Cristian Coarfa

Department of Molecular and Cellular Biology, Baylor College of Medicine

Affiliated withBaylor College of Medicine

Research Area

Biology

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2024

Other Publications

Article	Year
Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis. Cancer cell\| PubMed ID: 27889186	2016
Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression. Autophagy\| PubMed ID: 27977328	2017
REST represses miR-124 and miR-203 to regulate distinct oncogenic properties of glioblastoma stem cells. Neuro-oncology\| PubMed ID: 28040710	2017
Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells. Leukemia\| PubMed ID: 28042144	2017
Regulation of miRNA-29c and its downstream pathways in preneoplastic progression of triple-negative breast cancer. Oncotarget\| PubMed ID: 28160548	2017
Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome. Scientific reports\| PubMed ID: 28377578	2017
SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein. Oncogene\| PubMed ID: 28414305	2017
Elevated TATA-binding protein expression drives vascular endothelial growth factor expression in colon cancer. Oncotarget\| PubMed ID: 28415573	2017
Glutamine Transporters Are Targets of Multiple Oncogenic Signaling Pathways in Prostate Cancer. Molecular cancer research : MCR\| PubMed ID: 28507054	2017
Vitamin D receptor activation reduces VCaP xenograft tumor growth and counteracts ERG activity despite induction of TMPRSS2:ERG. Oncotarget\| PubMed ID: 28591703	2017
Peroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse. PLoS genetics\| PubMed ID: 28640802	2017
miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma. International journal of cancer\| PubMed ID: 28748534	2017
Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder. European urology focus\| PubMed ID: 28753886	2018
Sexual dimorphism of the pulmonary transcriptome in neonatal hyperoxic lung injury: identification of angiogenesis as a key pathway. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 28818871	2017
Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 28851690	2017
Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy. JCI insight\| PubMed ID: 28878117	2017
A new mild hyperthermia device to treat vascular involvement in cancer surgery. Scientific reports\| PubMed ID: 28900126	2017
Pharmacological inhibition of CaMKK2 with the selective antagonist STO-609 regresses NAFLD. Scientific reports\| PubMed ID: 28924233	2017
Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells. Cell discovery\| PubMed ID: 28955502	2017
Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs. Cell reports\| PubMed ID: 29117561	2017
Distinct TP63 Isoform-Driven Transcriptional Signatures Predict Tumor Progression and Clinical Outcomes. Cancer research\| PubMed ID: 29180475	2018
EWS-FLI1 and RNA helicase A interaction inhibitor YK-4-279 inhibits growth of neuroblastoma. Oncotarget\| PubMed ID: 29212266	2017
Expression of ganglioside GD2, reprogram the lipid metabolism and EMT phenotype in bladder cancer. Oncotarget\| PubMed ID: 29221154	2017
Unique metabolomic signature associated with hepatorenal dysfunction and mortality in cirrhosis. Translational research : the journal of laboratory and clinical medicine\| PubMed ID: 29291380	2018
Epigenetic supersimilarity of monozygotic twin pairs. Genome biology\| PubMed ID: 29310692	2018
Suppression of Activated FOXO Transcription Factors in the Heart Prolongs Survival in a Mouse Model of Laminopathies. Circulation research\| PubMed ID: 29317431	2018
ICG-001 Exerts Potent Anticancer Activity Against Uveal Melanoma Cells. Investigative ophthalmology & visual science\| PubMed ID: 29332125	2018
GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling. Endocrine-related cancer\| PubMed ID: 29431615	2018
An integrative transcriptomic approach to identify depot differences in genes and microRNAs in adipose tissues from high fat fed mice. Oncotarget\| PubMed ID: 29507687	2018
The NIEHS TaRGET II Consortium and environmental epigenomics. Nature biotechnology\| PubMed ID: 29509741	2018
Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature\| PubMed ID: 29615789	2018
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell reports\| PubMed ID: 29617660	2018
Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 29752313	2018
MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma. Oncotarget\| PubMed ID: 29755654	2018
Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1. Human molecular genetics\| PubMed ID: 29771332	2018
Expression of Long Noncoding RNA Promotes Glycolysis in Breast Cancer. Cancer research\| PubMed ID: 29967256	2018
miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity. Diabetes\| PubMed ID: 30002134	2018
Unbiased Lipidomic Profiling of Triple-Negative Breast Cancer Tissues Reveals the Association of Sphingomyelin Levels with Patient Disease-Free Survival. Metabolites\| PubMed ID: 30011843	2018
Correction: MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma. Oncotarget\| PubMed ID: 30042831	2018
APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa. Science translational medicine\| PubMed ID: 30135250	2018
Allele-specific epigenome maps reveal sequence-dependent stochastic switching at regulatory loci. Science (New York, N.Y.)\| PubMed ID: 30139913	2018
Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. Scientific reports\| PubMed ID: 30177747	2018
Inositol polyphosphate 4-phosphatase type II regulation of androgen receptor activity. Oncogene\| PubMed ID: 30228349	2019
TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy. Oncoimmunology\| PubMed ID: 30288358	2018
The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast. Journal of mammary gland biology and neoplasia\| PubMed ID: 30338425	2018
MicroRNA-30a as a candidate underlying sex-specific differences in neonatal hyperoxic lung injury: implications for BPD. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 30382766	2019
Beyond Autoantibodies: Biologic Roles of Human Autoreactive B Cells in Rheumatoid Arthritis Revealed by RNA-Sequencing. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 30407753	2019
Correction to: The Emerging Roles of Steroid Hormone Receptors in Ductal Carcinoma in Situ (DCIS) of the Breast. Journal of mammary gland biology and neoplasia\| PubMed ID: 30465315	2019
The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Science translational medicine\| PubMed ID: 30545964	2018
Targeting nuclear β-catenin as therapy for post-myeloproliferative neoplasm secondary AML. Leukemia\| PubMed ID: 30575820	2019
Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. Cell\| PubMed ID: 30633903	2019
Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells. Blood cancer journal\| PubMed ID: 30647404	2019
Plasma Urea Cycle Metabolites May Be Useful Biomarkers in Children With Eosinophilic Esophagitis. Frontiers in pediatrics\| PubMed ID: 30687688	2018
DNA Damage Response/TP53 Pathway Is Activated and Contributes to the Pathogenesis of Dilated Cardiomyopathy Associated With LMNA (Lamin A/C) Mutations. Circulation research\| PubMed ID: 30696354	2019
A Prospective Targeted Serum Metabolomics Study of Pancreatic Cancer in Postmenopausal Women. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 30723176	2019
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes Is Associated With Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy. Circulation research\| PubMed ID: 30739589	2019
Tegavivint and the β-Catenin/ALDH Axis in Chemotherapy-Resistant and Metastatic Osteosarcoma. Journal of the National Cancer Institute\| PubMed ID: 30793158	2019
Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 30846479	2019
REST-DRD2 mechanism impacts glioblastoma stem cell-mediated tumorigenesis. Neuro-oncology\| PubMed ID: 30953587	2019
Activating p53 family member TAp63: A novel therapeutic strategy for targeting p53-altered tumors. Cancer\| PubMed ID: 31012964	2019
RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1. Blood\| PubMed ID: 31023702	2019
Transcriptomic profiling identifies novel mechanisms of transcriptional regulation of the cytochrome P450 (Cyp)3a11 gene. Scientific reports\| PubMed ID: 31040347	2019
Cigarette smoke-induced reduction of C1q promotes emphysema. JCI insight\| PubMed ID: 31112138	2019
A genomic atlas of systemic interindividual epigenetic variation in humans. Genome biology\| PubMed ID: 31155008	2019
Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression. Nature immunology\| PubMed ID: 31160797	2019
Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer. Nature metabolism\| PubMed ID: 31198906	2019
CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†. Biology of reproduction\| PubMed ID: 31201419	2019
Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB). Biochemical and biophysical research communications\| PubMed ID: 31208719	2019
Short-term RANKL exposure initiates a neoplastic transcriptional program in the basal epithelium of the murine salivary gland. Cytokine\| PubMed ID: 31226438	2019
DNA methylation patterns in bladder tumors of African American patients point to distinct alterations in xenobiotic metabolism. Carcinogenesis\| PubMed ID: 31284295	2019
Exercise restores dysregulated gene expression in a mouse model of arrhythmogenic cardiomyopathy. Cardiovascular research\| PubMed ID: 31350552	2020
Depletion of Endothelial Prolyl Hydroxylase Domain Protein 2 and 3 Promotes Cardiomyocyte Proliferation and Prevents Ventricular Failure Induced by Myocardial Infarction. Circulation\| PubMed ID: 31356139	2019
Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. Oncogene\| PubMed ID: 31383940	2020
The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility†. Biology of reproduction\| PubMed ID: 31403672	2020
The genomic landscape of estrogen receptor α binding sites in mouse mammary gland. PloS one\| PubMed ID: 31408468	2019
Erratum to "Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder" [Eur Urol Focus 2018;4:907-915]. European urology focus\| PubMed ID: 31474581	2019
Loss of the E2 SUMO-conjugating enzyme in oocytes during ovarian folliculogenesis causes infertility in mice. Development (Cambridge, England)\| PubMed ID: 31704792	2019
DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice. Nature communications\| PubMed ID: 31792207	2019
Correction: Expression of ganglioside GD2, reprogram the lipid metabolism and EMT phenotype in bladder cancer. Oncotarget\| PubMed ID: 31827727	2019
MicroRNA-509-3p inhibits cellular migration, invasion, and proliferation, and sensitizes osteosarcoma to cisplatin. Scientific reports\| PubMed ID: 31836741	2019
RNA sequencing-based transcriptome profiling of cardiac tissue implicates novel putative disease mechanisms in FLNC-associated arrhythmogenic cardiomyopathy. International journal of cardiology\| PubMed ID: 31843279	2020
Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture. Circulation\| PubMed ID: 31887080	2020
Long noncoding RNA BHLHE40-AS1 promotes early breast cancer progression through modulating IL-6/STAT3 signaling. Journal of cellular biochemistry\| PubMed ID: 31907974	2020
Metabolic dysregulation in the Wilson's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31924743	2020
Hepatic Tumor Formation in Adult Mice Developmentally Exposed to Organotin. Environmental health perspectives\| PubMed ID: 31939706	2020
A Phase II Study of Cabozantinib and Androgen Ablation in Patients with Hormone-Naïve Metastatic Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 31941830	2020
Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy. Nature communications\| PubMed ID: 32005826	2020
Metabolomic biomarkers are associated with mortality in patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis. Future science OA\| PubMed ID: 32025330	2019
Mechanistic basis and efficacy of targeting the β-catenin-TCF7L2-JMJD6-c-Myc axis to overcome resistance to BET inhibitors. Blood\| PubMed ID: 32068780	2020
Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors. Scientific reports\| PubMed ID: 32071334	2020
DNA hypermethylation during tuberculosis dampens host immune responsiveness. The Journal of clinical investigation\| PubMed ID: 32125282	2020
TAp63-Regulated miRNAs Suppress Cutaneous Squamous Cell Carcinoma through Inhibition of a Network of Cell-Cycle Genes. Cancer research\| PubMed ID: 32156775	2020
Spatiotemporal Regulation of ΔNp63 by TGFβ-Regulated miRNAs Is Essential for Cancer Metastasis. Cancer research\| PubMed ID: 32312834	2020
