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Ben Towne Center for Childhood Cancer Research
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Immunotherapy for brain tumors: understanding early successes and limitations.
Expert review of neurotherapeutics Mar, 2018 | Pubmed ID: 29322843
Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: implications for development of immunotherapy.
Neuro-oncology Jan, 2019 | Pubmed ID: 30169876
Diffuse Intrinsic Pontine Glioma: From Diagnosis to Next-Generation Clinical Trials.
Current treatment options in neurology Jul, 2019 | Pubmed ID: 31290035
EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma.
Oncotarget Dec, 2019 | Pubmed ID: 31903167
Children with DIPG and high-grade glioma treated with temozolomide, irinotecan, and bevacizumab: the Seattle Children's Hospital experience.
Journal of neuro-oncology Jul, 2020 | Pubmed ID: 32556862
Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models.
Neuro-oncology Mar, 2021 | Pubmed ID: 33130903
Considerations when treating high-grade pediatric glioma patients with immunotherapy.
Expert review of neurotherapeutics Feb, 2021 | Pubmed ID: 33225764
MRI-based radiomics for prognosis of pediatric diffuse intrinsic pontine glioma: an international study.
Neuro-oncology advances , 2021 | Pubmed ID: 33977272
Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis.
Nature medicine Sep, 2021 | Pubmed ID: 34253928
Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies.
Oncogene Jan, 2022 | Pubmed ID: 34759345
Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma.
Neuro-oncology advances , 2021 | Pubmed ID: 34988452
Two cases of pineal anlage tumor with molecular analysis.
Pediatric blood & cancer Apr, 2022 | Pubmed ID: 35129878
Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma.
Neuro-oncology Aug, 2022 | Pubmed ID: 35137228
Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas.
Neuro-oncology Sep, 2022 | Pubmed ID: 35157764
The intrinsic and microenvironmental features of diffuse midline glioma: Implications for the development of effective immunotherapeutic treatment strategies.
Neuro-oncology Sep, 2022 | Pubmed ID: 35481923
Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety.
Cancer discovery Jan, 2023 | Pubmed ID: 36259971
Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy.
Neuro-oncology advances , 2022 | Pubmed ID: 36382108
Locoregional CAR T cells for children with CNS tumors: Clinical procedure and catheter safety.
Neoplasia (New York, N.Y.) Feb, 2023 | Pubmed ID: 36599192
Functional genomic analysis of adult and pediatric brain tumor isolates.
bioRxiv : the preprint server for biology Jan, 2023 | Pubmed ID: 36711964
Seattle Children’s Research Institute
University of Washington
Kyra Harvey1,
Peter J. Madsen2,3,
Tiffany Smith2,
Crystal Griffin1,2,
Luke Patterson1,2,
Nicholas A. Vitanza4,5,
Phillip B. Storm2,3,
Adam C. Resnick2,3,
Jessica B. Foster1,2
1Division of Oncology, Children’s Hospital of Philadelphia,
2Center for Data Driven Discovery in Biomedicine, Children’s Hospital of Philadelphia,
3Division of Neurosurgery, Children’s Hospital of Philadelphia,
4Ben Towne Center for Childhood Cancer Research, Seattle Children’s Research Institute,
5Department of Pediatrics, Seattle Children’s Hospital, University of Washington
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