Lester & Sue Smith Breast Center,
Department of Medicine
Wen Bu has not added Biography.
If you are Wen Bu and would like to personalize this page please email our Author Liaison for assistance.
Keratin 6 is not essential for mammary gland development.
Breast cancer research : BCR , 2006 | Pubmed ID: 16790075
Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors.
Neoplasia (New York, N.Y.) Jul, 2008 | Pubmed ID: 18592025
Lentivirus vectors for stably introducing genes into mammary epithelial cells in vivo.
Journal of mammary gland biology and neoplasia Dec, 2009 | Pubmed ID: 19936990
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2010 | Pubmed ID: 20133707
Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer.
Oncogene Oct, 2011 | Pubmed ID: 21532625
EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis.
Molecular cell Dec, 2012 | Pubmed ID: 23123196
A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells.
Cell research Mar, 2013 | Pubmed ID: 23266888
Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells.
The Journal of biological chemistry Jul, 2013 | Pubmed ID: 23678002
Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells.
The Journal of pathology Jan, 2014 | Pubmed ID: 24122835
Mammary cells with active Wnt signaling resist ErbB2-induced tumorigenesis.
PloS one , 2013 | Pubmed ID: 24265712
Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer.
Stem cells translational medicine Jul, 2014 | Pubmed ID: 24797826
STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer.
Stem cells (Dayton, Ohio) Oct, 2014 | Pubmed ID: 24891218
Krt6a-positive mammary epithelial progenitors are not at increased vulnerability to tumorigenesis initiated by ErbB2.
PloS one , 2015 | Pubmed ID: 25635772
Luminal epithelial cells within the mammary gland can produce basal cells upon oncogenic stress.
Oncogene Mar, 2016 | Pubmed ID: 26096929
Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation.
Cell reports Jul, 2015 | Pubmed ID: 26166574
Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype.
International journal of biological sciences , 2016 | Pubmed ID: 27019623
Breast tumor cell-specific knockout of inhibits cancer cell plasticity, dissemination, and lung metastasis in mice.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2017 | Pubmed ID: 29073077
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
The Journal of clinical investigation 04, 2018 | Pubmed ID: 29480818
Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes.
Cancer research 01, 2019 | Pubmed ID: 30401712
Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms.
Nature cell biology 09, 2019 | Pubmed ID: 31451770
Intraductal Injection of Lentivirus Vectors for Stably Introducing Genes into Rat Mammary Epithelial Cells in Vivo.
Journal of mammary gland biology and neoplasia Dec, 2020 | Pubmed ID: 33165800
Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer.
Cancer prevention research (Philadelphia, Pa.) Jan, 2022 | Pubmed ID: 34667127
High-throughput profiling of histone post-translational modifications and chromatin modifying proteins by reverse phase protein array.
Journal of proteomics Jun, 2022 | Pubmed ID: 35489683
Short-term PI3K Inhibition Prevents Breast Cancer in Preclinical Models.
Cancer prevention research (Philadelphia, Pa.) Feb, 2023 | Pubmed ID: 36343340
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados