Seiya Mizuno

Embryonic stem cells derived from C57BL/6J and C57BL/6N mice.

A novel locus on proximal chromosome 18 associated with agenesis of the corpus callosum in mice.

Effect of different culture conditions on establishment of embryonic stem cells from BALB/cAJ and NZB/BINJ mice.

Retrotransposon-mediated Fgf5(go-Utr) mutant mice with long pelage hair.

Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination.

Truncated Cables1 causes agenesis of the corpus callosum in mice.

Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination.

Simple generation of albino C57BL/6J mice with G291T mutation in the tyrosinase gene by the CRISPR/Cas9 system.

Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation.

Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies.

Generation of CRISPR/Cas9-mediated bicistronic knock-in ins1-cre driver mice.

Germline recombination in a novel Cre transgenic line, Prl3b1-Cre mouse.

Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system.

Forward-genetics analysis of sleep in randomly mutagenized mice.

SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells.

Simple generation of hairless mice for in vivo imaging.

Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis.

A mutation in transcription factor MAFB causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome.

ZMYND10 functions in a chaperone relay during axonemal dynein assembly.

De Novo Mutations Activating Germline TP53 in an Inherited Bone-Marrow-Failure Syndrome.

A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice.

Mice harboring an MCTO mutation exhibit renal failure resembling nephropathy in human patients.

Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche.

Generating Vegfr3 reporter transgenic mouse expressing membrane-tagged Venus for visualization of VEGFR3 expression in vascular and lymphatic endothelial cells.

KOnezumi: a web application for automating gene disruption strategies to generate knockout mice.

The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells.

Generation of bicistronic reporter knockin mice for visualizing germ layers.

Lysophosphatidic acid-induced YAP/TAZ activation promotes developmental angiogenesis by repressing Notch ligand Dll4.

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation.

Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition.

Non-invasive in vivo imaging of UCP1 expression in live mice via near-infrared fluorescent protein iRFP720.

Uncovering the role of MAFB in glucagon production and secretion in pancreatic α-cells using a new α-cell-specific Mafb conditional knockout mouse model.

Clec10a regulates mite-induced dermatitis.

Highly efficient CRISPR-targeting of the murine Hipp11 intergenic region supports inducible human transgene expression.

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.

c-MAF deletion in adult C57BL/6J mice induces cataract formation and abnormal differentiation of lens fiber cells.

Generation of B6-Ddx4 , a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9.

Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.

Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes.

Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need.

Reverse genetics reveals single gene of every candidate on Hybrid sterility, X Chromosome QTL 2 (Hstx2) are dispensable for spermatogenesis.

Optimizing Charge Switching in Membrane Lytic Peptides for Endosomal Release of Biomacromolecules.

Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine DR-mediated Sleep Reduction.

Characterization of a bicistronic knock-in reporter mouse model for investigating the role of CABLES2 in vivo.

Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β.

Activation of CD8 T cells accelerates anti-PD-1 antibody-induced psoriasis-like dermatitis through IL-6.

Mast4 knockout shows the regulation of spermatogonial stem cell self-renewal via the FGF2/ERM pathway.

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization.

Induction of Mutant Allele in Neurons in Late Infancy Increases Sleep Need.

Response to correspondence on "Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation".

Disruption of entire locus leads to embryonic lethality by diminished gene expression and enhanced p53 pathway.

EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice.

Efficient induction of proximity-dependent labelling by biotin feeding in BMAL1-BioID knock-in mice.

Starvation-induced transcription factor CREBH negatively governs body growth by controlling GH signaling.

Differential Involvement of Programmed Cell Death Ligands in Skin Immune Responses.

Adipsin-Dependent Secretion of Hepatocyte Growth Factor Regulates the Adipocyte-Cancer Stem Cell Interaction.

A multistate stem cell dynamics maintains homeostasis in mouse spermatogenesis.

Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility.

DAJIN enables multiplex genotyping to simultaneously validate intended and unintended target genome editing outcomes.

Thrombin cleavage of osteopontin initiates osteopontin's tumor-promoting activity.

Erk5 in Bone Marrow Mesenchymal Stem Cells Regulates Bone Homeostasis by Preventing Osteogenesis in Adulthood.

Inducible Systemic Deletion in Mice Leads to Transient Body Weight Loss upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage.

L17ER4: A cell-permeable attenuated cationic amphiphilic lytic peptide.

Generation of a Gal4-dependent gene recombination and illuminating mouse.

Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells.

Birth of mice from meiotically arrested spermatocytes following biparental meiosis in halved oocytes.

Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue.