Cell Screening Laboratory,
UCD School of Biology and Environmental Science
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Screening the secretion machinery: High throughput imaging approaches to elucidate the secretory pathway.
Seminars in cell & developmental biology Oct, 2009 | Pubmed ID: 19660568
Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth.
EMBO reports Oct, 2009 | Pubmed ID: 19745841
Cationic nanoparticles induce caspase 3-, 7- and 9-mediated cytotoxicity in a human astrocytoma cell line.
Nanotoxicology Dec, 2011 | Pubmed ID: 21142842
Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation.
Molecular & cellular proteomics : MCP Oct, 2011 | Pubmed ID: 21778410
Dual channel rank-based intensity weighting for quantitative co-localization of microscopy images.
BMC bioinformatics Oct, 2011 | Pubmed ID: 22017789
High-speed imaging of Rab family small GTPases reveals rare events in nanoparticle trafficking in living cells.
ACS nano Feb, 2012 | Pubmed ID: 22276691
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway.
Nature cell biology Jun, 2012 | Pubmed ID: 22660414
A method for improved clustering and classification of microscopy images using quantitative co-localization coefficients.
BMC research notes Jun, 2012 | Pubmed ID: 22681635
Chemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia A.
PloS one , 2012 | Pubmed ID: 22973456
Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells.
Journal of nanobiotechnology Sep, 2012 | Pubmed ID: 23006133
Quantitative image analysis approaches for probing Rab GTPase localization and function in mammalian cells.
Biochemical Society transactions Dec, 2012 | Pubmed ID: 23176486
Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc).
PloS one , 2013 | Pubmed ID: 23383136
A real-time impedance based method to assess Rhodococcus equi virulence.
PloS one , 2013 | Pubmed ID: 23555995
Human diseases associated with form and function of the Golgi complex.
International journal of molecular sciences Sep, 2013 | Pubmed ID: 24025425
Time resolved study of cell death mechanisms induced by amine-modified polystyrene nanoparticles.
Nanoscale Nov, 2013 | Pubmed ID: 24108393
High-content screening and analysis of the Golgi complex.
Methods in cell biology , 2013 | Pubmed ID: 24295313
RNAi-mediated inhibition of apoptosis fails to prevent cationic nanoparticle-induced cell death in cultured cells.
Nanomedicine (London, England) Aug, 2014 | Pubmed ID: 24359549
Endoplasmic reticulum stress-activated transcription factor ATF6α requires the disulfide isomerase PDIA5 to modulate chemoresistance.
Molecular and cellular biology May, 2014 | Pubmed ID: 24636989
Actin in action: imaging approaches to study cytoskeleton structure and function.
Cells Nov, 2013 | Pubmed ID: 24709877
HGF induces epithelial-to-mesenchymal transition by modulating the mammalian hippo/MST2 and ISG15 pathways.
Journal of proteome research Jun, 2014 | Pubmed ID: 24766643
The trials and tubule-ations of Rab6 involvement in Golgi-to-ER retrograde transport.
Biochemical Society transactions Oct, 2014 | Pubmed ID: 25233431
Trajectory-based co-localization measures for nanoparticle-cell interaction studies.
Small (Weinheim an der Bergstrasse, Germany) May, 2015 | Pubmed ID: 25504742
Biocompatibility of ferroelectric lithium niobate and the influence of polarization charge on osteoblast proliferation and function.
Journal of biomedical materials research. Part A Aug, 2015 | Pubmed ID: 25504748
Hydroxyapatite and fluorapatite coatings on dental screws: effects of blast coating process and biological response.
Journal of materials science. Materials in medicine Jan, 2015 | Pubmed ID: 25578701
A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways.
Molecular & cellular proteomics : MCP May, 2015 | Pubmed ID: 25759509
High-content analysis for drug delivery and nanoparticle applications.
Drug discovery today Aug, 2015 | Pubmed ID: 25908578
A high-content screening microscopy approach to dissect the role of Rab proteins in Golgi-to-ER retrograde trafficking.
Journal of cell science Jul, 2015 | Pubmed ID: 25999475
High-content analysis of Rab protein function at the ER-Golgi interface.
Bioarchitecture , 2015 | Pubmed ID: 26693811
Implementation of the Rank-Weighted Co-localization (RWC) algorithm in multiple image analysis platforms for quantitative analysis of microscopy images.
Source code for biology and medicine , 2016 | Pubmed ID: 26884809
Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time.
Nature communications Mar, 2016 | Pubmed ID: 26927507
A systematic High-Content Screening microscopy approach reveals key roles for Rab33b, OATL1 and Myo6 in nanoparticle trafficking in HeLa cells.
Scientific reports 07, 2016 | Pubmed ID: 27374232
Genome-Wide siRNA Screening Using Forward Transfection: Identification of Modulators of Membrane Trafficking in Mammalian Cells.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 27581283
Rho GTPases operating at the Golgi complex: Implications for membrane traffic and cancer biology.
Tissue & cell Apr, 2017 | Pubmed ID: 27720426
Systematic functional analysis of the Ras GTPase family unveils a conserved network required for anterograde protein trafficking.
Proteomics 01, 2017 | Pubmed ID: 27957805
Functional characterisation of the YIPF protein family in mammalian cells.
Histochemistry and cell biology Apr, 2017 | Pubmed ID: 27999994
Characterization of carboxylate nanoparticle adhesion with the fungal pathogen Candida albicans.
Nanoscale Oct, 2017 | Pubmed ID: 29019498
Roles for the VCP co-factors Npl4 and Ufd1 in neuronal function in Drosophila melanogaster.
Journal of genetics and genomics = Yi chuan xue bao Oct, 2017 | Pubmed ID: 29037990
Heritable Skeletal Disorders Arising from Defects in Processing and Transport of Type I Procollagen from the ER: Perspectives on Possible Therapeutic Approaches.
Handbook of experimental pharmacology , 2018 | Pubmed ID: 29071510
Bioinspired Star-Shaped Poly(l-lysine) Polypeptides: Efficient Polymeric Nanocarriers for the Delivery of DNA to Mesenchymal Stem Cells.
Molecular pharmaceutics 05, 2018 | Pubmed ID: 29590755
Rapid Growth Cone Uptake and Dynein-Mediated Axonal Retrograde Transport of Negatively Charged Nanoparticles in Neurons Is Dependent on Size and Cell Type.
Small (Weinheim an der Bergstrasse, Germany) 01, 2019 | Pubmed ID: 30565853
Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome.
PloS one , 2019 | Pubmed ID: 30689642
A High-Throughput Automated Confocal Microscopy Platform for Quantitative Phenotyping of Nanoparticle Uptake and Transport in Spheroids.
Small (Weinheim an der Bergstrasse, Germany) 09, 2019 | Pubmed ID: 31334922
Multitasking Rab Proteins in Autophagy and Membrane Trafficking: A Focus on Rab33b.
International journal of molecular sciences Aug, 2019 | Pubmed ID: 31408960
The Challenges and Possibilities of Extracellular Vesicles as Therapeutic Vehicles.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V Nov, 2019 | Pubmed ID: 31419585
Rab35 controls cilium length, function and membrane composition.
EMBO reports 10, 2019 | Pubmed ID: 31432619
NeurodegenERation: The Central Role for ER Contacts in Neuronal Function and Axonopathy, Lessons From Hereditary Spastic Paraplegias and Related Diseases.
Frontiers in neuroscience , 2019 | Pubmed ID: 31680803
Acquisition of fluoroquinolone resistance leads to increased biofilm formation and pathogenicity in Campylobacter jejuni.
Scientific reports 12, 2019 | Pubmed ID: 31796849
Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells.
Molecular therapy : the journal of the American Society of Gene Therapy 04, 2020 | Pubmed ID: 32059764
SCLpred-EMS: subcellular localization prediction of endomembrane system and secretory pathway proteins by Deep N-to-1 Convolutional Neural Networks.
Bioinformatics (Oxford, England) 06, 2020 | Pubmed ID: 32142105
Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes.
PeerJ , 2020 | Pubmed ID: 32185116
Modification of the Mammalian Endomembrane System in Healthy and Diseased Cells.
International journal of molecular sciences Mar, 2020 | Pubmed ID: 32244909
RNA Interference Screening Identifies Novel Roles for RhoBTB1 and RhoBTB3 in Membrane Trafficking Events in Mammalian Cells.
Cells 04, 2020 | Pubmed ID: 32354068
Emerging roles for Rho GTPases operating at the Golgi complex.
Small GTPases Sep-Nov, 2021 | Pubmed ID: 32881632
Antimicrobial effects of airborne acoustic ultrasound and plasma activated water from cold and thermal plasma systems on biofilms.
Scientific reports 10, 2020 | Pubmed ID: 33057158
A novel high-content screening approach for the elucidation of C. jejuni biofilm composition and integrity.
BMC microbiology 01, 2021 | Pubmed ID: 33397288
Inactivation efficacy of atmospheric air plasma and airborne acoustic ultrasound against bacterial biofilms.
Scientific reports 01, 2021 | Pubmed ID: 33504900
A novel automated image analysis pipeline for quantifying morphological changes to the endoplasmic reticulum in cultured human cells.
BMC bioinformatics Sep, 2021 | Pubmed ID: 34496765
Multiparametric nanoparticle-induced toxicity readouts with single cell resolution in HepG2 multicellular tumour spheroids.
Nanoscale Oct, 2021 | Pubmed ID: 34661590
2D-GolgiTrack-a semi-automated tracking system to quantify morphological changes and dynamics of the Golgi apparatus and Golgi-derived membrane tubules.
Medical & biological engineering & computing Nov, 2021 | Pubmed ID: 34783979
Cell3: A new vision for study of the endomembrane system in mammalian cells.
Bioscience reports Nov, 2021 | Pubmed ID: 34793591
Cell3: a new vision for study of the endomembrane system in mammalian cells.
Bioscience reports Dec, 2021 | Pubmed ID: 34874399
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