School of Medicine,
Institute for Mental and Physical Health and Clinical Translation,
Institute for Mental and Physical Health and Clinical Translation, School of Medicine
Sarah Shigdar has not added Biography.
If you are Sarah Shigdar and would like to personalize this page please email our Author Liaison for assistance.
Functional interaction between mutations in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia.
British journal of haematology Aug, 2008 | Pubmed ID: 18513286
Cytochemical characterisation of the leucocytes and thrombocytes from Murray cod (Maccullochella peelii peelii, Mitchell).
Fish & shellfish immunology May, 2009 | Pubmed ID: 19332132
RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule.
Cancer science May, 2011 | Pubmed ID: 21281402
Clinical applications of aptamers and nucleic acid therapeutics in haematological malignancies.
British journal of haematology Oct, 2011 | Pubmed ID: 21810089
Cancer stem cell targeting: the next generation of cancer therapy and molecular imaging.
Therapeutic delivery Feb, 2012 | Pubmed ID: 22834199
Enhanced antitumor efficacy and reduced systemic toxicity of sulfatide-containing nanoliposomal doxorubicin in a xenograft model of colorectal cancer.
PloS one , 2012 | Pubmed ID: 23145140
RNA aptamers targeting cancer stem cell marker CD133.
Cancer letters Mar, 2013 | Pubmed ID: 23196060
The use of sensitive chemical antibodies for diagnosis: detection of low levels of EpCAM in breast cancer.
PloS one , 2013 | Pubmed ID: 23460885
Inflammation and cancer stem cells.
Cancer letters Apr, 2014 | Pubmed ID: 23941828
Aptamers as theranostic agents: modifications, serum stability and functionalisation.
Sensors (Basel, Switzerland) Oct, 2013 | Pubmed ID: 24152925
Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivo.
International journal of nanomedicine , 2013 | Pubmed ID: 24204140
Cancer stem cells: A contentious hypothesis now moving forward.
Cancer letters Mar, 2014 | Pubmed ID: 24333726
Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells.
International journal of nanomedicine , 2014 | Pubmed ID: 24591829
Improved efficacy and reduced toxicity of doxorubicin encapsulated in sulfatide-containing nanoliposome in a glioma model.
PloS one , 2014 | Pubmed ID: 25072631
Nucleic acid aptamer-guided cancer therapeutics and diagnostics: the next generation of cancer medicine.
Theranostics , 2015 | Pubmed ID: 25553096
Fabrication of high specificity hollow mesoporous silica nanoparticles assisted by Eudragit for targeted drug delivery.
Journal of colloid and interface science May, 2015 | Pubmed ID: 25617610
Superior Performance of Aptamer in Tumor Penetration over Antibody: Implication of Aptamer-Based Theranostics in Solid Tumors.
Theranostics , 2015 | Pubmed ID: 26199647
Overcoming acquired drug resistance in colorectal cancer cells by targeted delivery of 5-FU with EGF grafted hollow mesoporous silica nanoparticles.
Nanoscale Sep, 2015 | Pubmed ID: 26242620
Cancer stem cell targeted therapy: progress amid controversies.
Oncotarget Dec, 2015 | Pubmed ID: 26496035
Application of Aptamers in Histopathology.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 26552827
EpCAM Aptamer-mediated Survivin Silencing Sensitized Cancer Stem Cells to Doxorubicin in a Breast Cancer Model.
Theranostics , 2015 | Pubmed ID: 26681989
The Application of Aptamers for Immunohistochemistry.
Nucleic acid therapeutics 06, 2016 | Pubmed ID: 26862683
Challenges and opportunities for siRNA-based cancer treatment.
Cancer letters 02, 2017 | Pubmed ID: 27045474
Tailored Mesoporous Silica Nanoparticles for Controlled Drug Delivery: Platform Fabrication, Targeted Delivery, and Computational Design and Analysis.
Mini reviews in medicinal chemistry , 2018 | Pubmed ID: 27145854
Truncation and Mutation of a Transferrin Receptor Aptamer Enhances Binding Affinity.
Nucleic acid therapeutics 12, 2016 | Pubmed ID: 27500826
Development of a Bifunctional Aptamer Targeting the Transferrin Receptor and Epithelial Cell Adhesion Molecule (EpCAM) for the Treatment of Brain Cancer Metastases.
ACS chemical neuroscience 04, 2017 | Pubmed ID: 28010059
What potential do aptamers hold in therapeutic delivery?
Therapeutic delivery 02, 2017 | Pubmed ID: 28088878
Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells.
Scientific reports 07, 2017 | Pubmed ID: 28724889
Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery.
Theranostics , 2017 | Pubmed ID: 29158811
Development of Cell-Specific Aptamers: Recent Advances and Insight into the Selection Procedures.
Molecules (Basel, Switzerland) Nov, 2017 | Pubmed ID: 29186905
Aptamers and Glioblastoma: Their Potential Use for Imaging and Therapeutic Applications.
International journal of molecular sciences Nov, 2017 | Pubmed ID: 29189740
Aptamers as potential therapeutic agents for ovarian cancer.
Biochimie Feb, 2018 | Pubmed ID: 29224849
EpCAM Immunotherapy versus Specific Targeted Delivery of Drugs.
Cancers Jan, 2018 | Pubmed ID: 29329202
Radiolabelled Aptamers for Theranostic Treatment of Cancer.
Pharmaceuticals (Basel, Switzerland) Dec, 2018 | Pubmed ID: 30586898
Aptamer-Based Diagnostics and Therapeutics.
Pharmaceuticals (Basel, Switzerland) Jan, 2019 | Pubmed ID: 30609700
Anything You Can Do, I Can Do Better: Can Aptamers Replace Antibodies in Clinical Diagnostic Applications?
Molecules (Basel, Switzerland) Nov, 2019 | Pubmed ID: 31801185
Bifunctional Aptamer-Doxorubicin Conjugate Crosses the Blood-Brain Barrier and Selectively Delivers Its Payload to EpCAM-Positive Tumor Cells.
Nucleic acid therapeutics 04, 2020 | Pubmed ID: 32027209
Antibodies, Nanobodies, or Aptamers-Which Is Best for Deciphering the Proteomes of Non-Model Species?
International journal of molecular sciences Apr, 2020 | Pubmed ID: 32260091
The control of epidermal growth factor grafted on mesoporous silica nanoparticles for targeted delivery.
Journal of materials chemistry. B Aug, 2015 | Pubmed ID: 32262664
Mathematical approaches in estimating aptamer-target binding affinity.
Analytical biochemistry 07, 2020 | Pubmed ID: 32315616
Strategies to bioengineer aptamer-driven nanovehicles as exceptional molecular tools for targeted therapeutics: A review.
Journal of controlled release : official journal of the Controlled Release Society 07, 2020 | Pubmed ID: 32380206
Non-Invasive Delivery of Therapeutics into the Brain: The Potential of Aptamers for Targeted Delivery.
Biomedicines May, 2020 | Pubmed ID: 32422973
Author Correction: Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells.
Scientific reports Dec, 2020 | Pubmed ID: 33311517
Novel Detection of Nasty Bugs, Prevention Is Better than Cure.
International journal of molecular sciences Dec, 2020 | Pubmed ID: 33375709
Aptamers: Cutting edge of cancer therapies.
Molecular therapy : the journal of the American Society of Gene Therapy 08, 2021 | Pubmed ID: 34146729
Diagnostics and Therapeutics in Targeting HER2 Breast Cancer: A Novel Approach.
International journal of molecular sciences Jun, 2021 | Pubmed ID: 34200484
Future of PD-1/PD-L1 axis modulation for the treatment of triple-negative breast cancer.
Pharmacological research 01, 2022 | Pubmed ID: 34861397
Profiling Cancer Cells by Cell-SELEX: Use of Aptamers for Discovery of Actionable Biomarkers and Therapeutic Applications Thereof.
Pharmaceutics Dec, 2021 | Pubmed ID: 35056924
Triple-negative breast cancer brain metastasis: An update on druggable targets, current clinical trials, and future treatment options.
Drug discovery today 05, 2022 | Pubmed ID: 35101641
Modelling of mass transport and distribution of aptamer in blood-brain barrier for tumour therapy and cancer treatment.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V Apr, 2022 | Pubmed ID: 35283304
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados