Department of Biomedical Sciences,
Faculty of Health and Medical Sciences,
NNF Center for Basic Metabolic Research,
Department of Biomedical Sciences, Faculty of Health and Medical Sciences,
NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences
Jens Juul Holst has not added Biography.
If you are Jens Juul Holst and would like to personalize this page please email our Author Liaison for assistance.
Differential postprandial lipoprotein responses in type 2 diabetic men with and without clinical evidence of a former myocardial infarction.
The review of diabetic studies : RDS , 2004 | Pubmed ID: 17491702
Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery , 2007 | Pubmed ID: 17936091
Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans.
Diabetes Sep, 2010 | Pubmed ID: 20547981
Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function.
Diabetes care Jul, 2011 | Pubmed ID: 21593296
The Effect of Dietary Fish Oil in addition to Lifestyle Counselling on Lipid Oxidation and Body Composition in Slightly Overweight Teenage Boys.
Journal of nutrition and metabolism , 2011 | Pubmed ID: 21773017
Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks' sucrose-rich diet compared to an artificially sweetened diet: a randomised controlled trial.
Food & nutrition research , 2011 | Pubmed ID: 21799667
Postprandial insulin secretion after gastric bypass surgery: the role of glucagon-like peptide 1.
Diabetes Sep, 2011 | Pubmed ID: 21868790
Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain.
The Journal of biological chemistry Dec, 2011 | Pubmed ID: 22027838
Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs.
JPEN. Journal of parenteral and enteral nutrition Sep, 2012 | Pubmed ID: 22549765
Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Dec, 2012 | Pubmed ID: 22929437
Influence of erythropoietin on cognitive performance during experimental hypoglycemia in patients with type 1 diabetes mellitus: a randomized cross-over trial.
PloS one , 2013 | Pubmed ID: 23577069
Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol.
BMC cardiovascular disorders Nov, 2013 | Pubmed ID: 24252596
Glucagon-like peptide-1: effect on pro-atrial natriuretic peptide in healthy males.
Endocrine connections , 2014 | Pubmed ID: 24327600
Influence of GLP-1 on myocardial glucose metabolism in healthy men during normo- or hypoglycemia.
PloS one , 2014 | Pubmed ID: 24400077
GLP-1 amidation efficiency along the length of the intestine in mice, rats and pigs and in GLP-1 secreting cell lines.
Peptides May, 2014 | Pubmed ID: 24486427
Does a GLP-1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications? Design of a randomised, double-blinded, placebo-controlled clinical trial.
BMJ open Mar, 2014 | Pubmed ID: 24667381
Effects of PYY3-36 and GLP-1 on energy intake, energy expenditure, and appetite in overweight men.
American journal of physiology. Endocrinology and metabolism Jun, 2014 | Pubmed ID: 24735885
The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract.
Scandinavian journal of gastroenterology Sep, 2014 | Pubmed ID: 24998781
Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely.
Appetite Nov, 2014 | Pubmed ID: 25049132
Effects of angiotensin II receptor blockade on cerebral, cardiovascular, counter-regulatory, and symptomatic responses during hypoglycaemia in patients with type 1 diabetes.
Journal of the renin-angiotensin-aldosterone system : JRAAS Dec, 2015 | Pubmed ID: 25070348
High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals.
Nutrition research (New York, N.Y.) Aug, 2014 | Pubmed ID: 25172378
Updates in weight loss surgery and gastrointestinal peptides.
Current opinion in endocrinology, diabetes, and obesity Feb, 2015 | Pubmed ID: 25517025
An analysis of cosecretion and coexpression of gut hormones from male rat proximal and distal small intestine.
Endocrinology Mar, 2015 | Pubmed ID: 25535831
A 25-year-old woman with type 2 diabetes and liver disease.
Case reports in gastroenterology , 2014 | Pubmed ID: 25606030
Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide.
Journal of diabetes and its complications Apr, 2015 | Pubmed ID: 25623632
Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol.
The Journal of physiology Apr, 2015 | Pubmed ID: 25639597
GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study.
Diabetes Jul, 2015 | Pubmed ID: 25677912
Efficacy and safety of the glucagon-like peptide-1 receptor agonist liraglutide added to insulin therapy in poorly regulated patients with type 1 diabetes--a protocol for a randomised, double-blind, placebo-controlled study: the Lira-1 study.
BMJ open Apr, 2015 | Pubmed ID: 25838513
Preoperative β-cell function in patients with type 2 diabetes is important for the outcome of Roux-en-Y gastric bypass surgery.
The Journal of physiology Jul, 2015 | Pubmed ID: 25867961
Glucose stimulates neurotensin secretion from the rat small intestine by mechanisms involving SGLT1 and GLUT2, leading to cell depolarization and calcium influx.
American journal of physiology. Endocrinology and metabolism Jun, 2015 | Pubmed ID: 25898949
Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young.
European journal of endocrinology Aug, 2015 | Pubmed ID: 25953829
Liraglutide for Type 2 diabetes and obesity: a 2015 update.
Expert review of cardiovascular therapy , 2015 | Pubmed ID: 26106933
The anorexic hormone Peptide YY3-36 is rapidly metabolized to inactive Peptide YY3-34 in vivo.
Physiological reports Jul, 2015 | Pubmed ID: 26197931
Specific inhibition of bile acid transport alters plasma lipids and GLP-1.
BMC cardiovascular disorders Jul, 2015 | Pubmed ID: 26197999
GLP1 and glucagon co-secreting pancreatic neuroendocrine tumor presenting as hypoglycemia after gastric bypass.
Endocrinology, diabetes & metabolism case reports , 2015 | Pubmed ID: 26266036
Regulation of gut hormone secretion. Studies using isolated perfused intestines.
Peptides Mar, 2016 | Pubmed ID: 26275337
Gastric emptying and disease activity in inflammatory bowel disease.
European journal of clinical investigation Dec, 2015 | Pubmed ID: 26426315
Effect of Oxyntomodulin, Glucagon, GLP-1, and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite, and Resting Energy Expenditure.
The Journal of clinical endocrinology and metabolism Dec, 2015 | Pubmed ID: 26445112
Inability to match energy intake with energy expenditure at sustained near-maximal rates of energy expenditure in older men during a 14-d cycling expedition.
The American journal of clinical nutrition Dec, 2015 | Pubmed ID: 26490491
Glucose-Dependent Insulinotropic Polypeptide Is Associated With Lower Low-Density Lipoprotein But Unhealthy Fat Distribution, Independent of Insulin: The ADDITION-PRO Study.
The Journal of clinical endocrinology and metabolism Feb, 2016 | Pubmed ID: 26505824
Resistant starch and protein intake enhances fat oxidation and feelings of fullness in lean and overweight/obese women.
Nutrition journal Oct, 2015 | Pubmed ID: 26514213
Efficacy and safety of liraglutide for overweight adult patients with type 1 diabetes and insufficient glycaemic control (Lira-1): a randomised, double-blind, placebo-controlled trial.
The lancet. Diabetes & endocrinology Mar, 2016 | Pubmed ID: 26656289
Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men.
PloS one , 2016 | Pubmed ID: 26752550
Do glucagonomas always produce glucagon?
Bosnian journal of basic medical sciences Feb, 2016 | Pubmed ID: 26773171
In vivo and in vitro degradation of peptide YY3-36 to inactive peptide YY3-34 in humans.
American journal of physiology. Regulatory, integrative and comparative physiology May, 2016 | Pubmed ID: 26818056
Peptide production and secretion in GLUTag, NCI-H716, and STC-1 cells: a comparison to native L-cells.
Journal of molecular endocrinology Apr, 2016 | Pubmed ID: 26819328
Rapid gut growth but persistent delay in digestive function in the postnatal period of preterm pigs.
American journal of physiology. Gastrointestinal and liver physiology Apr, 2016 | Pubmed ID: 26822913
Major rapid weight loss induces changes in cardiac repolarization.
Journal of electrocardiology , 2016 | Pubmed ID: 26925492
Liraglutide for treating type 1 diabetes.
Expert opinion on biological therapy , 2016 | Pubmed ID: 26926662
Cholecystokinin-Induced Gallbladder Emptying and Metformin Elicit Additive Glucagon-Like Peptide-1 Responses.
The Journal of clinical endocrinology and metabolism May, 2016 | Pubmed ID: 27003305
The insulinotropic effect of exogenous glucagon-like peptide-1 is not affected by acute vagotomy in anaesthetized pigs.
Experimental physiology Jul, 2016 | Pubmed ID: 27027735
Searching for the physiological role of glucose-dependent insulinotropic polypeptide.
Journal of diabetes investigation Apr, 2016 | Pubmed ID: 27186349
Type 2 diabetes mellitus.
Nature reviews. Disease primers Jul, 2015 | Pubmed ID: 27189025
Roles of the Gut in Glucose Homeostasis.
Diabetes care Jun, 2016 | Pubmed ID: 27222546
Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans.
The Journal of clinical endocrinology and metabolism Aug, 2016 | Pubmed ID: 27258938
Mechanisms of surgical control of type 2 diabetes: GLP-1 is key factor.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery Jul, 2016 | Pubmed ID: 27313194
Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro.
Endocrinology Oct, 2016 | Pubmed ID: 27479530
Insulin Resistance Is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation.
Diabetes Nov, 2016 | Pubmed ID: 27504013
Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells.
Cell reports Aug, 2016 | Pubmed ID: 27545881
Low-Carbohydrate Diet Impairs the Effect of Glucagon in the Treatment of Insulin-Induced Mild Hypoglycemia: A Randomized Crossover Study.
Diabetes care Jan, 2017 | Pubmed ID: 27797928
Effect of Liraglutide Treatment on Jejunostomy Output in Patients With Short Bowel Syndrome: An Open-Label Pilot Study.
JPEN. Journal of parenteral and enteral nutrition Jan, 2018 | Pubmed ID: 27875281
Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome.
European journal of nutrition Mar, 2018 | Pubmed ID: 28070639
Hypoglycemia-Associated EEG Changes Following Antecedent Hypoglycemia in Type 1 Diabetes Mellitus.
Diabetes technology & therapeutics Feb, 2017 | Pubmed ID: 28118048
Differential impact of glucose administered intravenously or orally on bone turnover markers in healthy male subjects.
Bone Apr, 2017 | Pubmed ID: 28126633
Acute effects of glucagon-like peptide-1, GLP-1, and exenatide on mesenteric blood flow, cardiovascular parameters, and biomarkers in healthy volunteers.
Physiological reports Feb, 2017 | Pubmed ID: 28235974
Preserved glucagon-like peptide-1 responses to oral glucose, but reduced incretin effect, insulin secretion and sensitivity in young Asians with type 2 diabetes mellitus.
BMJ open diabetes research & care , 2017 | Pubmed ID: 28321312
Insulin and Glucagon: Partners for Life.
Endocrinology Apr, 2017 | Pubmed ID: 28323959
Short-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trial.
Diabetes, obesity & metabolism Oct, 2017 | Pubmed ID: 28345762
Effect of oral contraceptives and/or metformin on GLP-1 secretion and reactive hypoglycaemia in polycystic ovary syndrome.
Endocrine connections May, 2017 | Pubmed ID: 28432082
The Gut: A Key to the Pathogenesis of Type 2 Diabetes?
Metabolic syndrome and related disorders Aug, 2017 | Pubmed ID: 28605280
Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes.
Journal of diabetes science and technology Nov, 2017 | Pubmed ID: 28654314
The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor.
Diabetes Sep, 2017 | Pubmed ID: 28667118
DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity.
PloS one , 2017 | Pubmed ID: 28750074
Genetic determinants of circulating GIP and GLP-1 concentrations.
JCI insight Nov, 2017 | Pubmed ID: 29093273
Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial.
Gut Jan, 2019 | Pubmed ID: 29097438
Glucagon-Like Peptide-1 Inhibits Prandial Gastrointestinal Motility Through Myenteric Neuronal Mechanisms in Humans.
The Journal of clinical endocrinology and metabolism Feb, 2018 | Pubmed ID: 29177486
Discovery, characterization, and clinical development of the glucagon-like peptides.
The Journal of clinical investigation Dec, 2017 | Pubmed ID: 29202475
Instrumentalization of Eating Improves Weight Loss Maintenance in Obesity.
Obesity facts , 2017 | Pubmed ID: 29207396
Glucagon-like peptide-1 acutely affects renal blood flow and urinary flow rate in spontaneously hypertensive rats despite significantly reduced renal expression of GLP-1 receptors.
Physiological reports Dec, 2017 | Pubmed ID: 29233907
Semaglutide seems to be more effective the other GLP-1Ras.
Annals of translational medicine Dec, 2017 | Pubmed ID: 29299466
Comparing olive oil and C4-dietary oil, a prodrug for the GPR119 agonist, 2-oleoyl glycerol, less energy intake of the latter is needed to stimulate incretin hormone secretion in overweight subjects with type 2 diabetes.
Nutrition & diabetes 01, 2018 | Pubmed ID: 29330461
Effects of Preceding Ethanol Intake on Glucose Response to Low-Dose Glucagon in Individuals With Type 1 Diabetes: A Randomized, Placebo-Controlled, Crossover Study.
Diabetes care Apr, 2018 | Pubmed ID: 29358493
Pre-Meal Effect of Whey Proteins on Metabolic Parameters in Subjects with and without Type 2 Diabetes: A Randomized, Crossover Trial.
Nutrients Jan, 2018 | Pubmed ID: 29370144
Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents.
Peptides Feb, 2018 | Pubmed ID: 29412817
The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon.
American journal of physiology. Gastrointestinal and liver physiology Jul, 2018 | Pubmed ID: 29494208
Comparison of Glycomacropeptide with Phenylalanine Free-Synthetic Amino Acids in Test Meals to PKU Patients: No Significant Differences in Biomarkers, Including Plasma Phe Levels.
Journal of nutrition and metabolism , 2018 | Pubmed ID: 29511574
Hemodynamic Effects of Glucagon: A Literature Review.
The Journal of clinical endocrinology and metabolism May, 2018 | Pubmed ID: 29546411
Erratum to semaglutide seems to be more effective the other GLP-1Ras.
Annals of translational medicine Feb, 2018 | Pubmed ID: 29611550
A pre-meal of whey proteins induces differential effects on glucose and lipid metabolism in subjects with the metabolic syndrome: a randomised cross-over trial.
European journal of nutrition Mar, 2019 | Pubmed ID: 29626232
Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control.
Cell metabolism Jun, 2018 | Pubmed ID: 29731416
WITHDRAWN: Glucose-Dependent Insulinotropic Polypeptide Increases Blood Flow in Adipose Tissue of Humans by Recruiting Capillaries.
The Journal of clinical endocrinology and metabolism Jan, 2019 | Pubmed ID: 29750414
Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 05, 2018 | Pubmed ID: 29776493
Endogenous glucagon-like peptide- 1 and 2 are essential for regeneration after acute intestinal injury in mice.
PloS one , 2018 | Pubmed ID: 29864142
Non-insulin pharmacological therapies for treating type 1 diabetes.
Expert opinion on pharmacotherapy Jun, 2018 | Pubmed ID: 29991320
Patient profiling for success after weight loss surgery (GO Bypass study): An interdisciplinary study protocol.
Contemporary clinical trials communications Jun, 2018 | Pubmed ID: 30023446
Acute Effects of Dietary Carbohydrate Restriction on Glycemia, Lipemia and Appetite Regulating Hormones in Normal-Weight to Obese Subjects.
Nutrients Sep, 2018 | Pubmed ID: 30213037
Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review".
The Journal of clinical endocrinology and metabolism Dec, 2018 | Pubmed ID: 30239764
Hepatic Insulin Clearance in Regulation of Systemic Insulin Concentrations-Role of Carbohydrate and Energy Availability.
Diabetes Nov, 2018 | Pubmed ID: 30348819
Insulin Secretion Depends on Intra-islet Glucagon Signaling.
Cell reports Oct, 2018 | Pubmed ID: 30380405
Effects of glucagon-like peptide 1 analogs on alcohol intake in alcohol-preferring vervet monkeys.
Psychopharmacology Feb, 2019 | Pubmed ID: 30382353
A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults.
Nature communications Nov, 2018 | Pubmed ID: 30425247
Neuromedin U Does Not Act as a Decretin in Rats.
Cell metabolism Nov, 2018 | Pubmed ID: 30449683
Pre-meal and postprandial lipaemia in subjects with the metabolic syndrome: effects of timing and protein quality (randomised crossover trial).
The British journal of nutrition Feb, 2019 | Pubmed ID: 30599817
Effects of active commuting and leisure-time exercise on appetite in individuals with overweight and obesity.
Journal of applied physiology (Bethesda, Md. : 1985) Jan, 2019 | Pubmed ID: 30605397
Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients.
The Journal of clinical endocrinology and metabolism Feb, 2019 | Pubmed ID: 30726969
Glucagon-Like Peptide-1 Is a Marker of Systemic Inflammation in Patients Treated with High-Dose Chemotherapy and Autologous Stem Cell Transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Jun, 2019 | Pubmed ID: 30731250
The effect of DPP-4-protected GLP-1 (7-36) on coronary microvascular function in obese adults.
International journal of cardiology. Heart & vasculature Mar, 2019 | Pubmed ID: 30740510
Postprandial Nutrient Handling and Gastrointestinal Secretion of Hormones After Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy.
Gastroenterology Feb, 2019 | Pubmed ID: 30742833
Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents.
American journal of physiology. Gastrointestinal and liver physiology Feb, 2019 | Pubmed ID: 30767682
Effect of liraglutide on body weight and microvascular function in non-diabetic overweight women with coronary microvascular dysfunction.
International journal of cardiology May, 2019 | Pubmed ID: 30773266
Augmented GLP-1 Secretion as Seen After Gastric Bypass May Be Obtained by Delaying Carbohydrate Digestion.
The Journal of clinical endocrinology and metabolism Aug, 2019 | Pubmed ID: 30844053
Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men Without Diabetes.
The Journal of clinical endocrinology and metabolism Jul, 2019 | Pubmed ID: 30848791
Gut Hormones and Their Effect on Bone Metabolism. Potential Drug Therapies in Future Osteoporosis Treatment.
Frontiers in endocrinology , 2019 | Pubmed ID: 30863364
No direct effect of SGLT2 activity on glucagon secretion.
Diabetologia Jun, 2019 | Pubmed ID: 30903205
Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia.
Obesity surgery Jul, 2019 | Pubmed ID: 30976983
Long-acting glucagon-like peptide-1 receptor agonist-status December 2018.
Annals of translational medicine Mar, 2019 | Pubmed ID: 31019933
Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located Calcium-Sensing Receptors.
Physiological reports Apr, 2019 | Pubmed ID: 31020803
The incretin system in healthy humans: The role of GIP and GLP-1.
Metabolism: clinical and experimental Jul, 2019 | Pubmed ID: 31029770
Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes.
Frontiers in endocrinology , 2019 | Pubmed ID: 31031712
Postprandial levels of GLP-1, GIP and glucagon after 2 years of weight loss with a Paleolithic diet: a randomised controlled trial in healthy obese women.
European journal of endocrinology Jun, 2019 | Pubmed ID: 31042670
GIP-induced vasodilation in human adipose tissue involves capillary recruitment.
Endocrine connections Jun, 2019 | Pubmed ID: 31063975
From the Incretin Concept and the Discovery of GLP-1 to Today's Diabetes Therapy.
Frontiers in endocrinology , 2019 | Pubmed ID: 31080438
Postprandial hypoglycaemia after Roux-en-Y gastric bypass and the effects of acarbose, sitagliptin, verapamil, liraglutide and pasireotide.
Diabetes, obesity & metabolism Sep, 2019 | Pubmed ID: 31144430
Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease.
Diabetology & metabolic syndrome , 2019 | Pubmed ID: 31164926
Which to choose, an oral or an injectable glucagon-like peptide-1 receptor agonist?
Lancet (London, England) Jul, 2019 | Pubmed ID: 31186119
The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes.
European journal of endocrinology Sep, 2019 | Pubmed ID: 31189129
Pros and cons of Roux en-Y gastric bypass surgery in obese patients with type 2 diabetes.
Expert review of endocrinology & metabolism Jul, 2019 | Pubmed ID: 31215828
The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake.
EBioMedicine Aug, 2019 | Pubmed ID: 31383551
Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats.
Frontiers in endocrinology , 2019 | Pubmed ID: 31447774
Short-chain fatty acids and regulation of pancreatic endocrine secretion in mice.
Islets , 2019 | Pubmed ID: 31469342
Effects of a High-Protein/Moderate-Carbohydrate Diet on Appetite, Gut Peptides, and Endocannabinoids-A Preview Study.
Nutrients Sep, 2019 | Pubmed ID: 31546629
Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1.
The Journal of clinical endocrinology and metabolism Jan, 2020 | Pubmed ID: 31608930
Effects of Exercise Training and IL-6 Receptor Blockade on Gastric Emptying and GLP-1 Secretion in Obese Humans: Secondary Analyses From a Double Blind Randomized Clinical Trial.
Frontiers in physiology , 2019 | Pubmed ID: 31636570
Methods and Guidelines for Measurement of Glucagon in Plasma.
International journal of molecular sciences Oct, 2019 | Pubmed ID: 31671667
Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-calorie diet.
BMJ open Nov, 2019 | Pubmed ID: 31678947
A Pilot Study Showing Acute Inhibitory Effect of GLP-1 on the Bone Resorption Marker CTX in Humans.
JBMR plus Oct, 2019 | Pubmed ID: 31687645
A Low Dose of Pasireotide Prevents Hypoglycemia in Roux-en-Y Gastric Bypass-Operated Individuals.
Obesity surgery Apr, 2020 | Pubmed ID: 31709494
Correction to: Effects of glucagon-like peptide 1 analogs on alcohol intake in alcohol-preferring vervet monkeys.
Psychopharmacology Jan, 2020 | Pubmed ID: 31768561
Incretin therapy for diabetes mellitus type 2.
Current opinion in endocrinology, diabetes, and obesity Feb, 2020 | Pubmed ID: 31815785
Recent advances of GIP and future horizons.
Peptides Mar, 2020 | Pubmed ID: 31838219
Evidence for Relationship Between Early Dumping and Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass.
Obesity surgery Mar, 2020 | Pubmed ID: 31907828
Consumption of nutrients and insulin resistance suppress markers of bone turnover in subjects with abdominal obesity.
Bone Apr, 2020 | Pubmed ID: 31954199
Glucagon-Like Peptide 1 and Atrial Natriuretic Peptide in a Female Mouse Model of Obstructive Pulmonary Disease.
Journal of the Endocrine Society Jan, 2020 | Pubmed ID: 32010874
Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine.
International journal of obesity (2005) Sep, 2020 | Pubmed ID: 32015474
Oxyntomodulin and Glicentin May Predict the Effect of Bariatric Surgery on Food Preferences and Weight Loss.
The Journal of clinical endocrinology and metabolism Apr, 2020 | Pubmed ID: 32016415
Nutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs.
The Journal of nutrition May, 2020 | Pubmed ID: 32069355
Gain-of-function mutation in the voltage-gated potassium channel gene KCNQ1 and glucose-stimulated hypoinsulinemia - case report.
BMC endocrine disorders Mar, 2020 | Pubmed ID: 32164657
Proglucagon peptide secretion profiles in type 2 diabetes before and after bariatric surgery: 1-year prospective study.
BMJ open diabetes research & care Mar, 2020 | Pubmed ID: 32209584
Changes in the Homeostatic Appetite System After Weight Loss Reflect a Normalization Toward a Lower Body Weight.
The Journal of clinical endocrinology and metabolism Jul, 2020 | Pubmed ID: 32301981
Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2-dependent pathway in mice.
American journal of physiology. Gastrointestinal and liver physiology May, 2020 | Pubmed ID: 32308039
Predictors of weight loss after bariatric surgery-a cross-disciplinary approach combining physiological, social, and psychological measures.
International journal of obesity (2005) Nov, 2020 | Pubmed ID: 32327722
Effects of a highly controlled carbohydrate-reduced high-protein diet on markers of oxidatively generated nucleic acid modifications and inflammation in weight stable participants with type 2 diabetes; a randomized controlled trial.
Scandinavian journal of clinical and laboratory investigation Sep, 2020 | Pubmed ID: 32374188
GIP as a Therapeutic Target in Diabetes and Obesity: Insight From Incretin Co-agonists.
The Journal of clinical endocrinology and metabolism Aug, 2020 | Pubmed ID: 32459834
Secretion of parathyroid hormone may be coupled to insulin secretion in humans.
Endocrine connections Jul, 2020 | Pubmed ID: 32698134
Oral D/L-3-Hydroxybutyrate Stimulates Cholecystokinin and Insulin Secretion and Slows Gastric Emptying in Healthy Males.
The Journal of clinical endocrinology and metabolism Oct, 2020 | Pubmed ID: 32717058
Preserved postprandial suppression of bone turnover markers, despite increased fasting levels, in postmenopausal women.
Bone Feb, 2021 | Pubmed ID: 32853851
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis.
Molecular metabolism Dec, 2020 | Pubmed ID: 32937194
Effects of whey protein and dietary fiber intake on insulin sensitivity, body composition, energy expenditure, blood pressure, and appetite in subjects with abdominal obesity.
European journal of clinical nutrition Apr, 2021 | Pubmed ID: 32948867
Counterregulatory responses to postprandial hypoglycemia after Roux-en-Y gastric bypass.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery Jan, 2021 | Pubmed ID: 33039341
Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets.
Diabetologia Jan, 2021 | Pubmed ID: 33043402
Nonalcoholic Fatty Liver Disease Impairs the Liver-Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis.
Hepatology communications Nov, 2020 | Pubmed ID: 33163832
Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness.
Diabetes care Jan, 2021 | Pubmed ID: 33208488
Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice; Extremely rapid degradation but marked variation between available assays.
Peptides Feb, 2021 | Pubmed ID: 33245951
The effect of preceding glucose decline rate on low-dose glucagon efficacy in individuals with type 1 diabetes: A randomized crossover trial.
Diabetes, obesity & metabolism Apr, 2021 | Pubmed ID: 33336888
Incretin Hormones and Type 2 Diabetes-Mechanistic Insights and Therapeutic Approaches.
Biology Dec, 2020 | Pubmed ID: 33339298
Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test.
BMC medical genomics Jan, 2021 | Pubmed ID: 33407418
Effect of 6 weeks of very low-volume high-intensity interval training on oral glucose-stimulated incretin hormone response.
European journal of sport science Mar, 2022 | Pubmed ID: 33461430
What is Diabetes Remission?
Diabetes therapy : research, treatment and education of diabetes and related disorders Mar, 2021 | Pubmed ID: 33609265
Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms.
American journal of physiology. Endocrinology and metabolism May, 2021 | Pubmed ID: 33645250
GIP receptor deletion in mice confers resistance to high-fat diet-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism.
American journal of physiology. Endocrinology and metabolism Apr, 2021 | Pubmed ID: 33645252
β-Lactoglobulin Is Insulinotropic Compared with Casein and Whey Protein Ingestion during Catabolic Conditions in Men in a Double-Blinded Randomized Crossover Trial.
The Journal of nutrition Jun, 2021 | Pubmed ID: 33693737
In patients with controlled acromegaly, indices of glucose homeostasis correlate with IGF-1 levels rather than with type of treatment.
Clinical endocrinology Jul, 2021 | Pubmed ID: 33715210
Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice.
Frontiers in endocrinology , 2021 | Pubmed ID: 33716991
The Role of Incretins on Insulin Function and Glucose Homeostasis.
Endocrinology Jul, 2021 | Pubmed ID: 33782700
The Antiresorptive Effect of GIP, But Not GLP-2, Is Preserved in Patients With Hypoparathyroidism-A Randomized Crossover Study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Aug, 2021 | Pubmed ID: 33852173
Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography.
BMJ open diabetes research & care Apr, 2021 | Pubmed ID: 33903116
GLP-1 and Intestinal Diseases.
Biomedicines Apr, 2021 | Pubmed ID: 33916501
Sitagliptin, a dipeptidyl peptidase-4 inhibitor, in patients with short bowel syndrome and colon in continuity: an open-label pilot study.
BMJ open gastroenterology May, 2021 | Pubmed ID: 33975891
What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?
Cell reports. Medicine May, 2021 | Pubmed ID: 34095885
Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors.
Frontiers in endocrinology , 2021 | Pubmed ID: 34108943
Subcutaneous GIP and GLP-2 inhibit nightly bone resorption in postmenopausal women: A preliminary study.
Bone Nov, 2021 | Pubmed ID: 34153529
Actions of glucagon-like peptide-1 receptor ligands in the gut.
British journal of pharmacology Feb, 2022 | Pubmed ID: 34235727
The Effect of Melatonin on Incretin Hormones: Results From Experimental and Randomized Clinical Studies.
The Journal of clinical endocrinology and metabolism Nov, 2021 | Pubmed ID: 34265066
Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals.
American journal of physiology. Endocrinology and metabolism Oct, 2021 | Pubmed ID: 34370594
The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes.
Endocrine connections Sep, 2021 | Pubmed ID: 34382579
Effects of a Lifestyle Intervention on Bone Turnover in Persons with Type 2 Diabetes: A Post Hoc Analysis of the U-TURN Trial.
Medicine and science in sports and exercise Jan, 2022 | Pubmed ID: 34431828
Gastrointestinal Hormones and β-Cell Function After Gastric Bypass and Sleeve Gastrectomy: A Randomized Controlled Trial (Oseberg).
The Journal of clinical endocrinology and metabolism Jan, 2022 | Pubmed ID: 34463768
Colonic Lactulose Fermentation Has No Impact on Glucagon-like Peptide-1 and Peptide-YY Secretion in Healthy Young Men.
The Journal of clinical endocrinology and metabolism Jan, 2022 | Pubmed ID: 34508600
Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture.
Diabetes Nov, 2021 | Pubmed ID: 34711671
The incretin/glucagon system as a target for pharmacotherapy of obesity.
Obesity reviews : an official journal of the International Association for the Study of Obesity Feb, 2022 | Pubmed ID: 34713962
Peptides in the regulation of glucagon secretion.
Peptides Feb, 2022 | Pubmed ID: 34748791
Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation.
Frontiers in immunology , 2021 | Pubmed ID: 34956226
GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment.
Pharmacological research Feb, 2022 | Pubmed ID: 34995796
GLP-1 - Incretin and pleiotropic hormone with pharmacotherapy potential. Increasing secretion of endogenous GLP-1 for diabetes and obesity therapy.
Current opinion in pharmacology Apr, 2022 | Pubmed ID: 35231672
Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats.
Diabetologia Jun, 2022 | Pubmed ID: 35325259
Extreme duration exercise affects old and younger men differently.
Acta physiologica (Oxford, England) Jul, 2022 | Pubmed ID: 35347845
Early effects of Roux-en-Y gastric bypass on dietary fatty acid absorption and metabolism in people with obesity and normal glucose tolerance.
International journal of obesity (2005) Jul, 2022 | Pubmed ID: 35459799
N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction.
British journal of pharmacology Sep, 2022 | Pubmed ID: 35523760
Impact of Polymorphism in the β2-Receptor Gene on Metabolic Responses to Repeated Hypoglycemia in Healthy Humans.
The Journal of clinical endocrinology and metabolism Jul, 2022 | Pubmed ID: 35552407
The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion.
Metabolites May, 2022 | Pubmed ID: 35629924
Discovery of the GI Effects of GLP-1: An Historical Perspective.
Digestive diseases and sciences Jul, 2022 | Pubmed ID: 35635627
Glucagon-like peptide-1 effect on β-cell function varies according to diabetes remission status after Roux-en-Y gastric bypass.
Diabetes, obesity & metabolism Nov, 2022 | Pubmed ID: 35676799
Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A randomised controlled trial.
Clinical nutrition (Edinburgh, Scotland) Jul, 2022 | Pubmed ID: 35679680
Glucose-dependent insulinotropic polypeptide receptor antagonist treatment causes a reduction in weight gain in ovariectomised high fat diet-fed mice.
British journal of pharmacology Sep, 2022 | Pubmed ID: 35710141
The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection.
Frontiers in endocrinology , 2022 | Pubmed ID: 35846282
Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: protocol for the HyperCarD2 randomised, crossover trial.
BMJ open Aug, 2022 | Pubmed ID: 35953245
Exploratory analysis of eating- and physical activity-related outcomes from a randomized controlled trial for weight loss maintenance with exercise and liraglutide single or combination treatment.
Nature communications Aug, 2022 | Pubmed ID: 35970829
Reply - Letter to the editor - On carbohydrate restriction and health-related quality of life and cognition in type 2 diabetes.
Clinical nutrition (Edinburgh, Scotland) Sep, 2022 | Pubmed ID: 35981924
Glucagon and other proglucagon-derived peptides in the pathogenesis of obesity.
Frontiers in nutrition , 2022 | Pubmed ID: 35990325
Exenatide once weekly for alcohol use disorder investigated in a randomized, placebo-controlled clinical trial.
JCI insight Oct, 2022 | Pubmed ID: 36066977
GIP Affects Hepatic Fat and Brown Adipose Tissue Thermogenesis but Not White Adipose Tissue Transcriptome in Type 1 Diabetes.
The Journal of clinical endocrinology and metabolism Nov, 2022 | Pubmed ID: 36111559
Prolonged lipopolysaccharide-induced illness elevates glucagon-like peptide-1 and suppresses peptide YY: A human-randomized cross-over trial.
Physiological reports Sep, 2022 | Pubmed ID: 36117310
Metabolic Dysregulation in Adult Survivors of Pediatric Hematopoietic Stem Cell Transplantation: The Role of Incretins.
The Journal of clinical endocrinology and metabolism Jan, 2023 | Pubmed ID: 36181459
Evaluation of commercially available glucagon receptor antibodies and glucagon receptor expression.
Communications biology Nov, 2022 | Pubmed ID: 36418521
Gastrointestinal hormones and appetite ratings after weight loss induced by diet or bariatric surgery.
Obesity (Silver Spring, Md.) Feb, 2023 | Pubmed ID: 36536482
Endogenous incretin levels and risk of first incident cancer: a prospective cohort study.
Scientific reports Jan, 2023 | Pubmed ID: 36611045
Glucagon 100 years. Important, but still enigmatic.
Peptides Mar, 2023 | Pubmed ID: 36626940
Incretin-based therapy of metabolic disease.
Danish medical journal Dec, 2022 | Pubmed ID: 36629298
Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice.
British journal of pharmacology Jul, 2023 | Pubmed ID: 36683195
Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones.
Molecular metabolism Mar, 2023 | Pubmed ID: 36739969
Increased meal-induced neurotensin response predicts successful maintenance of weight loss - Data from a randomized controlled trial.
Metabolism: clinical and experimental Jun, 2023 | Pubmed ID: 36933790
Effects of aerobic training and semaglutide treatment on pancreatic β-cell secretory function in patients with type 2 diabetes.
The Journal of clinical endocrinology and metabolism Jun, 2023 | Pubmed ID: 37265222
Post-prandial secretion of glucagon-like peptide-2 (GLP-2) after carbohydrate-, fat- or protein enriched meals in healthy subjects.
Peptides Nov, 2023 | Pubmed ID: 37640265
Primary weight loss failure after Roux-en-Y gastric bypass is characterized by impaired gut-hormone mediated regulation of food intake.
International journal of obesity (2005) Aug, 2023 | Pubmed ID: 37653071
Unravelling Effects of Rosemary ( L.) Extract on Hepatic Fat Accumulation and Plasma Lipid Profile in Rats Fed a High-Fat Western-Style Diet.
Metabolites Aug, 2023 | Pubmed ID: 37755254
Marie Winther-Sørensen1,2,3,
Ida Marie Kemp1,3,
Hanne Cathrine Bisgaard4,
Jens Juul Holst1,5,
Nicolai J. Wewer Albrechtsen2,3
1Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen,
2NNF Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen,
3Department for Clinical Biochemistry, Copenhagen University Hospital - Bispebjerg and Frederiksberg,
4Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen,
5NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados