Department of Biomedical Physiology and Kinesiology
Professor of Biology at Central Michigan University 2017 – present
Associate Professor of Biology at Central Michigan University 2012 – 2017
Assistant Professor of Biology at Central Michigan University 2006 – 2012
Education
Postdoc., Michigan State University, 2002-2006
Postdoc., the Waksman Institute of Microbiology, 2000-2002
Ph.D., Rutgers, the State University of New Jersey, 2000
M.S., University of Akron, 1993
B.S., University of Akron, 1988
Deconvolution of confocal images of dihydropyridine and ryanodine receptors in developing cardiomyocytes.
Journal of applied physiology (Bethesda, Md. : 1985) Sep, 2004 | Pubmed ID: 15064297
Three-dimensional distribution of cardiac Na+-Ca2+ exchanger and ryanodine receptor during development.
Biophysical journal Oct, 2007 | Pubmed ID: 17557789
Distribution patterns of the Na+-Ca2+ exchanger and caveolin-3 in developing rabbit cardiomyocytes.
Cell calcium Apr, 2009 | Pubmed ID: 19250668
Colocalization of voltage-gated Na+ channels with the Na+/Ca2+ exchanger in rabbit cardiomyocytes during development.
American journal of physiology. Heart and circulatory physiology Jan, 2011 | Pubmed ID: 20971761
Optical mapping of the electrical activity of isolated adult zebrafish hearts: acute effects of temperature.
American journal of physiology. Regulatory, integrative and comparative physiology Jun, 2014 | Pubmed ID: 24671241
Morphological phenotyping of mouse hearts using optical coherence tomography.
Journal of biomedical optics , 2014 | Pubmed ID: 25393967
Construction and use of a zebrafish heart voltage and calcium optical mapping system, with integrated electrocardiogram and programmable electrical stimulation.
American journal of physiology. Regulatory, integrative and comparative physiology May, 2015 | Pubmed ID: 25740339
Ischemia-reperfusion destabilizes rhythmicity in immature atrioventricular pacemakers: A predisposing factor for postoperative arrhythmias in neonate rabbits.
Heart rhythm 12, 2016 | Pubmed ID: 27451283
The Zebrafish Heart as a Model of Mammalian Cardiac Function.
Reviews of physiology, biochemistry and pharmacology , 2016 | Pubmed ID: 27538987
Modeling Atrial Fibrillation using Human Embryonic Stem Cell-Derived Atrial Tissue.
Scientific reports 07, 2017 | Pubmed ID: 28706272
Zebrafish as a model of mammalian cardiac function: Optically mapping the interplay of temperature and rate on voltage and calcium dynamics.
Progress in biophysics and molecular biology 10, 2018 | Pubmed ID: 30017908
ROCK2 promotes ryanodine receptor phosphorylation and arrhythmic calcium release in diabetic cardiomyocytes.
International journal of cardiology Apr, 2019 | Pubmed ID: 30728103
In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants.
Proceedings of the National Academy of Sciences of the United States of America 04, 2019 | Pubmed ID: 30886088
Ibrutinib Displays Atrial-Specific Toxicity in Human Stem Cell-Derived Cardiomyocytes.
Stem cell reports 05, 2019 | Pubmed ID: 31031187
Physiological phenotyping of the adult zebrafish heart.
Marine genomics Feb, 2020 | Pubmed ID: 31451352
Investigating the utility of adult zebrafish ex vivo whole hearts to pharmacologically screen hERG channel activator compounds.
American journal of physiology. Regulatory, integrative and comparative physiology 12, 2019 | Pubmed ID: 31664867
The hERG channel activator, RPR260243, enhances protective current early in the refractory period reducing arrhythmogenicity in zebrafish hearts.
American journal of physiology. Heart and circulatory physiology 08, 2020 | Pubmed ID: 32559136
Variation in RARG increases susceptibility to doxorubicin-induced cardiotoxicity in patient specific induced pluripotent stem cell-derived cardiomyocytes.
Scientific reports 06, 2020 | Pubmed ID: 32587261
Drug screening platform using human induced pluripotent stem cell-derived atrial cardiomyocytes and optical mapping.
Stem cells translational medicine 01, 2021 | Pubmed ID: 32927497
Investigating inherited arrhythmias using hiPSC-derived cardiomyocytes.
Methods (San Diego, Calif.) 07, 2022 | Pubmed ID: 34197925
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados