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Department of Physiology and Pharmacology
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Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice.
Molecular medicine (Cambridge, Mass.) Mar, 2015 | Pubmed ID: 25365546
Targeted Deletion of Autophagy Genes Atg5 or Atg7 in the Chondrocytes Promotes Caspase-Dependent Cell Death and Leads to Mild Growth Retardation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Dec, 2015 | Pubmed ID: 26077727
Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
Autophagy , 2015 | Pubmed ID: 26259639
Targeted deletion of Atg5 in chondrocytes promotes age-related osteoarthritis.
Annals of the rheumatic diseases Mar, 2016 | Pubmed ID: 26438374
Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 03, 2017 | Pubmed ID: 27965322
Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage.
eLife 04, 2017 | Pubmed ID: 28414273
Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered.
Bone reports Jun, 2018 | Pubmed ID: 29955624
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate.
Nature 03, 2019 | Pubmed ID: 30814736
New insights into niclosamide action: autophagy activation in colorectal cancer.
The Biochemical journal Mar, 2019 | Pubmed ID: 30842311
Karolinska Institutet
Karolinska University Hospital
Baoyi Zhou1,
Marketa Kaucka1,
Andrei S. Chagin1,2,
Phillip T. Newton1,3
1Department of Physiology and Pharmacology, Karolinska Institutet,
2Institute for Regenerative Medicine, Sechenov First Moscow State Medical University (Sechenov University),
3Department of Women's and Children's Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital
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