Yan Chai

[Distribution of organochlorine pesticides in surface sediments from the middle and lower reaches of the Yellow River].

Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I.

Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.

Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.

An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.

The crystal structure of Zika virus NS5 reveals conserved drug targets.

Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab.

Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures.

Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope.

Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies.

The Postfusion Structure of the Heartland Virus Gc Glycoprotein Supports Taxonomic Separation of the Bunyaviral Families Phenuiviridae and Hantaviridae.

Two classes of protective antibodies against Pseudorabies virus variant glycoprotein B: Implications for vaccine design.

Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses.

Structural and functional insights into MCR-2 mediated colistin resistance.

An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I.

Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.

Glycosylation-independent binding of monoclonal antibody toripalimab to FG loop of PD-1 for tumor immune checkpoint therapy.

Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.

The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy.

Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein.

Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development.

Divergent Peptide Presentations of HLA-A30 Alleles Revealed by Structures With Pathogen Peptides.

Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.

Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target.

The identification of a CD47-blocking "hotspot" and design of a CD47/PD-L1 dual-specific antibody with limited hemagglutination.

The structural basis of African swine fever virus pA104R binding to DNA and its inhibition by stilbene derivatives.

Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1.

Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.

N-glycosylation of PD-1 promotes binding of camrelizumab.

Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses.

A broadly protective antibody that targets the flavivirus NS1 protein.