Center for Data Driven Discovery in Biomedicine,
Division of Neurosurgery
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Drivers of In-Hospital Costs Following Endoscopic Transphenoidal Pituitary Surgery.
The Laryngoscope Apr, 2021 | Pubmed ID: 32830866
Systemic BCNU enhances the efficacy of local delivery of a topoisomerase I inhibitor against malignant glioma.
Cancer chemotherapy and pharmacology Oct, 2004 | Pubmed ID: 15197484
Use of allogeneic skin graft for the closure of large meningomyeloceles: technical case report.
Neurosurgery Apr, 2006 | Pubmed ID: 16575293
Surgical clipping of a PICA aneurysm in a 6-month-old child.
Pediatric neurosurgery , 2006 | Pubmed ID: 17047426
Successful microsurgical extraction of a migrated coil in a pediatric patient after failed endovascular closure of a Blalock-Taussig shunt. Case report.
Journal of neurosurgery Feb, 2007 | Pubmed ID: 17330541
Cervical chordoma in a patient with tuberous sclerosis presenting with shoulder pain.
Pediatric neurosurgery , 2007 | Pubmed ID: 17337935
Comparison of novel computer detectors and human performance for spike detection in intracranial EEG.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Aug, 2007 | Pubmed ID: 17544322
Dislocation of the mandible into the middle cranial fossa. Case report.
Journal of neurosurgery Jul, 2007 | Pubmed ID: 17644926
Surgical management of pediatric brain tumors.
Expert review of anticancer therapy Dec, 2007 | Pubmed ID: 18076320
Cranial fetus in fetu. Case illustration.
Journal of neurosurgery. Pediatrics Feb, 2008 | Pubmed ID: 18352794
Multiple ruptured cerebral aneurysms in a child with Takayasu arteritis.
Journal of neurosurgery. Pediatrics Jan, 2008 | Pubmed ID: 18352809
Lumbar puncture and surgical intervention in a child with undiagnosed fibrodysplasia ossificans progressiva.
Journal of neurosurgery. Pediatrics Jan, 2008 | Pubmed ID: 18352811
Treatment of osteoblastoma at C7: a multidisciplinary approach. A case report and review of the literature.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society Jul, 2009 | Pubmed ID: 18839223
Endovascular and surgical treatment of ruptured cerebral aneurysms in pediatric patients.
Neurosurgery Nov, 2008 | Pubmed ID: 19005375
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene.
Brain pathology (Zurich, Switzerland) Jul, 2009 | Pubmed ID: 19016743
Treatment of pediatric atlantoaxial instability with traditional and modified Goel-Harms fusion constructs.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society Jun, 2009 | Pubmed ID: 19357876
Interictal EEG spikes identify the region of electrographic seizure onset in some, but not all, pediatric epilepsy patients.
Epilepsia Apr, 2010 | Pubmed ID: 19780794
Predictors of outcome in childhood intracerebral hemorrhage: a prospective consecutive cohort study.
Stroke; a journal of cerebral circulation Feb, 2010 | Pubmed ID: 20019325
Surgical treatment of a clival-C2 atypical teratoid/rhabdoid tumor.
Journal of neurosurgery. Pediatrics Jan, 2010 | Pubmed ID: 20043739
Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas.
Neuro-oncology Jul, 2010 | Pubmed ID: 20156809
ABC/XYZ estimates intracerebral hemorrhage volume as a percent of total brain volume in children.
Stroke; a journal of cerebral circulation Apr, 2010 | Pubmed ID: 20181678
The genetic landscape of the childhood cancer medulloblastoma.
Science (New York, N.Y.) Jan, 2011 | Pubmed ID: 21163964
Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2011 | Pubmed ID: 21220345
Use of the vascularized free fibula graft with an arteriovenous loop for fusion of cervical and thoracic spinal defects in previously irradiated pediatric patients.
Plastic and reconstructive surgery May, 2011 | Pubmed ID: 21228740
Fluoroscopically guided, transoral, closed reduction, and halo vest immobilization for an atypical C-1 fracture.
Journal of neurosurgery. Pediatrics Apr, 2011 | Pubmed ID: 21456909
Treatment of a malignant peripheral nerve sheath tumor and its complications through a multidisciplinary approach.
Journal of neurosurgery. Pediatrics May, 2011 | Pubmed ID: 21529197
Perioperative seizure incidence and risk factors in 223 pediatric brain tumor patients without prior seizures.
Journal of neurosurgery. Pediatrics Jun, 2011 | Pubmed ID: 21631197
Cerebral salt wasting syndrome in post-operative pediatric brain tumor patients.
Neurocritical care Dec, 2012 | Pubmed ID: 21822747
Surgical treatment of brain tumors in infants younger than six months of age and review of the literature.
World neurosurgery Jul, 2012 | Pubmed ID: 22120270
Follow-up imaging to detect recurrence of surgically treated pediatric arteriovenous malformations.
Journal of neurosurgery. Pediatrics May, 2012 | Pubmed ID: 22546027
Spinal cord ependymomas and myxopapillary ependymomas in the first 2 decades of life: a clinicopathological and immunohistochemical characterization of 19 cases.
Journal of neurosurgery. Pediatrics Jun, 2012 | Pubmed ID: 22656257
Cranial irradiation increases risk of stroke in pediatric brain tumor survivors.
Stroke Nov, 2012 | Pubmed ID: 22968468
Intrarater and interrater reliability of the pediatric arteriovenous malformation compactness score in children.
Journal of neurosurgery. Pediatrics May, 2013 | Pubmed ID: 23495808
Monobloc minus Le Fort II for single-stage treatment of the Apert phenotype.
The Journal of craniofacial surgery Mar, 2013 | Pubmed ID: 23524752
Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2013 | Pubmed ID: 23533272
Monobloc minus Le Fort II for single-stage treatment of the Apert phenotype.
The Journal of craniofacial surgery Jul, 2013 | Pubmed ID: 24015416
Prenatal diagnosis of hemimegalencephaly.
World neurosurgery , 2014 | Pubmed ID: 24056222
Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.
Nature genetics Feb, 2014 | Pubmed ID: 24413733
Risk factors associated with infections and need for permanent cerebrospinal fluid diversion in pediatric intensive care patients with externalized ventricular drains.
Neurocritical care Oct, 2014 | Pubmed ID: 24522759
Leaving tissue associated with infrequent intracranial EEG seizure onsets is compatible with post-operative seizure freedom.
Journal of pediatric epilepsy , 2012 | Pubmed ID: 24563805
Greater fluctuations in serum sodium levels are associated with increased mortality in children with externalized ventriculostomy drains in a PICU.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies Nov, 2014 | Pubmed ID: 25137551
Endoscopic approaches to brainstem cavernous malformations: Case series and review of the literature.
Surgical neurology international , 2015 | Pubmed ID: 25984383
Pediatric nasoseptal flap reconstruction for suprasellar approaches.
The Laryngoscope Nov, 2015 | Pubmed ID: 26016422
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.
Nature genetics Mar, 2016 | Pubmed ID: 26829751
Management of Giant Cervical Teratoma with Intracranial Extension Diagnosed in Utero.
Journal of neurological surgery reports Jul, 2016 | Pubmed ID: 27468407
External validity of the chiari severity index and outcomes among pediatric chiari I patients treated with intra- or extra-Dural decompression.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Feb, 2017 | Pubmed ID: 27921214
Correlations of atrial diameter and frontooccipital horn ratio with ventricle size in fetal ventriculomegaly.
Journal of neurosurgery. Pediatrics Mar, 2017 | Pubmed ID: 28059680
Evaluation of Optical Coherence Tomography to Detect Elevated Intracranial Pressure in Children.
JAMA ophthalmology Apr, 2017 | Pubmed ID: 28241164
Comprehensive Analysis of Hypermutation in Human Cancer.
Cell Nov, 2017 | Pubmed ID: 29056344
Overcoming resistance to single-agent therapy for oncogenic gene fusions combinatorial targeting of MAPK and PI3K/mTOR signaling pathways.
Oncotarget Oct, 2017 | Pubmed ID: 29156677
Use of Fetal Magnetic Resonance Image Analysis and Machine Learning to Predict the Need for Postnatal Cerebrospinal Fluid Diversion in Fetal Ventriculomegaly.
JAMA pediatrics Feb, 2018 | Pubmed ID: 29255892
The effect and evolution of patient selection on outcomes in endoscopic third ventriculostomy for hydrocephalus: A large-scale review of the literature.
Journal of the neurological sciences Feb, 2018 | Pubmed ID: 29406903
Novel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation.
Acta neuropathologica Jul, 2018 | Pubmed ID: 29767381
De Novo Mutation in Genes Regulating Neural Stem Cell Fate in Human Congenital Hydrocephalus.
Neuron 07, 2018 | Pubmed ID: 29983323
Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response.
Human gene therapy Feb, 2019 | Pubmed ID: 30024272
Intraoperative intracranial pressure monitoring in the pediatric craniosynostosis population.
Journal of neurosurgery. Pediatrics Nov, 2018 | Pubmed ID: 30074450
Clinicopathologic features of anaplastic myxopapillary ependymomas.
Brain pathology (Zurich, Switzerland) Jan, 2019 | Pubmed ID: 30417460
Lack of Sphenoid Pneumatization Does Not Affect Endoscopic Endonasal Pediatric Skull Base Surgery Outcomes.
The Laryngoscope Apr, 2019 | Pubmed ID: 30520033
Separation of Craniopagus Twins by a Multidisciplinary Team.
The New England journal of medicine Jan, 2019 | Pubmed ID: 30673542
Endoscopic third ventriculostomy prior to resection of posterior fossa tumors in children.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery May, 2019 | Pubmed ID: 30895380
Transcriptome signatures associated with meningioma progression.
Acta neuropathologica communications Apr, 2019 | Pubmed ID: 31039818
The impact of expanded endonasal skull base surgery on midfacial growth in pediatric patients.
The Laryngoscope Feb, 2020 | Pubmed ID: 31070247
Endoscopic endonasal resection versus open surgery for pediatric craniopharyngioma: comparison of outcomes and complications.
Journal of neurosurgery. Pediatrics Jun, 2019 | Pubmed ID: 31174192
Development and Clinical Validation of a Large Fusion Gene Panel for Pediatric Cancers.
The Journal of molecular diagnostics : JMD Sep, 2019 | Pubmed ID: 31255796
Reduction of ventriculostomy-associated CSF infection with antibiotic-impregnated catheters in pediatric patients: a single-institution study.
Neurosurgical focus Aug, 2019 | Pubmed ID: 31370025
Immunotherapy for pediatric brain tumors: past and present.
Neuro-oncology Oct, 2019 | Pubmed ID: 31504801
Pediatric high-grade glioma resources from the Children's Brain Tumor Tissue Consortium.
Neuro-oncology Jan, 2020 | Pubmed ID: 31613963
Genomic Analysis of Dysembryoplastic Neuroepithelial Tumor Spectrum Reveals a Diversity of Molecular Alterations Dysregulating the MAPK and PI3K/mTOR Pathways.
Journal of neuropathology and experimental neurology Dec, 2019 | Pubmed ID: 31617914
Laparoscopy assisted ventriculoperitoneal shunt placement in children.
Journal of pediatric surgery Feb, 2020 | Pubmed ID: 31718873
Low-grade astrocytoma in the setting of a developmental venous anomaly.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Jun, 2020 | Pubmed ID: 31776715
Perioperative near-infrared spectroscopy cerebral oxygen saturation in symptomatic pediatric hydrocephalus patients at risk for intracranial hypertension.
Journal of neurosurgery. Pediatrics Nov, 2019 | Pubmed ID: 31783356
A Retrospective Study of Neurological Complications in Pediatric Patients With Moyamoya Disease Undergoing General Anesthesia.
Anesthesia and analgesia Feb, 2021 | Pubmed ID: 32149758
Decadron, Diamox, and Zantac: A Novel Combination for Ventricular Shunt Failure in Pediatric Neurosurgical Patients.
Pediatric emergency care Dec, 2021 | Pubmed ID: 32195984
Magnetic resonance-guided stereotactic laser ablation therapy for the treatment of pediatric brain tumors: a multiinstitutional retrospective study.
Journal of neurosurgery. Pediatrics Mar, 2020 | Pubmed ID: 32217793
Intracranial Pressure and Brain Tissue Oxygen Neuromonitoring in Pediatric Cerebral Malaria.
World neurosurgery Sep, 2020 | Pubmed ID: 32526359
Prophylactic Decompression for Cervical Stenosis in Jeune Syndrome: Report From a Single Institution.
Spine Jul, 2020 | Pubmed ID: 32539291
A germline pathogenic variant identified in a pediatric high-grade glioma.
Cold Spring Harbor molecular case studies Aug, 2020 | Pubmed ID: 32554798
Head of bed elevation in pediatric patients with severe traumatic brain injury.
Journal of neurosurgery. Pediatrics Jul, 2020 | Pubmed ID: 32679558
Predicting pediatric optic pathway glioma progression using advanced magnetic resonance image analysis and machine learning.
Neuro-oncology advances , 2020 | Pubmed ID: 32885166
A transcriptome-based classifier to determine molecular subtypes in medulloblastoma.
PLoS computational biology Oct, 2020 | Pubmed ID: 33119584
Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer.
Cell Dec, 2020 | Pubmed ID: 33242424
annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions.
BMC bioinformatics Dec, 2020 | Pubmed ID: 33317447
Genomic characterization of a PPP1CB-ALK fusion with fusion gene amplification in a congenital glioblastoma.
Cancer genetics Apr, 2021 | Pubmed ID: 33341678
BRAF fusions in pediatric histiocytic neoplasms define distinct therapeutic responsiveness to RAF paradox breakers.
Pediatric blood & cancer Jun, 2021 | Pubmed ID: 33565241
Hemicraniectomy and externalized ventricular drain placement in a pediatric patient with myelin oligodendrocyte glycoprotein-associated tumefactive demyelinating disease.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Jan, 2022 | Pubmed ID: 33796928
Development of best practices in the utilization and implementation of pediatric cervical spine traction: a modified Delphi study.
Journal of neurosurgery. Pediatrics Apr, 2021 | Pubmed ID: 33799292
Optical Detection of Intracranial Pressure and Perfusion Changes in Neonates With Hydrocephalus.
The Journal of pediatrics Sep, 2021 | Pubmed ID: 34004191
NTRK Fusions Identified in Pediatric Tumors: The Frequency, Fusion Partners, and Clinical Outcome.
JCO precision oncology , 2021 | Pubmed ID: 34036219
DIAPH1 Variants in Non-East Asian Patients With Sporadic Moyamoya Disease.
JAMA neurology Aug, 2021 | Pubmed ID: 34125151
Acute neurological injury in pediatric patients with single-ventricle congenital heart disease.
Journal of neurosurgery. Pediatrics Jul, 2021 | Pubmed ID: 34243155
Spring-mediated cranioplasty versus endoscopic strip craniectomy for sagittal craniosynostosis.
Journal of neurosurgery. Pediatrics Jul, 2021 | Pubmed ID: 34298510
Targeted gene expression profiling of inverted papilloma and squamous cell carcinoma.
International forum of allergy & rhinology Feb, 2022 | Pubmed ID: 34510780
Trajectory of Long-Term Outcome in Severe Pediatric Diffuse Axonal Injury: An Exploratory Study.
Frontiers in neurology , 2021 | Pubmed ID: 34594294
Arterial spin labeling as an ancillary assessment to postoperative conventional angiogram in pediatric moyamoya disease.
Journal of neurosurgery. Pediatrics Jan, 2022 | Pubmed ID: 34598159
Urgent Neurosurgical Interventions in the COVID-19-Positive Pediatric Population.
World neurosurgery Feb, 2022 | Pubmed ID: 34718196
Comparison of high-flow CSF leak closure with nasoseptal flap following endoscopic endonasal approach in adult and pediatric populations.
International forum of allergy & rhinology Mar, 2022 | Pubmed ID: 34719119
Neurotrophic tyrosine receptor kinase fusion in pediatric central nervous system tumors.
Cancer genetics Apr, 2022 | Pubmed ID: 35108662
Pediatric Pituitary Surgery.
Otolaryngologic clinics of North America Apr, 2022 | Pubmed ID: 35256170
Surgical management and outcomes of intracranial metastatic Wilms' tumor in the pediatric population: a case series.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Jun, 2022 | Pubmed ID: 35377009
Outcomes of endoscopic endonasal resection of pediatric craniopharyngiomas.
International forum of allergy & rhinology Dec, 2022 | Pubmed ID: 35485414
Invasive brain tissue oxygen and intracranial pressure (ICP) monitoring versus ICP-only monitoring in pediatric severe traumatic brain injury.
Journal of neurosurgery. Pediatrics May, 2022 | Pubmed ID: 35623367
Novel ATXN1/ATXN1L::NUTM2A fusions identified in aggressive infant sarcomas with gene expression and methylation patterns similar to CIC-rearranged sarcoma.
Acta neuropathologica communications Jul, 2022 | Pubmed ID: 35836290
Large scalp venous malformation in a pediatric patient managed with sclerotherapy and surgery: a case report and review of literature.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Jul, 2022 | Pubmed ID: 35849142
In-Hospital Costs for Open versus Endoscopic Endonasal Approach for Craniopharyngioma Resection.
The Laryngoscope Jan, 2023 | Pubmed ID: 35929639
Reconstruction with Mucosal Graft Reduces Recurrence After Endoscopic Surgery of Rathke Cleft Cyst.
World neurosurgery Nov, 2022 | Pubmed ID: 36028104
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.
Journal for immunotherapy of cancer Sep, 2022 | Pubmed ID: 36167467
Incidence of Sinus Inflammation After Endoscopic Skull Base Surgery in the Pediatric Population.
The Laryngoscope Oct, 2022 | Pubmed ID: 36189938
Co-administration of Ketamine in Pediatric Patients with Neurologic Conditions at Risk for Intracranial Hypertension.
Neurocritical care Oct, 2022 | Pubmed ID: 36207491
Spring-mediated cranioplasty for sagittal craniosynostosis.
Neurosurgical focus: Video Apr, 2021 | Pubmed ID: 36284840
Removal of cranial springs after spring-mediated cranioplasty.
Neurosurgical focus: Video Apr, 2021 | Pubmed ID: 36284849
The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.
Neoplasia (New York, N.Y.) Jan, 2023 | Pubmed ID: 36335802
Imaging of pediatric brain tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee/ASPNR White Paper.
Pediatric blood & cancer Dec, 2022 | Pubmed ID: 36519599
ALT in Pediatric High-Grade Gliomas Can Occur without ATRX Mutation and is Enriched in Patients with Pathogenic Germline MMR Variants.
Neuro-oncology Dec, 2022 | Pubmed ID: 36541551
Unsupervised machine learning using K-means identifies radiomic subgroups of pediatric low-grade gliomas that correlate with key molecular markers.
Neoplasia (New York, N.Y.) Feb, 2023 | Pubmed ID: 36566592
Implementation of a Streamlined Care Pathway to Reduce Cost and Length of Stay for Patients Undergoing Endoscopic Transsphenoidal Pituitary Surgery.
World neurosurgery Jan, 2023 | Pubmed ID: 36640831
Retrospective dataset and survey analyses identify gaps in data collection for craniopharyngioma and priorities of patients and families affected by the disease.
Neoplasia (New York, N.Y.) Mar, 2023 | Pubmed ID: 36649671
Kyra Harvey1,
Peter J. Madsen2,3,
Tiffany Smith2,
Crystal Griffin1,2,
Luke Patterson1,2,
Nicholas A. Vitanza4,5,
Phillip B. Storm2,3,
Adam C. Resnick2,3,
Jessica B. Foster1,2
1Division of Oncology, Children’s Hospital of Philadelphia,
2Center for Data Driven Discovery in Biomedicine, Children’s Hospital of Philadelphia,
3Division of Neurosurgery, Children’s Hospital of Philadelphia,
4Ben Towne Center for Childhood Cancer Research, Seattle Children’s Research Institute,
5Department of Pediatrics, Seattle Children’s Hospital, University of Washington
SOBRE A JoVE
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