Discovery, Structure-Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP. Journal of medicinal chemistry\| PubMed ID: 32314924	2020
BCL9/STAT3 regulation of transcriptional enhancer networks promote DCIS progression. NPJ breast cancer\| PubMed ID: 32352029	2020
Estrogen receptor-α expressing neurons in the ventrolateral VMH regulate glucose balance. Nature communications\| PubMed ID: 32358493	2020
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. Cancer cell\| PubMed ID: 32359397	2020
Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood. Nature communications\| PubMed ID: 32385268	2020
Vitamin D actions in neurons require the PI3K pathway for both enhancing insulin signaling and rapid depolarizing effects. The Journal of steroid biochemistry and molecular biology\| PubMed ID: 32408067	2020
BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C-deficient mice. The Journal of clinical investigation\| PubMed ID: 32484798	2020
Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress. Cancers\| PubMed ID: 32599707	2020
Identification of cell type-specific methylation signals in bulk whole genome bisulfite sequencing data. Genome biology\| PubMed ID: 32605651	2020
targets gene networks that promote browning of human and mouse adipocytes. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 32799658	2020
Identification of Genes and Pathways Regulated by Lamin A in Heart. Journal of the American Heart Association\| PubMed ID: 32805188	2020
Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets. BMC biology\| PubMed ID: 32814578	2020
Correction: Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. Oncogene\| PubMed ID: 32820250	2020
Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 32907944	2020
Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic. Redox biology\| PubMed ID: 32961439	2020
Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection. PLoS pathogens\| PubMed ID: 32986782	2020
STAT1 Dissociates Adipose Tissue Inflammation From Insulin Sensitivity in Obesity. Diabetes\| PubMed ID: 32994273	2020
An actin-WHAMM interaction linking SETD2 and autophagy. Biochemical and biophysical research communications\| PubMed ID: 33036756	2021
Pan-cancer analysis reveals TAp63-regulated oncogenic lncRNAs that promote cancer progression through AKT activation. Nature communications\| PubMed ID: 33056990	2020
Integrative transcriptomic analysis for linking acute stress responses to squamous cell carcinoma development. Scientific reports\| PubMed ID: 33057049	2020
Haploinsufficiency of Tmem43 in cardiac myocytes activates the DNA damage response pathway leading to a late-onset senescence-associated pro-fibrotic cardiomyopathy. Cardiovascular research\| PubMed ID: 33070193	2021
Targeting PAK4 Inhibits Ras-Mediated Signaling and Multiple Oncogenic Pathways in High-Risk Rhabdomyosarcoma. Cancer research\| PubMed ID: 33168646	2021
RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer. British journal of cancer\| PubMed ID: 33257837	2021
Isoform-specific Activities of Androgen Receptor and its Splice Variants in Prostate Cancer Cells. Endocrinology\| PubMed ID: 33300995	2021
Coagulopathy in Malnourished Mice Is Sexually Dimorphic and Regulated by Nutrient-Sensing Nuclear Receptors. Hepatology communications\| PubMed ID: 33305154	2020
Hormonal modulation of ESR1 mutant metastasis. Oncogene\| PubMed ID: 33323970	2021
p21-activated kinases as viable therapeutic targets for the treatment of high-risk Ewing sarcoma. Oncogene\| PubMed ID: 33414491	2021
Androgen receptor and its splice variant, AR-V7, differentially induce mRNA splicing in prostate cancer cells. Scientific reports\| PubMed ID: 33446905	2021
Constitutive activation of mitogen-activated protein kinase kinase (MEK1) in ileal enterocytes leads to dysplasia and a predisposition to cancer. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 33470189	2021
Reverse-Phase Protein Array: Technology, Application, Data Processing, and Integration. Journal of biomolecular techniques : JBT\| PubMed ID: 33584151	2021
Altered metabolic and inflammatory transcriptomics after cardiac surgery in neonates with congenital heart disease. Scientific reports\| PubMed ID: 33654130	2021
