National Center for Natural Products Research,
School of Pharmacy,
Department of Pharmacology,
National Center for Natural Products Research, School of Pharmacy
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Time-resolved spectroscopic studies of B(12) coenzymes: a comparison of the primary photolysis mechanism in methyl-, ethyl-, n-propyl-, and 5'-deoxyadenosylcobalamin.
Journal of the American Chemical Society Jan, 2002 | Pubmed ID: 11792214
Natural products inhibiting Candida albicans secreted aspartic proteases from Tovomita krukovii.
Planta medica Jan, 2002 | Pubmed ID: 11842327
Biologically active secondary metabolites from Ginkgo biloba.
Journal of agricultural and food chemistry May, 2002 | Pubmed ID: 12009978
Antifungal activity of eupolauridine and its action on DNA topoisomerases.
Antimicrobial agents and chemotherapy Jun, 2002 | Pubmed ID: 12019091
New sesquiterpenoids from the root of Guatteria multivenia.
Journal of natural products Jun, 2002 | Pubmed ID: 12088427
Natural products inhibiting Candida albicans secreted aspartic proteases from Lycopodium cernuum.
Journal of natural products Jul, 2002 | Pubmed ID: 12141856
Characterization of Mycotypha metabolites found to be inhibitors of cell adhesion molecules.
The Journal of antibiotics Jun, 2002 | Pubmed ID: 12195965
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies.
Journal of natural products Dec, 2002 | Pubmed ID: 12502337
Flavanone glycosides from Miconia trailii.
Journal of natural products Jan, 2003 | Pubmed ID: 12542342
Cytotoxic sesquiterpene lactones from Centaurothamnus maximus and Vicoa pentanema.
Phytotherapy research : PTR Feb, 2003 | Pubmed ID: 12601682
Genipatriol, a new cycloartane triterpene from Genipa spruceana.
Journal of natural products Mar, 2003 | Pubmed ID: 12662099
Phenolic compounds from Nymphaea odorata.
Journal of natural products Apr, 2003 | Pubmed ID: 12713413
Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae.
The Journal of biological chemistry Sep, 2003 | Pubmed ID: 12824174
A new triterpene from Leandra chaetodon.
Planta medica Jun, 2003 | Pubmed ID: 12865988
Antiparasitic alkaloids from Psychotria klugii.
Journal of natural products Jul, 2003 | Pubmed ID: 12880315
Acetylenic acids inhibiting azole-resistant Candida albicans from Pentagonia gigantifolia.
Journal of natural products Aug, 2003 | Pubmed ID: 12932143
Cytotoxic and antioxidant activities of alkylated benzoquinones from Maesa lanceolata.
Phytotherapy research : PTR Sep, 2003 | Pubmed ID: 13680818
Reversal of fluconazole resistance in multidrug efflux-resistant fungi by the Dysidea arenaria sponge sterol 9alpha,11alpha-epoxycholest-7-ene-3beta,5alpha,6alpha,19-tetrol 6-acetate.
Journal of natural products Dec, 2003 | Pubmed ID: 14695809
Spectrophotometric determination of de novo hemozoin/beta-hematin formation in an in vitro assay.
Analytical biochemistry Feb, 2004 | Pubmed ID: 14715288
Transport of parthenolide across human intestinal cells (Caco-2).
Planta medica Nov, 2003 | Pubmed ID: 14735438
Circular dichroic properties of flavan-3,4-diols.
Journal of natural products Feb, 2004 | Pubmed ID: 14987054
Antimalarial and antileishmanial activities of aroyl-pyrrolyl-hydroxyamides, a new class of histone deacetylase inhibitors.
Antimicrobial agents and chemotherapy Apr, 2004 | Pubmed ID: 15047563
Synthesis and anticancer activities of fatty acid analogs of podophyllotoxin.
Lipids Feb, 2004 | Pubmed ID: 15134144
A new antimalarial quassinoid from Simaba orinocensis.
Journal of natural products May, 2004 | Pubmed ID: 15165136
Antifungal cyclopentenediones from Piper coruscans.
Journal of the American Chemical Society Jun, 2004 | Pubmed ID: 15174849
Piperazine-linked bisbenzamidines: a novel class of antileishmanial agents.
European journal of medicinal chemistry Jun, 2004 | Pubmed ID: 15183913
An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme.
European journal of biochemistry / FEBS Sep, 2004 | Pubmed ID: 15317584
Antimicrobial and antileishmanial activities of hypocrellins A and B.
Antimicrobial agents and chemotherapy Nov, 2004 | Pubmed ID: 15504880
Synthesis, spectroscopic, and biological studies of novel estolides derived from anticancer active 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate.
Lipids Jul, 2004 | Pubmed ID: 15588023
Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay.
Combinatorial chemistry & high throughput screening Feb, 2005 | Pubmed ID: 15720198
Natural products and antifungal drug discovery.
Methods in molecular medicine , 2005 | Pubmed ID: 15888937
Identification of bis-quindolines as new antiinfective agents.
Bioorganic & medicinal chemistry Jun, 2005 | Pubmed ID: 15911310
Anticancer activity and possible mode of action of 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate.
Lipids Mar, 2005 | Pubmed ID: 15957257
Synthesis and in vitro cytotoxic activity of N-, F-, and S-ether derivatives of podophyllotoxin fatty acid adducts.
Lipids Apr, 2005 | Pubmed ID: 16028720
Phenolic glycosides from Potalia amara.
Planta medica Oct, 2005 | Pubmed ID: 16254836
Antimycotic drug discovery in the age of genomics.
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice , 2005 | Pubmed ID: 16336002
8-Aminoquinolines: future role as antiprotozoal drugs.
Current opinion in infectious diseases Dec, 2006 | Pubmed ID: 17075340
Growth, drug susceptibility, and gene expression profiling of Plasmodium falciparum cultured in medium supplemented with human serum or lipid-rich bovine serum albumin [corrected].
Journal of biomolecular screening Dec, 2007 | Pubmed ID: 18087074
Role of heme in the antifungal activity of the azaoxoaporphine alkaloid sampangine.
Eukaryotic cell Feb, 2008 | Pubmed ID: 18156292
Transport of Schisandra chinensis extract and its biologically-active constituents across Caco-2 cell monolayers - an in-vitro model of intestinal transport.
The Journal of pharmacy and pharmacology Mar, 2008 | Pubmed ID: 18284817
Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate.
Antimicrobial agents and chemotherapy Jun, 2008 | Pubmed ID: 18378716
Antioxidant constituents of Nymphaea caerulea flowers.
Phytochemistry Jul, 2008 | Pubmed ID: 18534639
In vitro metabolic stability and intestinal transport of P57AS3 (P57) from Hoodia gordonii and its interaction with drug metabolizing enzymes.
Planta medica Aug, 2008 | Pubmed ID: 18612942
New labdane diterpenes from Leonurus cardiaca.
Planta medica Aug, 2008 | Pubmed ID: 18666048
Indolizidine, antiinfective and antiparasitic compounds from Prosopis glandulosa var. glandulosa.
Journal of natural products Jan, 2009 | Pubmed ID: 19105653
Alkaloids and saponins as cytochrome P450 inhibitors from blue cohosh (Caulophyllum thalictroides) in an in vitro assay.
Planta medica Mar, 2009 | Pubmed ID: 19137500
Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants.
Molecular and cellular biochemistry May, 2009 | Pubmed ID: 19184366
Bioactive (+)-manzamine A and (+)-8-hydroxymanzamine A tertiary bases and salts from Acanthostrongylophora ingens and their preparations.
Natural product communications Feb, 2009 | Pubmed ID: 19370920
Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.
Toxicology and applied pharmacology Nov, 2009 | Pubmed ID: 19616568
Antimicrobial, antiparasitic and cytotoxic spermine alkaloids from Albizia schimperiana.
Natural product communications Jun, 2009 | Pubmed ID: 19634324
Characterization of in vitro pharmacokinetic properties of hoodigogenin A from Hoodia gordonii.
Planta medica Jan, 2010 | Pubmed ID: 19639535
Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket.
Biochimie Nov-Dec, 2009 | Pubmed ID: 19772885
Cytochrome P450-dependent toxicity of dapsone in human erythrocytes.
Journal of applied toxicology : JAT Apr, 2010 | Pubmed ID: 19998329
Selective inhibition of human leukemia cell growth and induction of cell cycle arrest and apoptosis by pseudolaric acid B.
Journal of cancer research and clinical oncology Sep, 2010 | Pubmed ID: 20140742
Bioavailability, pharmacokinetics, and tissue distribution of the oxypregnane steroidal glycoside P57AS3 (P57) from Hoodia gordonii in mouse model.
Planta medica Oct, 2010 | Pubmed ID: 20414860
How physicians should evaluate dietary supplements.
The American journal of medicine Jul, 2010 | Pubmed ID: 20493463
Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum.
Natural product communications Jun, 2010 | Pubmed ID: 20614808
Analysis of primaquine and its metabolite carboxyprimaquine in biological samples: enantiomeric separation, method validation and quantification.
Biomedical chromatography : BMC Sep, 2011 | Pubmed ID: 21058417
Identification of 3-phenylaminoquinolinium and 3-phenylaminopyridinium salts as new agents against opportunistic fungal pathogens.
Bioorganic & medicinal chemistry Jan, 2011 | Pubmed ID: 21130660
Benzothieno[3,2-b]quinolinium and 3-(phenylthio)quinolinium compounds: Synthesis and evaluation against opportunistic fungal pathogens.
Bioorganic & medicinal chemistry Jan, 2011 | Pubmed ID: 21134759
Methemoglobinemia caused by 8-aminoquinoline drugs: DFT calculations suggest an analogy to H4B's role in nitric oxide synthase.
Journal of the American Chemical Society Feb, 2011 | Pubmed ID: 21244096
Oxidized low-density lipoprotein and tissue factor are involved in monocrotaline/lipopolysaccharide-induced hepatotoxicity.
Archives of toxicology Sep, 2011 | Pubmed ID: 21279329
The marine sponge-derived polyketide endoperoxide plakortide F acid mediates its antifungal activity by interfering with calcium homeostasis.
Antimicrobial agents and chemotherapy Apr, 2011 | Pubmed ID: 21300833
Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice.
Archives of toxicology Oct, 2011 | Pubmed ID: 21327618
Optimization of 3-(phenylthio)quinolinium compounds against opportunistic fungal pathogens.
European journal of medicinal chemistry May, 2011 | Pubmed ID: 21402432
Dietary supplements: safety issues and quality control.
Archives of internal medicine Mar, 2011 | Pubmed ID: 21403052
δ-Carbolines and their ring-opened analogs: synthesis and evaluation against fungal and bacterial opportunistic pathogens.
European journal of medicinal chemistry Jun, 2011 | Pubmed ID: 21459492
Tissue factor dependent liver injury causes release of retinoid receptors (RXR-α and RAR-α) as lipid droplets.
Biochemical and biophysical research communications Jun, 2011 | Pubmed ID: 21658367
Potential utility of natural products as regulators of breast cancer-associated aromatase promoters.
Reproductive biology and endocrinology : RB&E , 2011 | Pubmed ID: 21693041
DFT study on the radical anions formed by primaquine and its derivatives.
Chemical research in toxicology Sep, 2011 | Pubmed ID: 21699254
Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome.
Chemical research in toxicology Jan, 2012 | Pubmed ID: 21992498
Antiparasitic and antimicrobial isoflavanquinones from Abrus schimperi.
Natural product communications Nov, 2011 | Pubmed ID: 22224279
Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.
Bioorganic & medicinal chemistry letters Feb, 2012 | Pubmed ID: 22264472
Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway.
Toxicology Mar, 2012 | Pubmed ID: 22330256
Tissue factor antisense deoxyoligonucleotide prevents monocrotaline/LPS hepatotoxicity in mice.
Journal of applied toxicology : JAT Mar, 2012 | Pubmed ID: 22407844
CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.
Malaria journal , 2012 | Pubmed ID: 22856549
Pentacyclic ingamine alkaloids, a new antiplasmodial pharmacophore from the marine sponge Petrosid Ng5 Sp5.
Planta medica Oct, 2012 | Pubmed ID: 22903383
Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus.
Natural product communications Sep, 2012 | Pubmed ID: 23074885
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