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Ian M. Overton

MRC Human Genetics Unit,
MRC IGMM,
MRC Human Genetics Unit, MRC IGMM

University of Edinburgh

BIOGRAPHY

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PUBLICATIONS

A comprehensive collection of chicken cDNAs.

Current biology : CB Nov, 2002 | Pubmed ID: 12445392

Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags.

Genome research Jan, 2005 | Pubmed ID: 15590942

A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms.

Nature Dec, 2004 | Pubmed ID: 15592405

Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.

Journal of immunology (Baltimore, Md. : 1950) Aug, 2005 | Pubmed ID: 16081817

A normalised scale for structural genomics target ranking: the OB-Score.

FEBS letters Jul, 2006 | Pubmed ID: 16808918

The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis.

Journal of molecular biology Jul, 2007 | Pubmed ID: 17559874

ParCrys: a Parzen window density estimation approach to protein crystallization propensity prediction.

Bioinformatics (Oxford, England) Apr, 2008 | Pubmed ID: 18285371

TarO: a target optimisation system for structural biology.

Nucleic acids research Jul, 2008 | Pubmed ID: 18385152

The Scottish Structural Proteomics Facility: targets, methods and outputs.

Journal of structural and functional genomics Jun, 2010 | Pubmed ID: 20419351

XANNpred: neural nets that predict the propensity of a protein to yield diffraction-quality crystals.

Proteins Apr, 2011 | Pubmed ID: 21246630

Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus.

BMC systems biology , 2011 | Pubmed ID: 21569391

Computational approaches to selecting and optimising targets for structural biology.

Methods (San Diego, Calif.) Sep, 2011 | Pubmed ID: 21906678

Addressing statistical biases in nucleotide-derived protein databases for proteogenomic search strategies.

Journal of proteome research Nov, 2012 | Pubmed ID: 23025403

INSTITUTIONS

University of Edinburgh

JOVE ARTICLES

The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers

Fiach C. O'Mahony¹,

Jyoti Nanda¹,

Alexander Laird¹,

Peter Mullen²,

Helen Caldwell³,

Ian M. Overton⁴,

Lel Eory⁴,

Marie O'Donnell^1,5,

Dana Faratian⁶,

Thomas Powles⁷,

David J. Harrison^1,2,

Grant D. Stewart¹

¹Edinburgh Urological Cancer Group, University of Edinburgh,

²School of Medicine, University of St Andrews,

³Division of Pathology, University of Edinburgh,

⁴MRC Human Genetics Unit, MRC IGMM, University of Edinburgh,

⁵Department of Pathology, Western General Hospital,

⁶Breakthrough Breast Cancer Research Unit, University of Edinburgh,

⁷St Bartholomew's Cancer Institute, Experimental Cancer Medicine Centre, Queen Mary University of London

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Ian M. Overton

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University of Edinburgh

The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers

MRC Human Genetics Unit,
MRC IGMM,
MRC Human Genetics Unit, MRC IGMM