BET proteolysis targeted chimera-based therapy of novel models of Richter Transformation-diffuse large B-cell lymphoma. Leukemia\| PubMed ID: 33654205	2021
A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 33771853	2021
A cytoskeletal function for PBRM1 reading methylated microtubules. Science advances\| PubMed ID: 33811077	2021
Plasma miRNA Biomarkers in Limited Volume Samples for Detection of Early-stage Pancreatic Cancer. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 33893071	2021
Author Correction: Androgen receptor and its splice variant, AR-V7, differentially induce mRNA splicing in prostate cancer cells. Scientific reports\| PubMed ID: 33976356	2021
Reverse Phase Protein Array Reveals Correlation of Retinoic Acid Metabolism With Cardiomyopathy in Friedreich's Ataxia. Molecular & cellular proteomics : MCP\| PubMed ID: 33991687	2021
Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells. Scientific reports\| PubMed ID: 34002003	2021
Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice. Brain : a journal of neurology\| PubMed ID: 34014281	2021
Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells. Blood cancer journal\| PubMed ID: 34016956	2021
Reverse-Phase Protein Array: Technology, Application, Data Processing, and Integration. Journal of biomolecular techniques : JBT\| PubMed ID: 34025221	2021
Perspectives for systems biology in the management of tuberculosis. European respiratory review : an official journal of the European Respiratory Society\| PubMed ID: 34039674	2021
Effect of sex chromosomes versus hormones in neonatal lung injury. JCI insight\| PubMed ID: 34061778	2021
A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis. Cancer research\| PubMed ID: 34099494	2021
The EP300/TP53 pathway, a suppressor of the Hippo and canonical WNT pathways, is activated in human hearts with arrhythmogenic cardiomyopathy in the absence of overt heart failure. Cardiovascular research\| PubMed ID: 34132777	2022
Early detection of myocardial changes with and without dexrazoxane using serial magnetic resonance imaging in a pre-clinical mouse model. Cardio-oncology (London, England)\| PubMed ID: 34134789	2021
Esomeprazole enhances the effect of ionizing radiation to improve tumor control. Oncotarget\| PubMed ID: 34262645	2021
Effect of substrate stiffness on human intestinal enteroids' infectivity by enteroaggregative Escherichia coli. Acta biomaterialia\| PubMed ID: 34280559	2021
Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulation. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 34288725	2021
High potency STING agonists engage unique myeloid pathways to reverse pancreatic cancer immune privilege. Journal for immunotherapy of cancer\| PubMed ID: 34341132	2021
A machine learning case-control classifier for schizophrenia based on DNA methylation in blood. Translational psychiatry\| PubMed ID: 34341337	2021
A noncoding RNA modulator potentiates phenylalanine metabolism in mice. Science (New York, N.Y.)\| PubMed ID: 34353949	2021
Memory and naïve gamma delta regulatory T-cell gene expression in the first 24-weeks of peanut oral immunotherapy. Clinical immunology (Orlando, Fla.)\| PubMed ID: 34365017	2021
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 34365742	2021
Author Correction: Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells. Scientific reports\| PubMed ID: 34462545	2021
Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. Nature communications\| PubMed ID: 34489478	2021
Inhibition of GATA2 in prostate cancer by a clinically available small molecule. Endocrine-related cancer\| PubMed ID: 34636746	2021
Tuberculosis endotypes to guide stratified host-directed therapy. Med (New York, N.Y.)\| PubMed ID: 34693385	2021
Nuclear S-nitrosylation impacts tissue regeneration in zebrafish. Nature communications\| PubMed ID: 34725362	2021
Single-cell sequencing of rotavirus-infected intestinal epithelium reveals cell-type specific epithelial repair and tuft cell infection. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 34732579	2021
Correction to: Hormonal modulation of ESR1 mutant metastasis. Oncogene\| PubMed ID: 34782721	2022
miR-181a Promotes Multiple Protumorigenic Functions by Targeting TGFβR3. The Journal of investigative dermatology\| PubMed ID: 34890627	2022
Characterization of the COPD alveolar niche using single-cell RNA sequencing. Nature communications\| PubMed ID: 35078977	2022
ΔNp63 regulates a common landscape of enhancer associated genes in non-small cell lung cancer. Nature communications\| PubMed ID: 35105868	2022
Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes. The European respiratory journal\| PubMed ID: 35169026	2022
K-Ras and p53 mouse model with molecular characteristics of human rhabdomyosarcoma and translational applications. Disease models & mechanisms\| PubMed ID: 35174853	2022
ISA101 and nivolumab for HPV-16 cancer: updated clinical efficacy and immune correlates of response. Journal for immunotherapy of cancer\| PubMed ID: 35193933	2022
Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis. Aging\| PubMed ID: 35256539	2022
Author Correction: ΔNp63 regulates a common landscape of enhancer associated genes in non-small cell lung cancer. Nature communications\| PubMed ID: 35338160	2022
Metabolome and microbiome multi-omics integration from a murine lung inflammation model of bronchopulmonary dysplasia. Pediatric research\| PubMed ID: 35338351	2022
Cistrome and transcriptome analysis identifies unique androgen receptor (AR) and AR-V7 splice variant chromatin binding and transcriptional activities. Scientific reports\| PubMed ID: 35354884	2022
Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques. Immunity\| PubMed ID: 35443157	2022
High-throughput profiling of histone post-translational modifications and chromatin modifying proteins by reverse phase protein array. Journal of proteomics\| PubMed ID: 35489683	2022
Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism. Molecular metabolism\| PubMed ID: 35562082	2022
Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer. Cancer medicine\| PubMed ID: 35676822	2023
MAB21L4 Deficiency Drives Squamous Cell Carcinoma via Activation of RET. Cancer research\| PubMed ID: 35705526	2022
The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response. Cancer research\| PubMed ID: 35731919	2022
MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma. Nature communications\| PubMed ID: 35764645	2022
Early Systemic Glycolytic Shift After Aneurysmal Subarachnoid Hemorrhage is Associated with Functional Outcomes. Neurocritical care\| PubMed ID: 35799091	2022
Deletion of the gene in fibroblasts causes senescence-associated dilated cardiomyopathy by activating the double-stranded DNA damage response and induction of senescence-associated secretor... The journal of cardiovascular aging\| PubMed ID: 35891706	2022
Histopathologic and transcriptomic phenotypes of a conditional RANKL transgenic mouse thymus. Cytokine\| PubMed ID: 36099756	2022
Differential co-expression networks of the gut microbiota are associated with depression and anxiety treatment resistance among psychiatric inpatients. Progress in neuro-psychopharmacology & biological psychiatry\| PubMed ID: 36122838	2023
Plasma protein biomarkers for primary graft dysfunction after lung transplantation: a single-center cohort analysis. Scientific reports\| PubMed ID: 36167867	2022
Sex-specific epigenetic development in the mouse hypothalamic arcuate nucleus pinpoints human genomic regions associated with body mass index. Science advances\| PubMed ID: 36170368	2022
The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice. Cell metabolism\| PubMed ID: 36243005	2022
LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination. Oncogene\| PubMed ID: 36348010	2022
Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control. Genome biology\| PubMed ID: 36631879	2023
MicroRNA-mRNA networks are dysregulated in opioid use disorder postmortem brain: Further evidence for opioid-induced neurovascular alterations. Frontiers in psychiatry\| PubMed ID: 36713930	2022
PD-L1 translocation to the plasma membrane enables tumor immune evasion through MIB2 ubiquitination. The Journal of clinical investigation\| PubMed ID: 36719382	2023
Modeling Ewing Sarcoma Lung Metastasis. Current protocols\| PubMed ID: 36799651	2023
Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix. iScience\| PubMed ID: 36824274	2023
A human stem cell-derived neuronal model of morphine exposure reflects brain dysregulation in opioid use disorder: Transcriptomic and epigenetic characterization of postmortem-derived iPSC n... Frontiers in psychiatry\| PubMed ID: 36873219	2023
Patients with Lung Cancer of Different Racial Backgrounds Harbor Distinct Immune Cell Profiles. Cancer research communications\| PubMed ID: 36923308	2022
Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state. British journal of cancer\| PubMed ID: 37012319	2023
TRAF4-mediated nonproteolytic ubiquitination of androgen receptor promotes castration-resistant prostate cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 37155905	2023
Functional genomic analysis of non-canonical DNA regulatory elements of the aryl hydrocarbon receptor. bioRxiv : the preprint server for biology\| PubMed ID: 37205451	2023
MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma. JCI insight\| PubMed ID: 37279073	2023
Infant and Adult Human Intestinal Enteroids are Morphologically and Functionally Distinct. bioRxiv : the preprint server for biology\| PubMed ID: 37292968	2024
TGFβ signaling links early-life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells. Research square\| PubMed ID: 37333266	2023
Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation. Redox biology\| PubMed ID: 37348155	2023
Heritable Traits and Lung Cancer Risk: A Two-Sample Mendelian Randomization Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 37530747	2023
Loss of microRNA-30a and sex-specific effects on the neonatal hyperoxic lung injury. Biology of sex differences\| PubMed ID: 37553579	2023
Multiomic Investigations into Lung Health and Disease. Microorganisms\| PubMed ID: 37630676	2023
TGFβ signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells. Cellular and molecular life sciences : CMLS\| PubMed ID: 37689587	2023
is a synthetic lethal target in -mutant leukemia cells. bioRxiv : the preprint server for biology\| PubMed ID: 37693622	2024
Circadian dysfunction induces NAFLD-related human liver cancer in a mouse model. Journal of hepatology\| PubMed ID: 37890720	2024
Metabolomic Rewiring Promotes Endocrine Therapy Resistance in Breast Cancer. Cancer research\| PubMed ID: 37906431	2024
Human intestinal organoids from Cronkhite-Canada syndrome patients reveal link between serotonin and proliferation. The Journal of clinical investigation\| PubMed ID: 37909332	2023
Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity. Cancer research\| PubMed ID: 38038968	2024
D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder. Developmental cell\| PubMed ID: 38101412	2024
Genome-wide p63-Target Gene Analyses Reveal TAp63/NRF2-Dependent Oxidative Stress Responses. Cancer research communications\| PubMed ID: 38165157	2024
Distinct Amino Acid Profile Characterizes Youth With or at Risk for Type 2 Diabetes. Diabetes\| PubMed ID: 38215171	2024
Temporal dynamics of BMP/Nodal ratio drive tissue-specific gastrulation morphogenesis. bioRxiv : the preprint server for biology\| PubMed ID: 38370754	2024
Identification of an early survival prognostic gene signature for localized osteosarcoma patients. Scientific reports\| PubMed ID: 38538763	2024
The Maternal and Infant Environmental Health Riskscape study of perinatal disparities in greater Houston: rationale, study design and participant profiles. Frontiers in reproductive health\| PubMed ID: 38712340	2024
Altered Extracellular Matrix-Related Pathways Accelerate the Transition from Normal to Pre-Fibroid Myometrium in Black Women. American journal of obstetrics and gynecology\| PubMed ID: 38825029	2024
restrains an oncogenic epigenetic circuit in AT2 cells to prevent ectopic formation of fibrogenic transitional cell intermediates and pulmonary fibrosis. bioRxiv : the preprint server for biology\| PubMed ID: 38826218	2024
is a synthetic-lethal target in -mutant leukemia cells. eLife\| PubMed ID: 38896450	2024
Leveraging Integrated RNA Sequencing to Decipher Adrenomedullin's Protective Mechanisms in Experimental Bronchopulmonary Dysplasia. Genes\| PubMed ID: 38927741	2024