and characterization of in vivo metabolites of asulacrine using advanced mass spectrophotometry technique in combination with improved data mining strategy.
Journal of chromatography. A Apr, 2016 | Pubmed ID: 27040513
Injectable thermosensitive gelling delivery system for the sustained release of lidocaine.
Therapeutic delivery 06, 2016 | Pubmed ID: 27250538
Integrated scientific data bases review on asulacrine and associated toxicity.
Critical reviews in oncology/hematology Aug, 2016 | Pubmed ID: 27321375
Optimization of the formation of embedded multicellular spheroids of MCF-7 cells: How to reliably produce a biomimetic 3D model.
Analytical biochemistry Dec, 2016 | Pubmed ID: 27717854
pH-Sensitive PEGylated liposomes for delivery of an acidic dinitrobenzamide mustard prodrug: Pathways of internalization, cellular trafficking and cytotoxicity to cancer cells.
International journal of pharmaceutics Jan, 2017 | Pubmed ID: 27871834
A shell-crosslinked polymeric micelle system for pH/redox dual stimuli-triggered DOX on-demand release and enhanced antitumor activity.
Colloids and surfaces. B, Biointerfaces Apr, 2017 | Pubmed ID: 28063272
Cyclic-RGDyC functionalized liposomes for dual-targeting of tumor vasculature and cancer cells in glioblastoma: An in vitro boron neutron capture therapy study.
Oncotarget May, 2017 | Pubmed ID: 28402271
Redox-sensitive and hyaluronic acid functionalized liposomes for cytoplasmic drug delivery to osteosarcoma in animal models.
Journal of controlled release : official journal of the Controlled Release Society 09, 2017 | Pubmed ID: 28666726
Chitooligosaccharides Modified Reduction-Sensitive Liposomes: Enhanced Cytoplasmic Drug Delivery and Osteosarcomas-Tumor Inhibition in Animal Models.
Pharmaceutical research Oct, 2017 | Pubmed ID: 28726003
Liposome supported peritoneal dialysis in rat amitriptyline exposure with and without intravenous lipid emulsion.
Journal of liposome research Jun, 2019 | Pubmed ID: 29141481
Particle morphology: an important factor affecting drug delivery by nanocarriers into solid tumors.
Expert opinion on drug delivery 04, 2018 | Pubmed ID: 29264946
Optimization of Weight Ratio for DSPE-PEG/TPGS Hybrid Micelles to Improve Drug Retention and Tumor Penetration.
Pharmaceutical research 01, 2018 | Pubmed ID: 29302821
Biotinylated-lipid bilayer coated mesoporous silica nanoparticles for improving the bioavailability and anti-leukaemia activity of Tanshinone IIA.
Artificial cells, nanomedicine, and biotechnology , 2018 | Pubmed ID: 29374971
Multiseed liposomal drug delivery system using micelle gradient as driving force to improve amphiphilic drug retention and its anti-tumor efficacy.
Drug delivery Nov, 2018 | Pubmed ID: 29493300
Estrogen-functionalized liposomes grafted with glutathione-responsive sheddable chotooligosaccharides for the therapy of osteosarcoma.
Drug delivery Nov, 2018 | Pubmed ID: 29644882
PEG-Benzaldehyde-Hydrazone-Lipid Based PEG-Sheddable pH-Sensitive Liposomes: Abilities for Endosomal Escape and Long Circulation.
Pharmaceutical research May, 2018 | Pubmed ID: 29855807
The Influence of Tablet Formulation, Drug Concentration, and pH Modification on the Stability of Extemporaneously Compounded Levothyroxine Suspensions.
International journal of pharmaceutical compounding Mar-Apr, 2018 | Pubmed ID: 29877863
Advances in rectal drug delivery systems.
Pharmaceutical development and technology Dec, 2018 | Pubmed ID: 29888992
Characterization of a smart pH-cleavable PEG polymer towards the development of dual pH-sensitive liposomes.
International journal of pharmaceutics Sep, 2018 | Pubmed ID: 29981407
The effect of DSPE-PEG, cholesterol and drug incorporated in bilayer on the formation of discoidal micelles.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Dec, 2018 | Pubmed ID: 30236551
Using Technology in Pharmacy Education: Pharmacy Student Performance and Perspectives When Visual Aids Are Integrated Into Learning.
Frontiers in pharmacology , 2018 | Pubmed ID: 30319411
Magnetic extraction of toxin binding liposomes; a method to ameliorate drug toxicity? Preliminary in vitro/ in vivo study.
Nanomedicine (London, England) 12, 2018 | Pubmed ID: 30457425
ATP-Responsive Low-Molecular-Weight Polyethylenimine-Based Supramolecular Assembly via Host-Guest Interaction for Gene Delivery.
Biomacromolecules 01, 2019 | Pubmed ID: 30516950
Engineering of Bone- and CD44-Dual-Targeting Redox-Sensitive Liposomes for the Treatment of Orthotopic Osteosarcoma.
ACS applied materials & interfaces Feb, 2019 | Pubmed ID: 30682240
Liposome-Mediated Drug Delivery in Larval Zebrafish to Manipulate Macrophage Function.
Zebrafish Apr, 2019 | Pubmed ID: 30724716
Can intracellular drug delivery using hyaluronic acid functionalised pH-sensitive liposomes overcome gemcitabine resistance in pancreatic cancer?
Journal of controlled release : official journal of the Controlled Release Society Jul, 2019 | Pubmed ID: 31096017
Optimisation of glutathione conjugation to liposomes quantified with a validated HPLC assay.
International journal of pharmaceutics Aug, 2019 | Pubmed ID: 31229530
Drug stability testing and formulation strategies.
Pharmaceutical development and technology 12, 2018 | Pubmed ID: 31284808
Dual pH-sensitive liposomes with low pH-triggered sheddable PEG for enhanced tumor-targeted drug delivery.
Nanomedicine (London, England) 08, 2019 | Pubmed ID: 31355712
Exploration of the antibiotic potentiating activity of indolglyoxylpolyamines.
European journal of medicinal chemistry Dec, 2019 | Pubmed ID: 31550659
Simple and reliable extraction and a validated high performance liquid chromatographic assay for quantification of amoxicillin from plasma.
Journal of chromatography. A Jan, 2020 | Pubmed ID: 31627968
Novel Cell-Penetrating Peptide Conjugated Proteasome Inhibitors: Anticancer and Antifungal Investigations.
Journal of medicinal chemistry Jan, 2020 | Pubmed ID: 31801019
Size-adaptable and ligand (biotin)-sheddable nanocarriers equipped with avidin scavenging technology for deep tumor penetration and reduced toxicity.
Journal of controlled release : official journal of the Controlled Release Society Jan, 2020 | Pubmed ID: 31978442
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