Department of Psychological and Brain Sciences,
Gill Center for Biomolecular Research,
Department of Psychological and Brain Sciences, Gill Center for Biomolecular Research
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Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area.
Neuropharmacology Jan, 2008 | Pubmed ID: 17655884
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
American journal of physiology. Heart and circulatory physiology Oct, 2007 | Pubmed ID: 17660390
From active ingredients to the discovery of the targets: the cannabinoid receptors.
Chemistry & biodiversity Aug, 2007 | Pubmed ID: 17712815
Understanding cannabinoid psychoactivity with mouse genetic models.
PLoS biology Oct, 2007 | Pubmed ID: 17927451
Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2008 | Pubmed ID: 18234884
Regulation of CB1 cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism.
Journal of neurochemistry Jul, 2008 | Pubmed ID: 18331587
Signaling via CNS cannabinoid receptors.
Molecular and cellular endocrinology Apr, 2008 | Pubmed ID: 18336996
Cannabinoid receptors: where they are and what they do.
Journal of neuroendocrinology May, 2008 | Pubmed ID: 18426493
Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats.
American journal of physiology. Gastrointestinal and liver physiology Jul, 2008 | Pubmed ID: 18483180
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2008 | Pubmed ID: 18562289
Wiring and firing neuronal networks: endocannabinoids take center stage.
Current opinion in neurobiology Jun, 2008 | Pubmed ID: 18801434
Building a new conceptual framework for receptor heteromers.
Nature chemical biology Mar, 2009 | Pubmed ID: 19219011
Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia.
The European journal of neuroscience May, 2009 | Pubmed ID: 19453631
Cannabinoid CB1 receptor-dependent long-term depression in autaptic excitatory neurons.
Journal of neurophysiology Aug, 2009 | Pubmed ID: 19494194
Cannabinoid signaling in inhibitory autaptic hippocampal neurons.
Neuroscience Sep, 2009 | Pubmed ID: 19501632
Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Dec, 2009 | Pubmed ID: 19675536
Get stoned in GABAergic synapses.
Nature neuroscience Sep, 2009 | Pubmed ID: 19710646
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons.
Molecular pharmacology Dec, 2009 | Pubmed ID: 19767452
The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2009 | Pubmed ID: 19805329
Characterization of cannabinoid-1 receptors in the locus coeruleus: relationship with mu-opioid receptors.
Brain research Feb, 2010 | Pubmed ID: 19931229
Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells.
Diabetes Feb, 2010 | Pubmed ID: 19933999
CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.
Cardiovascular research Mar, 2010 | Pubmed ID: 19942623
Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat.
Brain research bulletin Apr, 2010 | Pubmed ID: 20097273
JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist.
British journal of pharmacology Jun, 2010 | Pubmed ID: 20100276
Differential effects of CB(1) neutral antagonists and inverse agonists on gastrointestinal motility in mice.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society Jul, 2010 | Pubmed ID: 20180825
Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gamma.
The Journal of biological chemistry Jun, 2010 | Pubmed ID: 20410309
Alterations in the hippocampal endocannabinoid system in diet-induced obese mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2010 | Pubmed ID: 20445053
CB2: a cannabinoid receptor with an identity crisis.
British journal of pharmacology Jun, 2010 | Pubmed ID: 20590558
Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans.
Epilepsia Jul, 2010 | Pubmed ID: 20618415
Architecture of cannabinoid signaling in mouse retina.
The Journal of comparative neurology Sep, 2010 | Pubmed ID: 20653038
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.
Nature neuroscience Aug, 2010 | Pubmed ID: 20657592
Endocannabinoid involvement in endometriosis.
Pain Dec, 2010 | Pubmed ID: 20833475
Laserspray ionization, a new method for protein analysis directly from tissue at atmospheric pressure with ultrahigh mass resolution and electron transfer dissociation.
Molecular & cellular proteomics : MCP Feb, 2011 | Pubmed ID: 20855542
Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2010 | Pubmed ID: 20962221
WNT signaling in activated microglia is proinflammatory.
Glia Jan, 2011 | Pubmed ID: 20967887
Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections.
The European journal of neuroscience Sep, 2010 | Pubmed ID: 21050275
Presynaptic CB1 receptors regulate synaptic plasticity at cerebellar parallel fiber synapses.
Journal of neurophysiology Feb, 2011 | Pubmed ID: 21084685
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis.
BMC genomics Jan, 2011 | Pubmed ID: 21214938
CP47,497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB(1) cannabinoid receptor agonists.
