an-ex-vivo-assay-to-study-candida-albicans-hyphal-morphogenesis

An Ex vivo Assay to Study <em>Candida albicans</em> Hyphal Morphogenesis in the Gastrointestinal Tract

Candida albicans hyphal morphogenesis in the gastrointestinal (GI) tract is tightly controlled by various environmental signals, and plays an important ...

Midwestern University

Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen in humans. A morphological switch between unicellular budding yeast and multicellular filamentous hyphal growth forms plays a vital role in the virulence of C. albicans, and this transition is regulated in response to a range of environmental cues that are encountered in distinct host niches. Many unique transcription factors contribute to the transcriptional regulatory network that integrates these distinct environmental cues and determines which phenotypic state will be expressed. These hyphal morphogenesis regulators have been extensively investigated, and represent an increasingly important focus of study, due to their central role in controlling a key C. albicans virulence attribute. This review provides a succinct summary of the transcriptional regulatory factors and environmental signals that control hyphal morphogenesis in C. albicans.

Sonia Villa

Masters in Biomedical Science Program,
College of Graduate Studies,
Masters in Biomedical Science Program, College of Graduate Studies

Midwestern University

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Sonia Villa

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Masters in Biomedical Science Program,College of Graduate Studies,Masters in Biomedical Science Program, College of Graduate Studies

Midwestern University

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract

Masters in Biomedical Science Program,
College of Graduate Studies,
Masters in Biomedical Science Program, College of Graduate Studies