Sunil R. Lakhani

Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype.

The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?

Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival.

Current and future approach to the pathologist's assessment for targeted therapy in breast cancer.

Pleomorphic lobular carcinoma of the breast: molecular pathology and clinical impact.

Pathology of hereditary breast cancer.

The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriers.

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer.

Application of molecular findings to the diagnosis and management of breast disease: recent advances and challenges.

Molecular classification of breast cancer: is it time to pack up our microscopes?

Phenotype-genotype correlation in familial breast cancer.

Tumor heterogeneity in a follicular carcinoma of thyroid: a study by comparative genomic hybridization.

Molecular aspects of breast cancer metastasis to the brain.

Gene expression profiling of tumour epithelial and stromal compartments during breast cancer progression.

Calcium channel TRPV6 as a potential therapeutic target in estrogen receptor-negative breast cancer.

Expression and function of the protein tyrosine phosphatase receptor J (PTPRJ) in normal mammary epithelial cells and breast tumors.

Expression profiling of archival tumors for long-term health studies.

MicroRNA-182-5p targets a network of genes involved in DNA repair.

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.

In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity.

Signatures of mutational processes in human cancer.

Metastatic progression of breast cancer: insights from 50 years of autopsies.

Is the one-step nucleic acid amplification assay better for intra-operative assessment of breast sentinel nodes?

Multifactorial likelihood assessment of BRCA1 and BRCA2 missense variants confirms that BRCA1:c.122A>G(p.His41Arg) is a pathogenic mutation.

Molecular classification of breast cancer.

Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.

ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype.

Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics.

Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib.

An epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomas.

Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer.

TGFβ isoforms and receptors mRNA expression in breast tumours: prognostic value and clinical implications.

High content screening application for cell-type specific behaviour in heterogeneous primary breast epithelial subpopulations.

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin.

Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group.

Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer.

SASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer.

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.

'Omics Approaches in Breast Cancer Research and Clinical Practice.

Current topics in breast pathology: expert perspectives.

Environmental factors in breast cancer invasion: a mathematical modelling review.

Breast Cancer Brain Metastases: Clonal Evolution in Clinical Context.

A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers.

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.

Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer.

Relationship of the Breast Ductal Carcinoma Immune Microenvironment with Clinicopathological and Genetic Features.

Multidimensional phenotyping of breast cancer cell lines to guide preclinical research.

Association analysis identifies 65 new breast cancer risk loci.

Mixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphology.

Expression of MAGE-A and NY-ESO-1 cancer/testis antigens is enriched in triple-negative invasive breast cancers.

Characterization of a novel breast cancer cell line derived from a metastatic bone lesion of a breast cancer patient.

CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer.

Breast cancer metastasis to gynaecological organs: a clinico-pathological and molecular profiling study.

Phenotypic and molecular dissection of metaplastic breast cancer and the prognostic implications.

Recent advances in breast cancer research impacting clinical diagnostic practice.

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

The circular RNome of primary breast cancer.

Diff-Quik Cytology Smears from Endobronchial Ultrasound Transbronchial Needle Aspiration Lymph Node Specimens as a Source of DNA for Next-Generation Sequencing Instead of Cell Blocks.

Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer.

Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases.

Proteomic Analysis of the Breast Cancer Brain Metastasis Microenvironment.

A Molecular and Morphological Deep-Dive Into Metaplastic Breast Cancers.

LobSig is a multigene predictor of outcome in invasive lobular carcinoma.

Breast Cancer Heterogeneity in Primary and Metastatic Disease.

Non-coding RNAs underlie genetic predisposition to breast cancer.

The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.

Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer.

Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer.

Association of Sperm-Associated Antigen 5 and Treatment Response in Patients With Estrogen Receptor-Positive Breast Cancer.

Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1.

Using whole-genome sequencing data to derive the homologous recombination deficiency scores.

Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1.

Clinicopathologic significance of nuclear HER4 and phospho-YAP(S) in human breast cancers and matching brain metastases.

The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence.

Lobular carcinoma in situ: diagnostic criteria and molecular correlates.

Phenotypic drift in metastatic progression of breast cancer: A case report with histologically heterogeneous lesions that are clonally related.

Invasive lobular carcinoma of the breast: the increasing importance of this special subtype.

An Update on the Molecular Pathology of Metaplastic Breast Cancer.

Spatial profiling technologies and applications for brain cancers.

Tumor Signature Analysis Implicates Hereditary Cancer Genes in Endometrial Cancer Development.

The Genomic Landscape of Lobular Breast Cancer.

Characterization of Immune Cell Subsets of Tumor Infiltrating Lymphocytes in Brain Metastases.

Altered Calcium Influx Pathways in Cancer-Associated Fibroblasts.

Correction: McCart Reed et al. The Genomic Landscape of Lobular Breast Cancer. 2021, , 1950.

Elevating CDCA3 Levels Enhances Tyrosine Kinase Inhibitor Sensitivity in TKI-Resistant EGFR Mutant Non-Small-Cell Lung Cancer.

Blood-Derived Extracellular Vesicle-Associated miR-3182 Detects Non-Small Cell Lung Cancer Patients.

Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content.

Landscape of Epidermal Growth Factor Receptor Heterodimers in Brain Metastases.

Emerging Biomarkers for Diagnosis, Prevention and Treatment of Brain Metastases-From Biology to Clinical Utility.

N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease.

Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer.

The increasing importance of pathology in modern clinical trial conduct: OlympiA as a case in point.