Department of Biological Engineering
Peter C. Dedon has not added Biography.
If you are Peter C. Dedon and would like to personalize this page please email our Author Liaison for assistance.
Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal.
Proceedings of the National Academy of Sciences of the United States of America Sep, 1998 | Pubmed ID: 9736698
Absence of 2'-deoxyoxanosine and presence of abasic sites in DNA exposed to nitric oxide at controlled physiological concentrations.
Chemical research in toxicology Sep, 2003 | Pubmed ID: 12971791
Analysis of 3'-phosphoglycolaldehyde residues in oxidized DNA by gas chromatography/negative chemical ionization/mass spectrometry.
Chemical research in toxicology Dec, 2003 | Pubmed ID: 14680370
Reactive nitrogen species in the chemical biology of inflammation.
Archives of biochemistry and biophysics Mar, 2004 | Pubmed ID: 14989259
Reaction of 2'-deoxyribonucleosides with cis- and trans-1,4-dioxo-2-butene.
Biochemical and biophysical research communications Oct, 2004 | Pubmed ID: 15381076
5'-(2-phosphoryl-1,4-dioxobutane) as a product of 5'-oxidation of deoxyribose in DNA: elimination as trans-1,4-dioxo-2-butene and approaches to analysis.
Chemical research in toxicology Nov, 2004 | Pubmed ID: 15540938
Effects of peroxynitrite dose and dose rate on DNA damage and mutation in the supF shuttle vector.
Chemical research in toxicology Jan, 2005 | Pubmed ID: 15651852
Delineation of the chemical pathways underlying nitric oxide-induced homologous recombination in mammalian cells.
Chemistry & biology Mar, 2005 | Pubmed ID: 15797220
Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA.
The Journal of biological chemistry Jul, 2005 | Pubmed ID: 15878883
Differential oxidation of deoxyribose in DNA by gamma and alpha-particle radiation.
Radiation research Jun, 2005 | Pubmed ID: 15913397
Quantification of DNA strand breaks and abasic sites by oxime derivatization and accelerator mass spectrometry: application to gamma-radiation and peroxynitrite.
Analytical biochemistry Aug, 2005 | Pubmed ID: 15964542
Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species.
Mutation research Feb, 2006 | Pubmed ID: 16274707
Biological role of glutathione in nitric oxide-induced toxicity in cell culture and animal models.
Free radical biology & medicine Dec, 2005 | Pubmed ID: 16274884
Relatively small increases in the steady-state levels of nucleobase deamination products in DNA from human TK6 cells exposed to toxic levels of nitric oxide.
Chemical research in toxicology Jan, 2006 | Pubmed ID: 16411656
Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells.
Chemical research in toxicology Mar, 2006 | Pubmed ID: 16544944
Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammation.
Nature chemical biology Jul, 2006 | Pubmed ID: 16751762
Formation of 1,4-dioxo-2-butene-derived adducts of 2'-deoxyadenosine and 2'-deoxycytidine in oxidized DNA.
Chemical research in toxicology Aug, 2006 | Pubmed ID: 16918236
Rosuvastatin: an independent analysis of risks and benefits.
MedGenMed : Medscape general medicine Jun, 2006 | Pubmed ID: 16926812
The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA.
BMC genomics Dec, 2006 | Pubmed ID: 17163986
N-formylation of lysine in histone proteins as a secondary modification arising from oxidative DNA damage.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2007 | Pubmed ID: 17190813
Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation.
Carcinogenesis Aug, 2007 | Pubmed ID: 17347141
AlkB influences the chloroacetaldehyde-induced mutation spectra and toxicity in the pSP189 supF shuttle vector.
Chemical research in toxicology Aug, 2007 | Pubmed ID: 17658757
GC/MS methods to quantify the 2-deoxypentos-4-ulose and 3'-phosphoglycolate pathways of 4' oxidation of 2-deoxyribose in DNA: application to DNA damage produced by gamma radiation and bleomycin.
Chemical research in toxicology Nov, 2007 | Pubmed ID: 17944541
The chemical toxicology of 2-deoxyribose oxidation in DNA.
Chemical research in toxicology Jan, 2008 | Pubmed ID: 18052112
Oxidation of guanine in G, GG, and GGG sequence contexts by aromatic pyrenyl radical cations and carbonate radical anions: relationship between kinetics and distribution of alkali-labile lesions.
The journal of physical chemistry. B Feb, 2008 | Pubmed ID: 18211057
AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA.
Cancer research Jun, 2008 | Pubmed ID: 18519673
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice.
The Journal of clinical investigation Jul, 2008 | Pubmed ID: 18521188
Surveying the damage: the challenges of developing nucleic acid biomarkers of inflammation.
Molecular bioSystems Sep, 2008 | Pubmed ID: 18704228
Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandem mass spectrometry.
Nature protocols , 2008 | Pubmed ID: 18714297
Kinetic analysis of intracellular concentrations of reactive nitrogen species.
Chemical research in toxicology Nov, 2008 | Pubmed ID: 18828639
DNA sequence context as a determinant of the quantity and chemistry of guanine oxidation produced by hydroxyl radicals and one-electron oxidants.
The Journal of biological chemistry Dec, 2008 | Pubmed ID: 18948263
Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2009 | Pubmed ID: 19118192
An improved method for large-scale preparation of negatively and positively supercoiled plasmid DNA.
BioTechniques Jul, 2009 | Pubmed ID: 19594448
A general method for quantifying sequence effects on nucleobase oxidation in DNA.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20013187
Recommendations for standardized description of and nomenclature concerning oxidatively damaged nucleobases in DNA.
Chemical research in toxicology Apr, 2010 | Pubmed ID: 20235554
Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.
Molecular and cellular biology May, 2010 | Pubmed ID: 20308323
Quantification of the 2-deoxyribonolactone and nucleoside 5'-aldehyde products of 2-deoxyribose oxidation in DNA and cells by isotope-dilution gas chromatography mass spectrometry: differential effects of gamma-radiation and Fe2+-EDTA.
Journal of the American Chemical Society May, 2010 | Pubmed ID: 20377226
One-electron oxidation of a pyrenyl photosensitizer covalently attached to DNA and competition between its further oxidation and DNA hole injection.
Photochemistry and photobiology , 2010 | Pubmed ID: 20408978
Challenges in developing DNA and RNA biomarkers of inflammation.
Biomarkers in medicine Aug, 2007 | Pubmed ID: 20477404
A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress.
PLoS genetics Dec, 2010 | Pubmed ID: 21187895
The biological and metabolic fates of endogenous DNA damage products.
Journal of nucleic acids Dec, 2010 | Pubmed ID: 21209721
DNA phosphorothioation is widespread and quantized in bacterial genomes.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2011 | Pubmed ID: 21285367
Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates.
International journal of cancer May, 2011 | Pubmed ID: 21387284
Solvent exposure associated with single abasic sites alters the base sequence dependence of oxidation of guanine in DNA in GG sequence contexts.
Chembiochem : a European journal of chemical biology Jul, 2011 | Pubmed ID: 21656632
Identification of N6,N6-dimethyladenosine in transfer RNA from Mycobacterium bovis Bacille Calmette-Guérin.
Molecules (Basel, Switzerland) Jun, 2011 | Pubmed ID: 21694680
XRCC1 and base excision repair balance in response to nitric oxide.
DNA repair Dec, 2011 | Pubmed ID: 22041025
Sequence-dependent variation in the reactivity of 8-Oxo-7,8-dihydro-2'-deoxyguanosine toward oxidation.
Chemical research in toxicology Feb, 2012 | Pubmed ID: 22103813
Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids.
Free radical research Apr, 2012 | Pubmed ID: 22263561
Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2012 | Pubmed ID: 22308425
2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase.
PLoS pathogens , 2012 | Pubmed ID: 22496660
Integrated molecular analysis indicates undetectable change in DNA damage in mice after continuous irradiation at ~ 400-fold natural background radiation.
Environmental health perspectives Aug, 2012 | Pubmed ID: 22538203
Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2012 | Pubmed ID: 22689960
A system for exposing molecules and cells to biologically relevant and accurately controlled steady-state concentrations of nitric oxide and oxygen.
Nitric oxide : biology and chemistry Oct, 2012 | Pubmed ID: 22728703
Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins.
Nature communications Jul, 2012 | Pubmed ID: 22760636
Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications.
RNA biology Jul, 2012 | Pubmed ID: 22832247
Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response.
Cell cycle (Georgetown, Tex.) Oct, 2012 | Pubmed ID: 22935709
In situ analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine oxidation reveals sequence- and agent-specific damage spectra.
Journal of the American Chemical Society Oct, 2012 | Pubmed ID: 23057664
Comparative analysis of four oxidized guanine lesions from reactions of DNA with peroxynitrite, singlet oxygen, and γ-radiation.
Chemical research in toxicology Feb, 2013 | Pubmed ID: 23140136
Quantitative analysis of histone modifications: formaldehyde is a source of pathological n(6)-formyllysine that is refractory to histone deacetylases.
PLoS genetics , 2013 | Pubmed ID: 23468656
Increased levels of inosine in a mouse model of inflammation.
Chemical research in toxicology Apr, 2013 | Pubmed ID: 23506120
Quantification of cellular poly(ADP-ribosyl)ation by stable isotope dilution mass spectrometry reveals tissue- and drug-dependent stress response dynamics.
ACS chemical biology Jul, 2013 | Pubmed ID: 23631432
An automated Fpg-based FADU method for the detection of oxidative DNA lesions and screening of antioxidants.
Toxicology Aug, 2013 | Pubmed ID: 23707620
Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2013 | Pubmed ID: 23754421
DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis.
PLoS pathogens , 2013 | Pubmed ID: 23853579
A multidimensional platform for the purification of non-coding RNA species.
Nucleic acids research Sep, 2013 | Pubmed ID: 23907385
Chemistry meets biology in colitis-associated carcinogenesis.
Free radical research Nov, 2013 | Pubmed ID: 23926919
Induction of functional human macrophages from bone marrow promonocytes by M-CSF in humanized mice.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2013 | Pubmed ID: 23935193
Dosimetry of N⁶-formyllysine adducts following [¹³C²H₂]-formaldehyde exposures in rats.
Chemical research in toxicology Oct, 2013 | Pubmed ID: 24087891
Identification and codon reading properties of 5-cyanomethyl uridine, a new modified nucleoside found in the anticodon wobble position of mutant haloarchaeal isoleucine tRNAs.
RNA (New York, N.Y.) Feb, 2014 | Pubmed ID: 24344322
A system of RNA modifications and biased codon use controls cellular stress response at the level of translation.
Chemical research in toxicology Mar, 2014 | Pubmed ID: 24422464
28S rRNA is inducibly pseudouridylated by the mTOR pathway translational control in CHO cell cultures.
Journal of biotechnology Mar, 2014 | Pubmed ID: 24480570
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry.
Nature protocols Apr, 2014 | Pubmed ID: 24625781
Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences.
Nature communications Jun, 2014 | Pubmed ID: 24899568
Pathological phenotypes and in vivo DNA cleavage by unrestrained activity of a phosphorothioate-based restriction system in Salmonella.
Molecular microbiology Aug, 2014 | Pubmed ID: 25040300
tRNA modifications regulate translation during cellular stress.
FEBS letters Nov, 2014 | Pubmed ID: 25304425
Diverse cell stresses induce unique patterns of tRNA up- and down-regulation: tRNA-seq for quantifying changes in tRNA copy number.
Nucleic acids research Dec, 2014 | Pubmed ID: 25348403
Mycobacterial RNA isolation optimized for non-coding RNA: high fidelity isolation of 5S rRNA from Mycobacterium bovis BCG reveals novel post-transcriptional processing and a complete spectrum of modified ribonucleosides.
Nucleic acids research Mar, 2015 | Pubmed ID: 25539917
Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes.
Chemical research in toxicology May, 2015 | Pubmed ID: 25772370
Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses.
RNA biology , 2015 | Pubmed ID: 25892531
Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage.
PloS one , 2015 | Pubmed ID: 26147969
A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications.
Methods in enzymology , 2015 | Pubmed ID: 26253965
Metabolic fate of endogenous molecular damage: Urinary glutathione conjugates of DNA-derived base propenals as markers of inflammation.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2015 | Pubmed ID: 26283391
An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis.
RNA (New York, N.Y.) Dec, 2015 | Pubmed ID: 26516084
Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation.
PLoS genetics Dec, 2015 | Pubmed ID: 26670883
Novel genomic island modifies DNA with 7-deazaguanine derivatives.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2016 | Pubmed ID: 26929322
Immunostimulating and Gram-negative-specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea).
The FEBS journal Jun, 2016 | Pubmed ID: 27007913
Gene- and genome-based analysis of significant codon patterns in yeast, rat and mice genomes with the CUT Codon UTilization tool.
Methods (San Diego, Calif.) Sep, 2016 | Pubmed ID: 27245397
The role of sequence context, nucleotide pool balance and stress in 2'-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA.
Nucleic acids research Oct, 2016 | Pubmed ID: 27365049
Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa.
Nucleic acids research Dec, 2016 | Pubmed ID: 27683218
tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence.
Nature communications Nov, 2016 | Pubmed ID: 27834374
tRNA N6-adenosine threonylcarbamoyltransferase defect due to KAE1/TCS3 (OSGEP) mutation manifest by neurodegeneration and renal tubulopathy.
European journal of human genetics : EJHG May, 2017 | Pubmed ID: 28272532
Production of Superoxide in Bacteria Is Stress- and Cell State-Dependent: A Gating-Optimized Flow Cytometry Method that Minimizes ROS Measurement Artifacts with Fluorescent Dyes.
Frontiers in microbiology , 2017 | Pubmed ID: 28377755
Convergence of DNA methylation and phosphorothioation epigenetics in bacterial genomes.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2017 | Pubmed ID: 28400512
Oxidation of phosphorothioate DNA modifications leads to lethal genomic instability.
Nature chemical biology Aug, 2017 | Pubmed ID: 28604692
Three distinct 3-methylcytidine (mC) methyltransferases modify tRNA and mRNA in mice and humans.
The Journal of biological chemistry 09, 2017 | Pubmed ID: 28655767
The mA pathway facilitates sex determination in Drosophila.
Nature communications Jul, 2017 | Pubmed ID: 28675155
N-Formyllysine as a Biomarker of Formaldehyde Exposure: Formation and Loss of N-Formyllysine in Nasal Epithelium in Long-Term, Low-Dose Inhalation Studies in Rats.
Chemical research in toxicology Aug, 2017 | Pubmed ID: 28692800
The tA modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans.
RNA biology , 2018 | Pubmed ID: 28726545
Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.
Nature genetics Oct, 2017 | Pubmed ID: 28805828
Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis.
Nature communications Dec, 2017 | Pubmed ID: 29215013
Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network.
Journal of immunology (Baltimore, Md. : 1950) May, 2018 | Pubmed ID: 29610140
Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression.
Science advances Jul, 2018 | Pubmed ID: 30009260
Identification of the minimal bacterial 2'-deoxy-7-amido-7-deazaguanine synthesis machinery.
Molecular microbiology Nov, 2018 | Pubmed ID: 30159947
Aristolochic Acids as Persistent Soil Pollutants: Determination of Risk for Human Exposure and Nephropathy from Plant Uptake.
Journal of agricultural and food chemistry Oct, 2018 | Pubmed ID: 30286603
tRNA epitranscriptomics and biased codon are linked to proteome expression in .
Molecular systems biology Oct, 2018 | Pubmed ID: 30287681
DNA phosphorothioate modification-a new multi-functional epigenetic system in bacteria.
FEMS microbiology reviews Mar, 2019 | Pubmed ID: 30289455
Backbone resonance assignment for the N-terminal region of bacterial tRNA-(NG37) methyltransferase.
Biomolecular NMR assignments Apr, 2019 | Pubmed ID: 30298375
A Proteomics Approach to Profiling the Temporal Translational Response to Stress and Growth.
iScience Nov, 2018 | Pubmed ID: 30466063
Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses.
Genome biology Dec, 2018 | Pubmed ID: 30587213
The Versatile Roles of the tRNA Epitranscriptome during Cellular Responses to Toxic Exposures and Environmental Stress.
Toxics Mar, 2019 | Pubmed ID: 30934574
Backbone resonance assignment for the full length tRNA-(NG37) methyltransferase of Pseudomonas aeruginosa.
Biomolecular NMR assignments Oct, 2019 | Pubmed ID: 31175551
The road less traveled: A new phosphorothioate antiviral defense mechanism discovered in Archaea.
Synthetic and systems biotechnology Sep, 2019 | Pubmed ID: 31312729
Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis.
Journal of molecular biology Sep, 2019 | Pubmed ID: 31381898
Transcriptome-wide dynamics of extensive mA mRNA methylation during Plasmodium falciparum blood-stage development.
Nature microbiology Dec, 2019 | Pubmed ID: 31384004
Crystal structure and catalytic mechanism of the essential mG37 tRNA methyltransferase TrmD from .
RNA (New York, N.Y.) Nov, 2019 | Pubmed ID: 31399541
Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
Journal of medicinal chemistry Sep, 2019 | Pubmed ID: 31442049
Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2019 | Pubmed ID: 31481610
Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA.
Nucleic acids research Nov, 2019 | Pubmed ID: 31504804
Discovery of a new predominant cytosine DNA modification that is linked to gene expression in malaria parasites.
Nucleic acids research Jan, 2020 | Pubmed ID: 31777939
7-Deazaguanine modifications protect phage DNA from host restriction systems.
Nature communications Nov, 2019 | Pubmed ID: 31784519
Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.
Nature communications Jan, 2020 | Pubmed ID: 31941883
Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast.
Biomolecules Feb, 2020 | Pubmed ID: 32085421
SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities.
Nature microbiology Jul, 2020 | Pubmed ID: 32251370
The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene.
Epigenetics Oct, 2020 | Pubmed ID: 32303148
Nick-seq for single-nucleotide resolution genomic maps of DNA modifications and damage.
Nucleic acids research Jul, 2020 | Pubmed ID: 32484547
Epigenetic competition reveals density-dependent regulation and target site plasticity of phosphorothioate epigenetics in bacteria.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2020 | Pubmed ID: 32518115
DNA Phosphorothioate Modifications Are Widely Distributed in the Human Microbiome.
Biomolecules Aug, 2020 | Pubmed ID: 32806589
Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite.
Molecular systems biology Aug, 2020 | Pubmed ID: 32816370
Pyruvate kinase from Plasmodium falciparum: Structural and kinetic insights into the allosteric mechanism.
Biochemical and biophysical research communications Nov, 2020 | Pubmed ID: 32878705
Crystal structure of the periplasmic sensor domain of histidine kinase VbrK suggests indirect sensing of β-lactam antibiotics.
Journal of structural biology Nov, 2020 | Pubmed ID: 32890780
tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast.
RNA biology Apr, 2021 | Pubmed ID: 32893724
Detection of preQ0 deazaguanine modifications in bacteriophage CAjan DNA using Nanopore sequencing reveals same hypermodification at two distinct DNA motifs.
Nucleic acids research Oct, 2020 | Pubmed ID: 32941607
Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens.
Cell systems Sep, 2020 | Pubmed ID: 32970993
Development of Methods Derived from Iodine-Induced Specific Cleavage for Identification and Quantitation of DNA Phosphorothioate Modifications.
Biomolecules Oct, 2020 | Pubmed ID: 33126637
Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator.
mBio Mar, 2021 | Pubmed ID: 33688012
Quantitative mapping of the cellular small RNA landscape with AQRNA-seq.
Nature biotechnology Aug, 2021 | Pubmed ID: 33859402
Functional Characterization of the mA-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite.
mBio Apr, 2021 | Pubmed ID: 33906926
Detecting the epitranscriptome.
Wiley interdisciplinary reviews. RNA Nov, 2021 | Pubmed ID: 33987958
Bacteriophage vB_PagS_MED16-A Siphovirus Containing a 2'-Deoxy-7-amido-7-deazaguanosine-Modified DNA.
International journal of molecular sciences Jul, 2021 | Pubmed ID: 34298953
Strategies to Avoid Artifacts in Mass Spectrometry-Based Epitranscriptome Analyses.
Angewandte Chemie (International ed. in English) Oct, 2021 | Pubmed ID: 34339593
Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site.
The Journal of biological chemistry Feb, 2022 | Pubmed ID: 35007529
Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences.
Frontiers in microbiology , 2022 | Pubmed ID: 35531280
Queuine Salvaging in the Human Parasite .
Cells Aug, 2022 | Pubmed ID: 36010587
The absence of the queuosine tRNA modification leads to pleiotropic phenotypes revealing perturbations of metal and oxidative stress homeostasis in Escherichia coli K12.
Metallomics : integrated biometal science Sep, 2022 | Pubmed ID: 36066904
Arsenite toxicity is regulated by queuine availability and oxidation-induced reprogramming of the human tRNA epitranscriptome.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2022 | Pubmed ID: 36095201
Dysfunctional tRNA reprogramming and codon-biased translation in cancer.
Trends in molecular medicine Nov, 2022 | Pubmed ID: 36241532
DNA Modifications Enabling Proximity Biotinylation.
Bioconjugate chemistry Mar, 2023 | Pubmed ID: 36888923
Accumulation of mA exhibits stronger correlation with MAPT than β-amyloid pathology in an APP /MAPT mouse model of Alzheimer's disease.
bioRxiv : the preprint server for biology Mar, 2023 | Pubmed ID: 37034774
Rifaximin potentiates clarithromycin against and in zebrafish.
JAC-antimicrobial resistance Jun, 2023 | Pubmed ID: 37168836
Accumulation of mA exhibits stronger correlation with MAPT than β-amyloid pathology in an APP /MAPT mouse model of Alzheimer's disease.
Research square May, 2023 | Pubmed ID: 37292629
An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis.
Nature communications Jul, 2023 | Pubmed ID: 37433804
A systems-level mass spectrometry-based technique for accurate and sensitive quantification of the RNA cap epitranscriptome.
Nature protocols Sep, 2023 | Pubmed ID: 37567932
Four additional natural 7-deazaguanine derivatives in phages and how to make them.
Nucleic acids research Sep, 2023 | Pubmed ID: 37572349
Cohesin contributes to transcriptional repression of stage-specific genes in the human malaria parasite.
EMBO reports Oct, 2023 | Pubmed ID: 37592911
Nanopore-based direct sequencing of RNA transcripts with 10 different modified nucleotides reveals gaps in existing technology.
G3 (Bethesda, Md.) Nov, 2023 | Pubmed ID: 37655917
Discovery adductomics provides a comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans.
Nucleic acids research Nov, 2023 | Pubmed ID: 37843128
Dengue virus exploits the host tRNA epitranscriptome to promote viral replication.
bioRxiv : the preprint server for biology Nov, 2023 | Pubmed ID: 37986976
Molecular Coping Mechanisms: Reprogramming tRNAs To Regulate Codon-Biased Translation of Stress Response Proteins.
Accounts of chemical research Dec, 2023 | Pubmed ID: 37992267
The Greatwall-Endosulfine-PP2A/B55 pathway controls entry into quiescence by promoting translation of Elongator-tuneable transcripts.
Research square Dec, 2023 | Pubmed ID: 38105947
Queuosine Salvage in Houston 1: A Unique Evolutionary Path.
bioRxiv : the preprint server for biology Dec, 2023 | Pubmed ID: 38106016
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados