Department of Biomedical Engineering
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Gd-DTPA L-cystine bisamide copolymers as novel biodegradable macromolecular contrast agents for MR blood pool imaging.
Pharmaceutical research Jun, 2006 | Pubmed ID: 16729223
Design of novel bioconjugates for targeted drug delivery.
Journal of controlled release : official journal of the Controlled Release Society Jan, 2002 | Pubmed ID: 11772458
Influence of the structure of drug moieties on the in vitro efficacy of HPMA copolymer-geldanamycin derivative conjugates.
Pharmaceutical research Feb, 2002 | Pubmed ID: 11883637
Targeted delivery of doxorubicin by HPMA copolymer-hyaluronan bioconjugates.
Pharmaceutical research Apr, 2002 | Pubmed ID: 12033370
Poly(l-glutamic acid) Gd(III)-DOTA conjugate with a degradable spacer for magnetic resonance imaging.
Bioconjugate chemistry Jul-Aug, 2003 | Pubmed ID: 12862423
Extracellular biodegradable macromolecular gadolinium(III) complexes for MRI.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Jan, 2004 | Pubmed ID: 14705042
PEG-g-poly(GdDTPA-co-L-cystine): a biodegradable macromolecular blood pool contrast agent for MR imaging.
Bioconjugate chemistry Nov-Dec, 2004 | Pubmed ID: 15546211
Contrast-enhanced MRI with new biodegradable macromolecular Gd(III) complexes in tumor-bearing mice.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Apr, 2005 | Pubmed ID: 15799038
Pharmacokinetics and tissue retention of (Gd-DTPA)-cystamine copolymers, a biodegradable macromolecular magnetic resonance imaging contrast agent.
Pharmaceutical research Apr, 2005 | Pubmed ID: 15846467
PEG-g-poly(GdDTPA-co-L-cystine): effect of PEG chain length on in vivo contrast enhancement in MRI.
Biomacromolecules Jul-Aug, 2005 | Pubmed ID: 16004476
Colon-specific 9-aminocamptothecin-HPMA copolymer conjugates containing a 1,6-elimination spacer.
Journal of controlled release : official journal of the Controlled Release Society Jan, 2006 | Pubmed ID: 16290118
Effect of size and charge on pharmacokinetics and in vivo MRI contrast enhancement of biodegradable polydisulfide Gd(III) complexes.
Journal of controlled release : official journal of the Controlled Release Society May, 2006 | Pubmed ID: 16631270
Pharmacokinetics, biodistribution and contrast enhanced MR blood pool imaging of Gd-DTPA cystine copolymers and Gd-DTPA cystine diethyl ester copolymers in a rat model.
Pharmaceutical research Aug, 2006 | Pubmed ID: 16850267
Contrast enhanced MRI-guided photodynamic therapy for site-specific cancer treatment.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Oct, 2006 | Pubmed ID: 16902981
Biodegradable cystamine spacer facilitates the clearance of Gd(III) chelates in poly(glutamic acid) Gd-DO3A conjugates for contrast-enhanced MR imaging.
Magnetic resonance imaging Sep, 2006 | Pubmed ID: 16916710
Noninvasive visualization of in vivo drug delivery of poly(L-glutamic acid) using contrast-enhanced MRI.
Molecular pharmaceutics Sep-Oct, 2006 | Pubmed ID: 17009849
Contrast-enhanced magnetic resonance angiography with biodegradable (Gd-DTPA)-cystamine copolymers: comparison with MS-325 in a swine model.
Molecular pharmaceutics Sep-Oct, 2006 | Pubmed ID: 17009855
Biodistribution and pharmacokinetics of colon-specific HPMA copolymer--9-aminocamptothecin conjugate in mice.
Journal of controlled release : official journal of the Controlled Release Society Feb, 2007 | Pubmed ID: 17150276
Gadolinium(III)-based blood-pool contrast agents for magnetic resonance imaging: status and clinical potential.
Expert opinion on drug delivery Mar, 2007 | Pubmed ID: 17335412
Application of biomedical imaging in drug discovery and development.
Pharmaceutical research Jun, 2007 | Pubmed ID: 17380256
Noninvasive visualization of pharmacokinetics, biodistribution and tumor targeting of poly[N-(2-hydroxypropyl)methacrylamide] in mice using contrast enhanced MRI.
Pharmaceutical research Jun, 2007 | Pubmed ID: 17387601
A novel environment-sensitive biodegradable polydisulfide with protonatable pendants for nucleic acid delivery.
Journal of controlled release : official journal of the Controlled Release Society Jul, 2007 | Pubmed ID: 17582638
Modification of Gd-DTPA cystine copolymers with PEG-1000 optimizes pharmacokinetics and tissue retention for magnetic resonance angiography.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Jul, 2007 | Pubmed ID: 17659618
Polymer platforms for drug delivery and biomedical imaging.
Journal of controlled release : official journal of the Controlled Release Society Oct, 2007 | Pubmed ID: 17662500
Synthesis, characterization, and gene delivery of poly-L-lysine octa(3-aminopropyl)silsesquioxane dendrimers: nanoglobular drug carriers with precisely defined molecular architectures.
Molecular pharmaceutics Sep-Oct, 2007 | Pubmed ID: 17705440
In Vivo evaluation of a PAMAM-cystamine-(Gd-DO3A) conjugate as a biodegradable macromolecular MRI contrast agent.
Experimental biology and medicine (Maywood, N.J.) Sep, 2007 | Pubmed ID: 17720954
Polydisulfide Gd(III) chelates as biodegradable macromolecular magnetic resonance imaging contrast agents.
International journal of nanomedicine , 2006 | Pubmed ID: 17722260
RGD targeted poly(L-glutamic acid)-cystamine-(Gd-DO3A) conjugate for detecting angiogenesis biomarker alpha(v) beta3 integrin with MRT, mapping.
International journal of nanomedicine , 2007 | Pubmed ID: 17722547
Conjugation of poorly absorptive drugs with mucoadhesive polymers for the improvement of oral absorption of drugs.
Journal of controlled release : official journal of the Controlled Release Society Nov, 2007 | Pubmed ID: 17888541
A multifunctional and reversibly polymerizable carrier for efficient siRNA delivery.
Biomaterials Jan, 2008 | Pubmed ID: 17923154
Novel polymerizable surfactants with pH-sensitive amphiphilicity and cell membrane disruption for efficient siRNA delivery.
Bioconjugate chemistry Nov-Dec, 2007 | Pubmed ID: 17939730
[Determination of the lung function by impulse oscillometry in 549 healthy children in Chengdu area].
Zhonghua er ke za zhi. Chinese journal of pediatrics Oct, 2007 | Pubmed ID: 18211755
Gadolinium-conjugated TiO2-DNA oligonucleotide nanoconjugates show prolonged intracellular retention period and T1-weighted contrast enhancement in magnetic resonance images.
Nanomedicine : nanotechnology, biology, and medicine Sep, 2008 | Pubmed ID: 18567541
Contrast-enhanced MRI-guided photodynamic cancer therapy with a pegylated bifunctional polymer conjugate.
Pharmaceutical research Sep, 2008 | Pubmed ID: 18584312
Synthesis and evaluation of globular Gd-DOTA-monoamide conjugates with precisely controlled nanosizes for magnetic resonance angiography.
Biomacromolecules Oct, 2008 | Pubmed ID: 18771313
Structural effect on degradability and in vivo contrast enhancement of polydisulfide Gd(III) complexes as biodegradable macromolecular MRI contrast agents.
Magnetic resonance imaging May, 2009 | Pubmed ID: 18814987
Characterization of tumor angiogenesis with dynamic contrast-enhanced MRI and biodegradable macromolecular contrast agents in mice.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Dec, 2008 | Pubmed ID: 19025902
A peptide targeted contrast agent specific to fibrin-fibronectin complexes for cancer molecular imaging with MRI.
Bioconjugate chemistry Dec, 2008 | Pubmed ID: 19053180
A peptide-targeted delivery system with pH-sensitive amphiphilic cell membrane disruption for efficient receptor-mediated siRNA delivery.
Journal of controlled release : official journal of the Controlled Release Society Mar, 2009 | Pubmed ID: 19135104
Targeted systemic delivery of a therapeutic siRNA with a multifunctional carrier controls tumor proliferation in mice.
Molecular pharmaceutics May-Jun, 2009 | Pubmed ID: 19296675
Targeted intracellular codelivery of chemotherapeutics and nucleic acid with a well-defined dendrimer-based nanoglobular carrier.
Biomaterials Oct, 2009 | Pubmed ID: 19595449
Tumor characterization with dynamic contrast enhanced magnetic resonance imaging and biodegradable macromolecular contrast agents in mice.
Pharmaceutical research Sep, 2009 | Pubmed ID: 19597972
Application of a biodegradable macromolecular contrast agent in dynamic contrast-enhanced MRI for assessing the efficacy of indocyanine green-enhanced photothermal cancer therapy.
Journal of magnetic resonance imaging : JMRI Aug, 2009 | Pubmed ID: 19629979
Rapid simultaneous acquisition of T1 and T2 mapping images using multishot double spin-echo EPI and automated variations of TR and TE (ms-DSEPI-T12).
NMR in biomedicine Jan, 2010 | Pubmed ID: 19777499
Noninvasive evaluation of antiangiogenic effect in a mouse tumor model by DCE-MRI with Gd-DTPA cystamine copolymers.
Molecular pharmaceutics Feb, 2010 | Pubmed ID: 19958031
Molecular imaging of HPMA copolymers: visualizing drug delivery in cell, mouse and man.
Advanced drug delivery reviews Feb, 2010 | Pubmed ID: 20060431
Peptide-targeted Nanoglobular Gd-DOTA monoamide conjugates for magnetic resonance cancer molecular imaging.
Biomacromolecules Mar, 2010 | Pubmed ID: 20131758
Stability and biodistribution of a biodegradable macromolecular MRI contrast agent Gd-DTPA cystamine copolymers (GDCC) in rats.
Pharmaceutical research Jul, 2010 | Pubmed ID: 20393871
An effective targeted nanoglobular manganese(II) chelate conjugate for magnetic resonance molecular imaging of tumor extracellular matrix.
Molecular pharmaceutics Aug, 2010 | Pubmed ID: 20481565
[Findings of electric bronchoscopy in 67 children with recurrent wheezing].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics Jun, 2010 | Pubmed ID: 20540854
New amphiphilic carriers forming pH-sensitive nanoparticles for nucleic acid delivery.
Langmuir : the ACS journal of surfaces and colloids Sep, 2010 | Pubmed ID: 20672851
Synthesis and evaluation of nanoglobule-cystamine-(Gd-DO3A), a biodegradable nanosized magnetic resonance contrast agent for dynamic contrast-enhanced magnetic resonance urography.
International journal of nanomedicine , 2010 | Pubmed ID: 20957222
Polydisulfide Based Biodegradable Macromolecular Magnetic Resonance Imaging Contrast Agents.
Israel journal of chemistry Aug, 2010 | Pubmed ID: 21331318
Synthesis and evaluation of nanoglobular macrocyclic Mn(II) chelate conjugates as non-gadolinium(III) MRI contrast agents.
Bioconjugate chemistry May, 2011 | Pubmed ID: 21473650
Integrin Targeted MR Imaging.
Theranostics , 2011 | Pubmed ID: 21547154
Ocular pharmacokinetic study using Tâ‚ mapping and Gd-chelate- labeled polymers.
Pharmaceutical research Dec, 2011 | Pubmed ID: 21691891
Polydisulfide manganese(II) complexes as non-gadolinium biodegradable macromolecular MRI contrast agents.
Journal of magnetic resonance imaging : JMRI Mar, 2012 | Pubmed ID: 22031457
MR molecular imaging of prostate cancer with a peptide-targeted contrast agent in a mouse orthotopic prostate cancer model.
Pharmaceutical research Apr, 2012 | Pubmed ID: 22139536
Synthesis and evaluation of a peptide targeted small molecular Gd-DOTA monoamide conjugate for MR molecular imaging of prostate cancer.
Bioconjugate chemistry Aug, 2012 | Pubmed ID: 22812444
Single cell molecular recognition of migrating and invading tumor cells using a targeted fluorescent probe to receptor PTPmu.
International journal of cancer. Journal international du cancer Apr, 2013 | Pubmed ID: 22987116
Gadolinium-based contrast agents for magnetic resonance cancer imaging.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology Jan-Feb, 2013 | Pubmed ID: 23047730
Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles.
International journal of nanomedicine , 2012 | Pubmed ID: 23055731
Molecular MRI of liver fibrosis by a peptide-targeted contrast agent in an experimental mouse model.
Investigative radiology Jan, 2013 | Pubmed ID: 23192162
Synthesis and Evaluation of a Targeted Nanoglobular Dual-Modal Imaging Agent for MR Imaging and Image-Guided Surgery of Prostate Cancer.
Pharmaceutical research Mar, 2013 | Pubmed ID: 23471641
Synthesis and evaluation of a polydisulfide with Gd-DOTA monoamide side chains as a biodegradable macromolecular contrast agent for MR blood pool imaging.
Contrast media & molecular imaging May-Jun, 2013 | Pubmed ID: 23606425
Molecular Magnetic Resonance Imaging of Tumors with a PTPµ Targeted Contrast Agent.
Translational oncology Jun, 2013 | Pubmed ID: 23730413
Design and evaluation of new pH-sensitive amphiphilic cationic lipids for siRNA delivery.
Journal of controlled release : official journal of the Controlled Release Society Jun, 2013 | Pubmed ID: 23796431
Peptide targeted tripod macrocyclic Gd(III) chelates for cancer molecular MRI.
Biomaterials Oct, 2013 | Pubmed ID: 23863450
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