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Department of Applied Stem Cell Technologies,
TechMed Centre Enschede,
Department of Applied Stem Cell Technologies, TechMed Centre Enschede
Kerensa Broersen has not added Biography.
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A comparative analysis of the aggregation behavior of amyloid-β peptide variants.
FEBS letters Nov, 2012 | Pubmed ID: 23103738
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio.
The EMBO journal Oct, 2010 | Pubmed ID: 20818335
Structural basis for increased toxicity of pathological aβ42:aβ40 ratios in Alzheimer disease.
The Journal of biological chemistry Feb, 2012 | Pubmed ID: 22157754
The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.
The EMBO journal May, 2012 | Pubmed ID: 22505025
Molecular plasticity regulates oligomerization and cytotoxicity of the multipeptide-length amyloid-β peptide pool.
The Journal of biological chemistry Oct, 2012 | Pubmed ID: 22992745
New mimetic peptides inhibitors of Αβ aggregation. Molecular guidance for rational drug design.
European journal of medicinal chemistry May, 2015 | Pubmed ID: 25805447
Two distinct β-sheet structures in Italian-mutant amyloid-beta fibrils: a potential link to different clinical phenotypes.
Cellular and molecular life sciences : CMLS Dec, 2015 | Pubmed ID: 26190022
Could ecosystem management provide a new framework for Alzheimer's disease?
Alzheimer's & dementia : the journal of the Alzheimer's Association Jan, 2016 | Pubmed ID: 26341147
Characterization of insulin-degrading enzyme-mediated cleavage of Aβ in distinct aggregation states.
Biochimica et biophysica acta Jun, 2016 | Pubmed ID: 26968463
Optimized Triton X-114 assisted lipopolysaccharide (LPS) removal method reveals the immunomodulatory effect of food proteins.
PloS one , 2017 | Pubmed ID: 28355240
Structural and Aggregation Properties of Alpha-Synuclein Linked to Phospholipase A2 Action.
Protein and peptide letters , 2018 | Pubmed ID: 29577851
Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β monomer.
Bioorganic chemistry Dec, 2018 | Pubmed ID: 30144634
Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound.
Future medicinal chemistry Feb, 2019 | Pubmed ID: 30801198
Apolipoprotein E associated with reconstituted high-density lipoprotein-like particles is protected from aggregation.
FEBS letters Jun, 2019 | Pubmed ID: 31058310
Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD , 2019 | Pubmed ID: 31744008
Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V.
Protein engineering, design & selection : PEDS Dec, 2019 | Pubmed ID: 32399571
Milk Processing Affects Structure, Bioavailability and Immunogenicity of β-lactoglobulin.
Foods (Basel, Switzerland) Jul, 2020 | Pubmed ID: 32635246
Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation.
Chemico-biological interactions Jan, 2021 | Pubmed ID: 33098838
Cross-seeding of alpha-synuclein aggregation by amyloid fibrils of food proteins.
The Journal of biological chemistry , 2021 | Pubmed ID: 33539920
A Review of Oxidative Stress Products and Related Genes in Early Alzheimer's Disease.
Journal of Alzheimer's disease : JAD , 2021 | Pubmed ID: 34420962
Engineering Organoids for Modeling of Phenylketonuria.
Frontiers in molecular neuroscience , 2021 | Pubmed ID: 35082602
Use of standard U-bottom and V-bottom well plates to generate neuroepithelial embryoid bodies.
PloS one , 2022 | Pubmed ID: 35536781
Alzheimer's Disease: Treatment Strategies and Their Limitations.
International journal of molecular sciences Nov, 2022 | Pubmed ID: 36430432
University of Twente
Lena Sophie Koch1,
David Choy Buentello2,3,
Kerensa Broersen1
1Department of Applied Stem Cell Technologies, TechMed Centre Enschede, University of Twente,
2Centro de Biotecnología-FEMSA, Tecnologico de Monterrey,
3Department of Genetics, Harvard Medical School
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