David M. Mosser

Vaccination against the intracellular pathogens Leishmania major and L. amazonensis by directing CD40 ligand to macrophages.

Cutting edge: biasing immune responses by directing antigen to macrophage Fc gamma receptors.

The modulation of macrophage activation by tyrosine phosphorylation.

A novel phenotype for an activated macrophage: the type 2 activated macrophage.

The many faces of macrophage activation.

Modulating macrophage function with IgG immune complexes.

T cell biasing by activated dendritic cells.

Innate immune responses to Rhodococcus equi.

A role for IgG immune complexes during infection with the intracellular pathogen Leishmania.

A sensitive flow cytometric methodology for studying the binding of L. chagasi to canine peritoneal macrophages.

ERK activation following macrophage FcgammaR ligation leads to chromatin modifications at the IL-10 locus.

Dynamic and transient remodeling of the macrophage IL-10 promoter during transcription.

NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages.

Biochemical and functional characterization of three activated macrophage populations.

Leishmania-derived murine monocyte chemoattractant protein 1 enhances the recruitment of a restrictive population of CC chemokine receptor 2-positive macrophages.

Activation of the MAPK, ERK, following Leishmania amazonensis infection of macrophages.

Reduced pathology following infection with transgenic Leishmania major expressing murine CD40 ligand.

Monocyte subpopulations and their differentiation patterns during infection.

NFKB1 promoter variation implicates shear-induced NOS3 gene expression and endothelial function in prehypertensives and stage I hypertensives.

Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor.

Functional characterization of bovine TIRAP and MyD88 in mediating bacterial lipopolysaccharide-induced endothelial NF-kappaB activation and apoptosis.

The isolation and characterization of murine macrophages.

Activation of murine macrophages.

Exploring the full spectrum of macrophage activation.

Interleukin-10: new perspectives on an old cytokine.

The expression of heparin-binding epidermal growth factor-like growth factor by regulatory macrophages.

The expression of exogenous genes in macrophages: obstacles and opportunities.

The influence of IgG density and macrophage Fc (gamma) receptor cross-linking on phagocytosis and IL-10 production.

Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes.

The regulation of Th1 responses by the p38 MAPK.

The neonatal FcR-mediated presentation of immune-complexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells.

Platelet activation attracts a subpopulation of effector monocytes to sites of Leishmania major infection.

Regulatory macrophages: setting the threshold for therapy.

Editorial: switching on arginase in M2 macrophages.

Measuring opsonic phagocytosis via Fcγ receptors and complement receptors on macrophages.

TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses.

Extrinsic and intrinsic control of macrophage inflammatory responses.

Pattern recognition receptors in innate immunity, host defense, and immunopathology.

Cardiac macrophages: how to mend a broken heart.

Macrophage activation and polarization: nomenclature and experimental guidelines.

IL-18 contributes to susceptibility to Leishmania amazonensis infection by macrophage-independent mechanisms.

The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.

Transcriptomic profiling of gene expression and RNA processing during Leishmania major differentiation.

Upregulated IL-1β in dysferlin-deficient muscle attenuates regeneration by blunting the response to pro-inflammatory macrophages.

IFN-γ Prevents Adenosine Receptor (A2bR) Upregulation To Sustain the Macrophage Activation Response.

Simultaneous transcriptional profiling of Leishmania major and its murine macrophage host cell reveals insights into host-pathogen interactions.

Purinergic Signaling to Terminate TLR Responses in Macrophages.

Complement-mediated 'bystander' damage initiates host NLRP3 inflammasome activation.

Dual Transcriptome Profiling of Leishmania-Infected Human Macrophages Reveals Distinct Reprogramming Signatures.

OPN-a induces muscle inflammation by increasing recruitment and activation of pro-inflammatory macrophages.

Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion.

Macrophages and the Recovery from Acute and Chronic Inflammation.

Using a Concept Inventory to Reveal Student Thinking Associated with Common Misconceptions about Antibiotic Resistance.

Monocyte subpopulations as important biomarkers of resistence and susceptibility during experimental infection with Leishmania (Leishmania) major.

Host and parasite responses in human diffuse cutaneous leishmaniasis caused by L. amazonensis.

Regulatory Macrophages Inhibit Alternative Macrophage Activation and Attenuate Pathology Associated with Fibrosis.

Immunohistochemical study of renal fibropoiesis associated with dogs naturally and experimentally infected with two different strains of Leishmania (L.) infantum.

Immune Complex-Driven Generation of Human Macrophages with Anti-Inflammatory and Growth-Promoting Activity.

Macrophage polarization in intestinal inflammation and gut homeostasis.

Macrophages and the maintenance of homeostasis.

The transition of M-CSF-derived human macrophages to a growth-promoting phenotype.

High-Density-Immune-Complex Regulatory Macrophages Promote Recovery of Experimental Colitis in Mice.

Humoral immunity in leishmaniasis - Prevention or promotion of parasite growth?

Skin fibrosis associated with keloid, scleroderma and Jorge Lobo's disease (lacaziosis): An immuno-histochemical study.