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Department of Biomedical Engineering,
Department of Surgery,
Section of Plastic Surgery,
Department of Surgery, Section of Plastic Surgery
Dennis R. Claflin has not added Biography.
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Transgenic mice expressing the myotilin T57I mutation unite the pathology associated with LGMD1A and MFM.
Human molecular genetics Aug, 2006 | Pubmed ID: 16801328
Age-related changes in the structure and function of skeletal muscles.
Clinical and experimental pharmacology & physiology Nov, 2007 | Pubmed ID: 17880359
Direct observation of failing fibers in muscles of dystrophic mice provides mechanistic insight into muscular dystrophy.
American journal of physiology. Cell physiology Feb, 2008 | Pubmed ID: 18171725
Magnitude of sarcomere extension correlates with initial sarcomere length during lengthening of activated single fibers from soleus muscle of rats.
Biophysical journal Aug, 2008 | Pubmed ID: 18469072
Poloxamer 188 reduces the contraction-induced force decline in lumbrical muscles from mdx mice.
American journal of physiology. Cell physiology Jul, 2008 | Pubmed ID: 18495816
Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation.
Journal of applied physiology (Bethesda, Md. : 1985) Jul, 2011 | Pubmed ID: 21565991
Non-uniform distribution of strain during stretch of relaxed skeletal muscle fibers from rat soleus muscle.
Journal of muscle research and cell motility Aug, 2011 | Pubmed ID: 21710358
Effects of high- and low-velocity resistance training on the contractile properties of skeletal muscle fibers from young and older humans.
Journal of applied physiology (Bethesda, Md. : 1985) Oct, 2011 | Pubmed ID: 21799130
Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases.
Nature medicine Mar, 2012 | Pubmed ID: 22344294
Weakness of whole muscles in mice deficient in Cu, Zn superoxide dismutase is not explained by defects at the level of the contractile apparatus.
Age (Dordrecht, Netherlands) Aug, 2013 | Pubmed ID: 22696118
Rotator cuff tear reduces muscle fiber specific force production and induces macrophage accumulation and autophagy.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society Dec, 2012 | Pubmed ID: 22696414
Aging-associated exacerbation in fatty degeneration and infiltration after rotator cuff tear.
Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] Jun, 2013 | Pubmed ID: 23790676
Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice.
Journal of applied physiology (Bethesda, Md. : 1985) Aug, 2014 | Pubmed ID: 24994884
Reduced muscle fiber force production and disrupted myofibril architecture in patients with chronic rotator cuff tears.
Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] Jan, 2015 | Pubmed ID: 25193488
Age affects the contraction-induced mitochondrial redox response in skeletal muscle.
Frontiers in physiology , 2015 | Pubmed ID: 25698975
Mouse forepaw lumbrical muscles are resistant to age-related declines in force production.
Experimental gerontology May, 2015 | Pubmed ID: 25762422
University of Michigan
University of Michigan Medical School
Darcée D. Sloboda1,
Dennis R. Claflin1,2,
James J. Dowling3,
Susan V. Brooks1,4
1Department of Biomedical Engineering, University of Michigan ,
2Department of Surgery, Section of Plastic Surgery, University of Michigan ,
3Departments of Pediatrics and Neurology, University of Michigan ,
4Department of Molecular and Integrative Physiology, University of Michigan
Stuart M. Roche1,
Jonathan P. Gumucio1,2,
Susan V. Brooks2,3,
Christopher L. Mendias1,2,
Dennis R. Claflin3,4
1Department of Orthopaedic Surgery, University of Michigan Medical School,
2Department of Molecular & Integrative Physiology, University of Michigan Medical School,
3Department of Biomedical Engineering, University of Michigan Medical School,
4Department of Surgery, Section of Plastic Surgery, University of Michigan Medical School
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