European journal of pharmacology Jun, 2011 | Pubmed ID: 21333643
Imaging mass spectrometry in transmission geometry.
Rapid communications in mass spectrometry : RCM Mar, 2011 | Pubmed ID: 21337644
Molecular reorganization of endocannabinoid signalling in Alzheimer's disease.
Brain : a journal of neurology Apr, 2011 | Pubmed ID: 21459826
Δ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundity.
British journal of pharmacology Apr, 2012 | Pubmed ID: 21615727
The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment.
Inflammatory bowel diseases Aug, 2011 | Pubmed ID: 21744421
Molecular model of cannabis sensitivity in developing neuronal circuits.
Trends in pharmacological sciences Sep, 2011 | Pubmed ID: 21757242
Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2011 | Pubmed ID: 21775596
Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2011 | Pubmed ID: 21994376
The CB1 cannabinoid receptor C-terminus regulates receptor desensitization in autaptic hippocampal neurones.
British journal of pharmacology Apr, 2012 | Pubmed ID: 22014214
Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones.
British journal of pharmacology Apr, 2012 | Pubmed ID: 22014238
Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands.
Molecular pharmacology Feb, 2012 | Pubmed ID: 22064678
Quinpirole elicits differential in vivo changes in the pre- and postsynaptic distributions of dopamine D₂ receptors in mouse striatum: relation to cannabinoid-1 (CB₁) receptor targeting.
Psychopharmacology May, 2012 | Pubmed ID: 22160162
CB₂: therapeutic target-in-waiting.
Progress in neuro-psychopharmacology & biological psychiatry Jul, 2012 | Pubmed ID: 22197668
Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society Mar, 2012 | Pubmed ID: 22235973
Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy.
Diabetes Mar, 2012 | Pubmed ID: 22315315
Differential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats.
Glia May, 2012 | Pubmed ID: 22573306
CB₂ cannabinoid receptors inhibit synaptic transmission when expressed in cultured autaptic neurons.
Neuropharmacology Sep, 2012 | Pubmed ID: 22579668
A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation.
eNeuro Jul-Aug, 2016 | Pubmed ID: 27517090
Presynaptic CB(1) cannabinoid receptors control frontocortical serotonin and glutamate release--species differences.
Neurochemistry international Jul, 2012 | Pubmed ID: 22609378
Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons.
Brain structure & function May, 2013 | Pubmed ID: 22618437
Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2012 | Pubmed ID: 22787031
Cannabinoid-1 receptors in the mouse ventral pallidum are targeted to axonal profiles expressing functionally opposed opioid peptides and contacting N-acylphosphatidylethanolamine-hydrolyzing phospholipase D terminals.
Neuroscience Dec, 2012 | Pubmed ID: 22863674
Laserspray ionization imaging of multiply charged ions using a commercial vacuum MALDI ion source.
Analytical chemistry Nov, 2012 | Pubmed ID: 23009673
Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome.
Nature communications , 2012 | Pubmed ID: 23011134
Brain CB₁ receptor expression following lipopolysaccharide-induced inflammation.
Neuroscience Dec, 2012 | Pubmed ID: 23041513
Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2012 | Pubmed ID: 23055515
Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models.
The European journal of neuroscience Feb, 2013 | Pubmed ID: 23167744
CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling.
Nature neuroscience Apr, 2013 | Pubmed ID: 23502535
Cannabinoid receptors are widely expressed in goldfish: molecular cloning of a CB2-like receptor and evaluation of CB1 and CB2 mRNA expression profiles in different organs.
Fish physiology and biochemistry Oct, 2013 | Pubmed ID: 23504102
GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.
PloS one , 2013 | Pubmed ID: 23565223
Fmr1 deletion enhances and ultimately desensitizes CB(1) signaling in autaptic hippocampal neurons.
Neurobiology of disease Aug, 2013 | Pubmed ID: 23578490
A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice.
Neuropharmacology Aug, 2013 | Pubmed ID: 23603203
Diacylglycerol lipaseα (DAGLα) and DAGLβ cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons.
Molecular pharmacology Aug, 2013 | Pubmed ID: 23748223
Two novel mutations in ABHD12: expansion of the mutation spectrum in PHARC and assessment of their functional effects.
Human mutation Dec, 2013 | Pubmed ID: 24027063
CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release.
The Journal of biological chemistry Nov, 2013 | Pubmed ID: 24089517
Mastering tricyclic ring systems for desirable functional cannabinoid activity.
European journal of medicinal chemistry Nov, 2013 | Pubmed ID: 24125850
Impaired fear memory specificity associated with deficient endocannabinoid-dependent long-term plasticity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jun, 2014 | Pubmed ID: 24457285
Gβ₂ mimics activation kinetic slowing of CaV2.2 channels by noradrenaline in rat sympathetic neurons.
Biochemical and biophysical research communications Feb, 2014 | Pubmed ID: 24513289
The mismatch negativity: a translational probe of auditory processing in cannabis users.
Biological psychiatry Mar, 2014 | Pubmed ID: 24560430
Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses.
Neuron Mar, 2014 | Pubmed ID: 24607231
Mutation of putative GRK phosphorylation sites in the cannabinoid receptor 1 (CB1R) confers resistance to cannabinoid tolerance and hypersensitivity to cannabinoids in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2014 | Pubmed ID: 24719095
Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal.
Biological psychiatry Mar, 2015 | Pubmed ID: 24853387
Transmission geometry laserspray ionization vacuum using an atmospheric pressure inlet.
Analytical chemistry Jul, 2014 | Pubmed ID: 24896880
Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1.
Nature communications Aug, 2014 | Pubmed ID: 25081814
CB2 Cannabinoid receptors as a therapeutic target-what does the future hold?
Molecular pharmacology Oct, 2014 | Pubmed ID: 25106425
Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies.
Nature reviews. Neuroscience Dec, 2014 | Pubmed ID: 25409697
Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms.
Hepatology (Baltimore, Md.) May, 2015 | Pubmed ID: 25580584
Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation.
Molecular pharmacology Apr, 2015 | Pubmed ID: 25657338
CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain.
Molecular pharmacology Jul, 2015 | Pubmed ID: 25904556
Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor.
ACS chemical neuroscience Aug, 2015 | Pubmed ID: 25978068
An animal model of female adolescent cannabinoid exposure elicits a long-lasting deficit in presynaptic long-term plasticity.
Neuropharmacology Dec, 2015 | Pubmed ID: 25979486
Cannabinoid-induced chemotaxis in bovine corneal epithelial cells.
Investigative ophthalmology & visual science May, 2015 | Pubmed ID: 26024113
Tolerance to the antinociceptive effects of chronic morphine requires c-Jun N-terminal kinase.
Molecular pain Jun, 2015 | Pubmed ID: 26065412
Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memory.
Neurobiology of disease Oct, 2015 | Pubmed ID: 26093170
Ultrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons.
Neuroscience Sep, 2015 | Pubmed ID: 26162236
Aiming for allosterism: Evaluation of allosteric modulators of CB1 in a neuronal model.
Pharmacological research Sep, 2015 | Pubmed ID: 26211948
Drug detection and quantification directly from tissue using novel ionization methods for mass spectrometry.
European journal of mass spectrometry (Chichester, England) , 2015 | Pubmed ID: 26307700
Distribution of the Endocannabinoid System in the Central Nervous System.
Handbook of experimental pharmacology , 2015 | Pubmed ID: 26408158
An Introduction to the Endogenous Cannabinoid System.
Biological psychiatry Apr, 2016 | Pubmed ID: 26698193
Role of GPR55 during Axon Growth and Target Innervation.
eNeuro Sep-Oct, 2015 | Pubmed ID: 26730399
Stress induces analgesia via orexin 1 receptor-initiated endocannabinoid/CB1 signaling in the mouse periaqueductal gray.
Neuropharmacology 06, 2016 | Pubmed ID: 26907809
Matrix-Assisted Ionization on a Portable Mass Spectrometer: Analysis Directly from Biological and Synthetic Materials.
Analytical chemistry 11, 2016 | Pubmed ID: 26938428
Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain.
Biochimica et biophysica acta Jun, 2016 | Pubmed ID: 26956082
Cannabinoids Occlude the HIV-1 Tat-Induced Decrease in GABAergic Neurotransmission in Prefrontal Cortex Slices.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 06, 2016 | Pubmed ID: 26993829
Mechanisms of Biased β-Arrestin-Mediated Signaling Downstream from the Cannabinoid 1 Receptor.
Molecular pharmacology 06, 2016 | Pubmed ID: 27009233
A broad-based study on hyphenating new ionization technologies with MS/MS for PTMs and tissue characterization.
Proteomics 06, 2016 | Pubmed ID: 27093917
Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain.
Pharmacological research 08, 2016 | Pubmed ID: 27109320
Where's my entourage? The curious case of 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol.
Pharmacological research 08, 2016 | Pubmed ID: 27117667
A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase.
Molecular pain , 2016 | Pubmed ID: 27178246
Functional Selectivity of CB2 Cannabinoid Receptor Ligands at a Canonical and Noncanonical Pathway.
