Biozentrum
Dirk Bumann has not added Biography.
If you are Dirk Bumann and would like to personalize this page please email our Author Liaison for assistance.
Has nature already identified all useful antibacterial targets?
Current opinion in microbiology Oct, 2008 | Pubmed ID: 18804175
System-level analysis of Salmonella metabolism during infection.
Current opinion in microbiology Oct, 2009 | Pubmed ID: 19744878
Pathogen proteomes during infection: A basis for infection research and novel control strategies.
Journal of proteomics Oct, 2010 | Pubmed ID: 20797457
A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2.
BMC systems biology , 2011 | Pubmed ID: 21244678
Salmonella-induced mucosal lectin RegIIIβ kills competing gut microbiota.
PloS one , 2011 | Pubmed ID: 21694778
Identification of tumor-specific Salmonella Typhimurium promoters and their regulatory logic.
Nucleic acids research Apr, 2012 | Pubmed ID: 22140114
Intestinal inflammation responds to microbial tissue load independent of pathogen/non-pathogen discrimination.
PloS one , 2012 | Pubmed ID: 22586458
Extensive in vivo resilience of persistent Salmonella.
PloS one , 2012 | Pubmed ID: 22911873
Immunity to intracellular Salmonella depends on surface-associated antigens.
PLoS pathogens , 2012 | Pubmed ID: 23093937
Functional identification of APIP as human mtnB, a key enzyme in the methionine salvage pathway.
PloS one , 2012 | Pubmed ID: 23285211
Parallel exploitation of diverse host nutrients enhances Salmonella virulence.
PLoS pathogens , 2013 | Pubmed ID: 23633950
Disparate impact of oxidative host defenses determines the fate of Salmonella during systemic infection in mice.
Cell host & microbe Jan, 2014 | Pubmed ID: 24439899
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.
Nature May, 2014 | Pubmed ID: 24739961
The central metabolism regulator EIIAGlc switches Salmonella from growth arrest to acute virulence through activation of virulence factor secretion.
Cell reports Jun, 2014 | Pubmed ID: 24835993
Shigella reroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2014 | Pubmed ID: 24958876
Phenotypic variation of Salmonella in host tissues delays eradication by antimicrobial chemotherapy.
Cell Aug, 2014 | Pubmed ID: 25126781
Identification of Protective Antigens for Vaccination against Systemic Salmonellosis.
Frontiers in immunology , 2014 | Pubmed ID: 25157252
Fast sampling method for mammalian cell metabolic analyses using liquid chromatography-mass spectrometry.
Nature protocols Jan, 2015 | Pubmed ID: 25474028
PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.
Cell host & microbe Jan, 2015 | Pubmed ID: 25500191
Heterogeneous host-pathogen encounters: act locally, think globally.
Cell host & microbe Jan, 2015 | Pubmed ID: 25590757
Catechol siderophores repress the pyochelin pathway and activate the enterobactin pathway in Pseudomonas aeruginosa: an opportunity for siderophore-antibiotic conjugates development.
Environmental microbiology Mar, 2016 | Pubmed ID: 26718479
Combining Shigella Tn-seq data with gold-standard E. coli gene deletion data suggests rare transitions between essential and non-essential gene functionality.
BMC microbiology Sep, 2016 | Pubmed ID: 27599549
A Novel Genome-Editing Platform for Drug-Resistant Acinetobacter baumannii Reveals an AdeR-Unrelated Tigecycline Resistance Mechanism.
Antimicrobial agents and chemotherapy Dec, 2016 | Pubmed ID: 27671072
Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage.
Nature microbiology Jan, 2017 | Pubmed ID: 28112722
Intracellular Salmonella metabolism.
Cellular microbiology Oct, 2017 | Pubmed ID: 28672057
Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling.
Infection and immunity Dec, 2017 | Pubmed ID: 28874447
Heterogeneity of Salmonella-host interactions in infected host tissues.
Current opinion in microbiology Oct, 2017 | Pubmed ID: 28988065
Structural basis for maintenance of bacterial outer membrane lipid asymmetry.
Nature microbiology Dec, 2017 | Pubmed ID: 29038444
Editorial overview: Bacterial systems biology.
Current opinion in microbiology Oct, 2017 | Pubmed ID: 29241558
Correction for Wu et al., "Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages via Modulation of NF-κB Signaling".
Infection and immunity Mar, 2018 | Pubmed ID: 29463686
TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates.
Antimicrobial agents and chemotherapy Jun, 2018 | Pubmed ID: 29555629
The hepcidin-ferroportin axis controls the iron content of Salmonella-containing vacuoles in macrophages.
Nature communications May, 2018 | Pubmed ID: 29844422
Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.
Nature immunology Jul, 2018 | Pubmed ID: 29925993
Getting Drugs through Small Pores: Exploiting the Porins Pathway in Pseudomonas aeruginosa.
ACS infectious diseases Oct, 2018 | Pubmed ID: 30039960
A Multidisciplinary Approach toward Identification of Antibiotic Scaffolds for Acinetobacter baumannii.
Structure (London, England : 1993) Feb, 2019 | Pubmed ID: 30554842
Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity.
Immunity Jan, 2019 | Pubmed ID: 30611611
Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains.
EBioMedicine Mar, 2019 | Pubmed ID: 30852163
Publisher Correction: Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.
Nature immunology Apr, 2019 | Pubmed ID: 30862955
Single-Cell Metabolism and Stress Responses in Complex Host Tissues.
Microbiology spectrum Mar, 2019 | Pubmed ID: 30953427
Definitions and guidelines for research on antibiotic persistence.
Nature reviews. Microbiology Jul, 2019 | Pubmed ID: 30980069
Publisher Correction: Definitions and guidelines for research on antibiotic persistence.
Nature reviews. Microbiology Jul, 2019 | Pubmed ID: 31036919
Dissecting Colistin Resistance Mechanisms in Extensively Drug-Resistant Acinetobacter baumannii Clinical Isolates.
mBio Jul, 2019 | Pubmed ID: 31311879
Non-specific interference of cobalt with siderophore-dependent iron uptake pathways.
Metallomics : integrated biometal science Nov, 2019 | Pubmed ID: 31633703
Antibiotic chemotherapy against heterogeneous pathogen populations in complex host tissues.
F1000Research , 2019 | Pubmed ID: 31737252
Host resistance factor SLC11A1 restricts growth through magnesium deprivation.
Science (New York, N.Y.) Nov, 2019 | Pubmed ID: 31753999
Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression.
Mucosal immunology May, 2020 | Pubmed ID: 31953493
Classical Activation of Macrophages Leads to Lipid Droplet Formation Without Fatty Acid Synthesis.
Frontiers in immunology , 2020 | Pubmed ID: 32132994
Efficient dual-negative selection for bacterial genome editing.
BMC microbiology May, 2020 | Pubmed ID: 32448155
Dynamics in protein translation sustaining T cell preparedness.
Nature immunology Aug, 2020 | Pubmed ID: 32632289
Single-cell reporters for pathogen responses to antimicrobial host attacks.
Current opinion in microbiology Feb, 2021 | Pubmed ID: 32810800
Regulation of chaperone function by coupled folding and oligomerization.
Science advances Oct, 2020 | Pubmed ID: 33087350
Molecular reprogramming and phenotype switching in lead to high antibiotic persistence and affect therapy success.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2021 | Pubmed ID: 33574060
Increased Production of Outer Membrane Vesicles by Salmonella Interferes with Complement-Mediated Innate Immune Attack.
mBio Jun, 2021 | Pubmed ID: 34061589
Ferritin H deficiency deteriorates cellular iron handling and worsens Salmonella typhimurium infection by triggering hyperinflammation.
JCI insight Jul, 2021 | Pubmed ID: 34236052
Outer membrane permeability: Antimicrobials and diverse nutrients bypass porins in .
Proceedings of the National Academy of Sciences of the United States of America Aug, 2021 | Pubmed ID: 34326266
Acquisition of ionic copper by the bacterial outer membrane protein OprC through a novel binding site.
PLoS biology Nov, 2021 | Pubmed ID: 34762655
Tissue compartmentalization enables persistence during chemotherapy.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2021 | Pubmed ID: 34911764
Making Antimicrobial Susceptibility Testing More Physiologically Relevant with Bicarbonate?
Antimicrobial agents and chemotherapy May, 2022 | Pubmed ID: 35435706
Plant-Derived Catechols Are Substrates of TonB-Dependent Transporters and Sensitize Pseudomonas aeruginosa to Siderophore-Drug Conjugates.
mBio Aug, 2022 | Pubmed ID: 35770947
Importance of aspartyl protease 5 in the establishment of the intracellular niche during acute and chronic infection of Toxoplasma gondii.
Molecular microbiology Dec, 2022 | Pubmed ID: 36210525
Zebrafish Larvae as an Model for Antimicrobial Activity Tests against Intracellular .
Frontiers in bioscience (Landmark edition) May, 2023 | Pubmed ID: 37258480
Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions.
Nature microbiology Jan, 2024 | Pubmed ID: 38177300
SOBRE A JoVE
Copyright © 2024 MyJoVE Corporation. Todos os direitos reservados