David H. Wagner

Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes.

Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery.

Peripheral CD4loCD40+ auto-aggressive T cell expansion during insulin-dependent diabetes mellitus.

Re-shaping the T cell repertoire: TCR editing and TCR revision for good and for bad.

A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes.

An analytical workflow for investigating cytokine profiles.

High distribution of CD40 and TRAF2 in Th40 T cell rafts leads to preferential survival of this auto-aggressive population in autoimmunity.

Disruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T cells promotes diabetes.

CD40 on NOD CD4 T cells contributes to their activation and pathogenicity.

CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunity.

The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation.

CD40 engagement of CD4(+) CD40(+) T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance.