Moshe Elkabets

Effects of micro-environment- and malignant cell-derived interleukin-1 in carcinogenesis, tumour invasiveness and tumour-host interactions.

The involvement of IL-1 in tumorigenesis, tumor invasiveness, metastasis and tumor-host interactions.

Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors.

Host-derived interleukin-1alpha is important in determining the immunogenicity of 3-methylcholantrene tumor cells.

Differences in the sialylation patterns of membrane stress proteins in chemical carcinogen-induced tumors developed in BALB/c and IL-1alpha deficient mice.

Targeting of polymeric nanoparticles to lung metastases by surface-attachment of YIGSR peptide from laminin.

Sialylation of 3-methylcholanthrene-induced fibrosarcoma determines antitumor immune responses during immunoediting.

IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function.

Microenvironment-derived IL-1 and IL-17 interact in the control of lung metastasis.

The natural cytotoxicity receptor 1 contribution to early clearance of Streptococcus pneumoniae and to natural killer-macrophage cross talk.

Unique Versus Redundant Functions of IL-1α and IL-1β in the Tumor Microenvironment.

Molecular Pathways: AXL, a Membrane Receptor Mediator of Resistance to Therapy.

Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice.

P-selectin is a nanotherapeutic delivery target in the tumor microenvironment.

PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.

Enhanced ZnR/GPR39 Activity in Breast Cancer, an Alternative Trigger of Signaling Leading to Cell Growth.

Methods to Study the Role of Progranulin in the Tumor Microenvironment.

IGF1R upregulation confers resistance to isoform-specific inhibitors of PI3K in PIK3CA-driven ovarian cancer.

MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer.

High-Throughput Screening Identified Compounds Sensitizing Tumor Cells to Glucose Starvation in Culture and VEGF Inhibitors In Vivo.

Tumor Tissue Explant Culture of Patient-Derived Xenograft as Potential Prioritization Tool for Targeted Therapy.

Repression of AXL expression by AP-1/JNK blockage overcomes resistance to PI3Ka therapy.

The long noncoding RNA TP73-AS1 promotes tumorigenicity of medulloblastoma cells.

c-Met as a new marker of cellular senescence.

Inhibition of the NKp44-PCNA Immune Checkpoint Using a mAb to PCNA.

Adaptive Responses to Monotherapy in Head and Neck Cancer: Interventions for Rationale-Based Therapeutic Combinations.

Potential oncogenic roles of mutant-p53-derived exosomes in the tumor-host interaction of head and neck cancers.