The Journal of pharmacology and experimental therapeutics 08, 2016 | Pubmed ID: 27194477
Hierarchical glucocorticoid-endocannabinoid interplay regulates the activation of the nucleus accumbens by insulin.
Brain research bulletin Jun, 2016 | Pubmed ID: 27208730
Western Blotting of the Endocannabinoid System.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 27245910
Quantitation of Plasma Membrane (G Protein-Coupled) Receptor Trafficking in Cultured Cells.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 27245911
Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons.
Nature communications 07, 2016 | Pubmed ID: 27448020
Mice Expressing a "Hyper-Sensitive" Form of the Cannabinoid Receptor 1 (CB1) Are Neither Obese Nor Diabetic.
PloS one , 2016 | Pubmed ID: 27501235
Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk.
Scientific reports Sep, 2016 | Pubmed ID: 27653550
Novel indole-based compounds that differentiate alkylindole-sensitive receptors from cannabinoid receptors and microtubules: Characterization of their activity on glioma cell migration.
Pharmacological research 01, 2017 | Pubmed ID: 27832960
Two Janus Cannabinoids That Are Both CB2 Agonists and CB1 Antagonists.
The Journal of pharmacology and experimental therapeutics Feb, 2017 | Pubmed ID: 27927913
Inflammation of peripheral tissues and injury to peripheral nerves induce differing effects in the expression of the calcium-sensitive N-arachydonoylethanolamine-synthesizing enzyme and related molecules in rat primary sensory neurons.
The Journal of comparative neurology Jun, 2017 | Pubmed ID: 27997038
Endocannabinoid signalling modulates susceptibility to traumatic stress exposure.
Nature communications 03, 2017 | Pubmed ID: 28348378
Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis.
JCI insight Apr, 2017 | Pubmed ID: 28422760
Mice expressing a "hyper-sensitive" form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption.
PloS one , 2017 | Pubmed ID: 28426670
Inflammatory and Neuropathic Nociception is Preserved in GPR55 Knockout Mice.
Scientific reports 04, 2017 | Pubmed ID: 28428628
Endocannabinoid signaling in hypothalamic circuits regulates arousal from general anesthesia in mice.
The Journal of clinical investigation Jun, 2017 | Pubmed ID: 28463228
Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities.
Neuropharmacology Sep, 2017 | Pubmed ID: 28527758
Cannabinoid CB Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB Mechanism that is Independent of CB Receptors in Mice.
The Journal of pharmacology and experimental therapeutics 08, 2017 | Pubmed ID: 28592614
A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner.
Investigative ophthalmology & visual science 06, 2017 | Pubmed ID: 28593245
Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse.
Journal of neurochemistry 08, 2017 | Pubmed ID: 28608535
Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence.
Biological psychiatry 11, 2018 | Pubmed ID: 28823711
Chronic Adolescent Δ-Tetrahydrocannabinol Treatment of Male Mice Leads to Long-Term Cognitive and Behavioral Dysfunction, Which Are Prevented by Concurrent Cannabidiol Treatment.
Cannabis and cannabinoid research , 2017 | Pubmed ID: 29098186
Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy.
Diabetes, obesity & metabolism 03, 2018 | Pubmed ID: 29106063
Enantiomer-specific positive allosteric modulation of CB signaling in autaptic hippocampal neurons.
Pharmacological research 03, 2018 | Pubmed ID: 29158048
Synthesis of Photoswitchable Δ-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling.
Journal of the American Chemical Society 12, 2017 | Pubmed ID: 29161035
Slowly Signaling G Protein-Biased CB Cannabinoid Receptor Agonist LY2828360 Suppresses Neuropathic Pain with Sustained Efficacy and Attenuates Morphine Tolerance and Dependence.
Molecular pharmacology 02, 2018 | Pubmed ID: 29192123
Endocannabinoid-Specific Impairment in Synaptic Plasticity in Striatum of Huntington's Disease Mouse Model.
The Journal of neuroscience : the official journal of the Society for Neuroscience 01, 2018 | Pubmed ID: 29192125
GPR55 regulates intraepithelial lymphocyte migration dynamics and susceptibility to intestinal damage.
Science immunology 12, 2017 | Pubmed ID: 29222090
Δ-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult.
Biochimica et biophysica acta. Molecular and cell biology of lipids May, 2018 | Pubmed ID: 29408467
Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior.
Biological psychiatry 08, 2018 | Pubmed ID: 29458998
Short-Term Genetic Selection for Adolescent Locomotor Sensitivity to Delta9-Tetrahydrocannabinol (THC).
Behavior genetics 05, 2018 | Pubmed ID: 29550900
Cannabidiol Inhibits Endocannabinoid Signaling in Autaptic Hippocampal Neurons.
Molecular pharmacology 07, 2018 | Pubmed ID: 29669714
Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure.
Pharmaceuticals (Basel, Switzerland) May, 2018 | Pubmed ID: 29786643
Analysis of Endocannabinoid System in Rat Testis During the First Spermatogenetic Wave.
Frontiers in endocrinology , 2018 | Pubmed ID: 29896156
Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation.
Neuropharmacology 09, 2018 | Pubmed ID: 29981335
Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS.
Neuropharmacology 10, 2018 | Pubmed ID: 30114402
( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.
Journal of medicinal chemistry 10, 2018 | Pubmed ID: 30196704
Sex-dependent effects of in utero cannabinoid exposure on cortical function.
eLife 09, 2018 | Pubmed ID: 30201092
Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray.
Proceedings of the National Academy of Sciences of the United States of America 11, 2018 | Pubmed ID: 30348772
Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal.
Molecular pharmacology 02, 2019 | Pubmed ID: 30504240
Cannabidiol's Upregulation of -acyl Ethanolamines in the Central Nervous System Requires -acyl Phosphatidyl Ethanolamine-Specific Phospholipase D.
Cannabis and cannabinoid research , 2018 | Pubmed ID: 30515459
Broad and Region-Specific Impacts of the Synthetic Cannabinoid CP 55,940 in Adolescent and Adult Female Mouse Brains.
Frontiers in molecular neuroscience , 2018 | Pubmed ID: 30542263
GPR55 controls functional differentiation of self-renewing epithelial progenitors for salivation.
JCI insight 02, 2019 | Pubmed ID: 30830860
Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures.
International journal of molecular sciences Mar, 2019 | Pubmed ID: 30871175
Evidence for a GPR18 Role in Chemotaxis, Proliferation, and the Course of Wound Closure in the Cornea.
Cornea Jul, 2019 | Pubmed ID: 30969262
Ultrastructural localization of cannabinoid CB1 and mGluR5 receptors in the prefrontal cortex and amygdala.
The Journal of comparative neurology Nov, 2019 | Pubmed ID: 31008528
Self-administration of edible Δ-tetrahydrocannabinol and associated behavioral effects in mice.
Drug and alcohol dependence 06, 2019 | Pubmed ID: 31029878
Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype.
Frontiers in molecular neuroscience , 2019 | Pubmed ID: 31213981
Cannabinoid receptor-mediated modulation of inhibitory inputs to mitral cells in the main olfactory bulb.
Journal of neurophysiology 08, 2019 | Pubmed ID: 31215302
Chronic adolescent exposure to ∆9-tetrahydrocannabinol decreases NMDA current and extrasynaptic plasmalemmal density of NMDA GluN1 subunits in the prelimbic cortex of adult male mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 01, 2020 | Pubmed ID: 31323660
Inhibitory Control Deficits Associated with Upregulation of CBR in the HIV-1 Tat Transgenic Mouse Model of Hand.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Dec, 2019 | Pubmed ID: 31372820
Cannabinoid Exposure via Lactation in Rats Disrupts Perinatal Programming of the Gamma-Aminobutyric Acid Trajectory and Select Early-Life Behaviors.
Biological psychiatry Apr, 2020 | Pubmed ID: 31653479
Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy.
Molecular psychiatry 01, 2020 | Pubmed ID: 31735910
Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators.
Journal of medicinal chemistry Jan, 2020 | Pubmed ID: 31756109
c-Jun N terminal kinase signaling pathways mediate cannabinoid tolerance in an agonist-specific manner.
Neuropharmacology 03, 2020 | Pubmed ID: 31758947
Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos.
International journal of molecular sciences Dec, 2019 | Pubmed ID: 31881740
Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening.
Neuron Mar, 2020 | Pubmed ID: 31948734
One-Stop Microfluidic Assembly of Human Brain Organoids To Model Prenatal Cannabis Exposure.
Analytical chemistry Mar, 2020 | Pubmed ID: 32070103
Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice.
Science advances 02, 2020 | Pubmed ID: 32095523
A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System.
iScience Mar, 2020 | Pubmed ID: 32143135
Components of Endocannabinoid Signaling System are Expressed in the Perinatal Mouse Cerebellum and Required for its Normal Development.
eNeuro Mar, 2020 | Pubmed ID: 32179579
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