Department of Oncology,
Lombardi Comprehensive Cancer Center,
Department of Medicine
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Concurrent pregnancy retards mammary involution: effects on apoptosis and proliferation of the mammary epithelium after forced weaning of mice.
Biology of reproduction May, 2002 | Pubmed ID: 11967212
Low-volume jet injection for intradermal immunization in rabbits.
BMC biotechnology May, 2002 | Pubmed ID: 12028591
Loss of Stat5a delays mammary cancer progression in a mouse model.
Oncogene Jun, 2002 | Pubmed ID: 12082622
Conditional over-expression of estrogen receptor alpha in a transgenic mouse model.
Transgenic research Aug, 2002 | Pubmed ID: 12212839
The role of prolactin in mammary carcinoma.
Endocrine reviews Feb, 2003 | Pubmed ID: 12588805
Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice.
Development (Cambridge, England) May, 2003 | Pubmed ID: 12642502
Chemoprevention of mammary carcinogenesis in a transgenic mouse model by alpha-difluoromethylornithine (DFMO) in the diet is associated with decreased cyclin D1 activity.
Oncogene May, 2003 | Pubmed ID: 12730671
Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence.
Breast cancer research : BCR , 2003 | Pubmed ID: 12817992
Introduction of estrogen receptor-alpha into the tTA/TAg conditional mouse model precipitates the development of estrogen-responsive mammary adenocarcinoma.
The American journal of pathology Nov, 2003 | Pubmed ID: 14578170
Loss of protein phosphatase 2A expression correlates with phosphorylation of DP-1 and reversal of dysplasia through differentiation in a conditional mouse model of cancer progression.
Cancer research Nov, 2003 | Pubmed ID: 14633688
Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers.
International journal of cancer. Journal international du cancer Feb, 2004 | Pubmed ID: 14696092
Early parity significantly elevates mammary tumor incidence in MMTV-c-myc transgenic mice.
Transgenic research Dec, 2003 | Pubmed ID: 14713205
Explant-cell culture of primary mammary tumors from MMTV-c-Myc transgenic mice.
In vitro cellular & developmental biology. Animal Jan-Feb, 2004 | Pubmed ID: 15180438
Overexpression of an N-terminally truncated isoform of the nuclear receptor coactivator amplified in breast cancer 1 leads to altered proliferation of mammary epithelial cells in transgenic mice.
Molecular endocrinology (Baltimore, Md.) Mar, 2005 | Pubmed ID: 15550471
Deregulated estrogen receptor alpha expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ.
Cancer research Feb, 2005 | Pubmed ID: 15705859
Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1-mutation-related breast cancer.
Oncogene May, 2005 | Pubmed ID: 15750629
PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis.
Oncogene Apr, 2005 | Pubmed ID: 15782144
The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells.
Molecular endocrinology (Baltimore, Md.) Jan, 2006 | Pubmed ID: 16109739
Effect of bilateral oophorectomy on mammary tumor formation in BRCA1 mutant mice.
Oncology reports Nov, 2005 | Pubmed ID: 16211273
Reflectance confocal microscopy for characterization of mammary ductal structures and development of neoplasia in genetically engineered mouse models of breast cancer.
Journal of biomedical optics Sep-Oct, 2005 | Pubmed ID: 16292950
Regulation of progesterone receptor signaling by BRCA1 in mammary cancer.
Nuclear receptor signaling , 2006 | Pubmed ID: 16741564
Methoxychlor induces atresia of antral follicles in ERalpha-overexpressing mice.
Toxicological sciences : an official journal of the Society of Toxicology Sep, 2006 | Pubmed ID: 16787999
What do shifts in indicators of apoptosis indicate about the cancer process?
The Journal of nutrition Oct, 2006 | Pubmed ID: 16988156
Effects of ERalpha overexpression on female reproduction in mice.
Reproductive toxicology (Elmsford, N.Y.) Apr-May, 2007 | Pubmed ID: 17011746
BAX is involved in regulating follicular growth, but is dispensable for follicle atresia in adult mouse ovaries.
Reproduction (Cambridge, England) Jan, 2007 | Pubmed ID: 17244737
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors.
Genome biology , 2007 | Pubmed ID: 17493263
BAX regulates follicular endowment in mice.
Reproduction (Cambridge, England) May, 2007 | Pubmed ID: 17616717
Real-time imaging and characterization of human breast tissue by reflectance confocal microscopy.
Journal of biomedical optics Sep-Oct, 2007 | Pubmed ID: 17994884
Comparison of mouse mammary gland imaging techniques and applications: reflectance confocal microscopy, GFP imaging, and ultrasound.
BMC cancer , 2008 | Pubmed ID: 18215290
The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice.
Cancer research May, 2008 | Pubmed ID: 18483252
Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions.
Endocrine reviews Feb, 2009 | Pubmed ID: 19075184
Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis.
Carcinogenesis Jun, 2010 | Pubmed ID: 20181624
Functional mimicry of the acetylated C-terminal tail of p53 by a SUMO-1 acetylated domain, SAD.
Journal of cellular physiology Nov, 2010 | Pubmed ID: 20458745
Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia.
Cancer research May, 2010 | Pubmed ID: 20466998
Altered AIB1 or AIB1Δ3 expression impacts ERα effects on mammary gland stromal and epithelial content.
Molecular endocrinology (Baltimore, Md.) Apr, 2011 | Pubmed ID: 21292825
BRCA1 deficient mouse models to study pathogenesis and therapy of triple negative breast cancer.
Breast disease , 2010 | Pubmed ID: 21778574
Assessing estrogen signaling aberrations in breast cancer risk using genetically engineered mouse models.
Annals of the New York Academy of Sciences Jul, 2011 | Pubmed ID: 21793850
Comparison of increased aromatase versus ERα in the generation of mammary hyperplasia and cancer.
Cancer research Aug, 2011 | Pubmed ID: 21840986
Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.
Breast cancer research : BCR , 2011 | Pubmed ID: 22018398
The CDK4/6 inhibitor PD0332991 reverses epithelial dysplasia associated with abnormal activation of the cyclin-CDK-Rb pathway.
Cancer prevention research (Philadelphia, Pa.) Jun, 2012 | Pubmed ID: 22508966
Cancer prevention as biomodulation: targeting the initiating stimulus and secondary adaptations.
Annals of the New York Academy of Sciences Oct, 2012 | Pubmed ID: 23050958
Rebecca E. Nakles1,
Sarah L. Millman1,
M. Carla Cabrera1,
Peter Johnson1,2,
Susette Mueller1,2,
Philipp S. Hoppe3,
Timm Schroeder3,
Priscilla A. Furth1,2,4,5
1Department of Oncology, Georgetown University,
2Lombardi Comprehensive Cancer Center, Georgetown University,
3Stem Cell Dynamics, Helmholtz Zentrum München - German Research Center for Environmental Health,
4Department of Medicine, Georgetown University,
5Department of Nanobiomedical Science and WCU Research Center of Nanobiomedical Science, Dankook University
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