Lynn W. Enquist

Construction of a self-excisable bacterial artificial chromosome containing the human cytomegalovirus genome and mutagenesis of the diploid TRL/IRL13 gene.

Intravitreal injection of the attenuated pseudorabies virus PRV Bartha results in infection of the hamster suprachiasmatic nucleus only by retrograde transsynaptic transport via autonomic circuits.

Functional integration of adult-born neurons.

A tyrosine-based motif in the cytoplasmic tail of pseudorabies virus glycoprotein B is important for both antibody-induced internalization of viral glycoproteins and efficient cell-to-cell spread.

Physical interaction between envelope glycoproteins E and M of pseudorabies virus and the major tegument protein UL49.

In vivo egress of an alphaherpesvirus from axons.

Break ins and break outs: viral interactions with the cytoskeleton of Mammalian cells.

Pseudorabies virus-induced expression of nitric oxide synthase isoforms.

Brainstem substrates of sympatho-motor circuitry identified using trans-synaptic tracing with pseudorabies virus recombinants.

Recent advances in the use of neurotropic viruses for circuit analysis.

Complete, annotated sequence of the pseudorabies virus genome.

Suprachiasmatic nucleus input to autonomic circuits identified by retrograde transsynaptic transport of pseudorabies virus from the eye.

The pseudorabies virus US3 protein kinase possesses anti-apoptotic activity that protects cells from apoptosis during infection and after treatment with sorbitol or staurosporine.

New developments in tracing neural circuits with herpesviruses.

Herpes simplex virus type 1 glycoprotein e is required for axonal localization of capsid, tegument, and membrane glycoproteins.

UL54-null pseudorabies virus is attenuated in mice but productively infects cells in culture.

Transcriptome signature of virulent and attenuated pseudorabies virus-infected rodent brain.

Alpha-herpesvirus infection induces the formation of nuclear actin filaments.

Local retinal circuits of melanopsin-containing ganglion cells identified by transsynaptic viral tracing.

Targeting of pseudorabies virus structural proteins to axons requires association of the viral Us9 protein with lipid rafts.

Herpesvirus interactions with the host cytoskeleton.

Inputs to serotonergic neurons revealed by conditional viral transneuronal tracing.

John N. Brady (1952-2009): a generous spirit.

Virion-incorporated glycoprotein B mediates transneuronal spread of pseudorabies virus.

Viral genomes are part of the phylogenetic tree of life.

Fluorescence-based monitoring of in vivo neural activity using a circuit-tracing pseudorabies virus.

Recognizing the top 20 peer reviewers for the Journal of Virology.

Pseudorabies virus infection alters neuronal activity and connectivity in vitro.

Calcium imaging of neuronal circuits in vivo using a circuit-tracing pseudorabies virus.

A common neuronal response to alphaherpesvirus infection.

Herpesviruses carrying a Brainbow cassette reveal replication and expression of limited numbers of incoming genomes.

Microdissection of neural networks by conditional reporter expression from a Brainbow herpesvirus.

What's in a Name?

Subversion of the actin cytoskeleton during viral infection.

Herpes simplex virus 1 pUL34 plays a critical role in cell-to-cell spread of virus in addition to its role in virus replication.

A dual infection pseudorabies virus conditional reporter approach to identify projections to collateralized neurons in complex neural circuits.

Select agent publications and the H5N1 flu virus controversy: a JVI perspective.

Policy: Adaptations of avian flu virus are a cause for concern.

Public health and biosecurity. Adaptations of avian flu virus are a cause for concern.

Alphaherpesvirus infection disrupts mitochondrial transport in neurons.

Alphaherpesvirus axon-to-cell spread involves limited virion transmission.

Kinesin-3 mediates axonal sorting and directional transport of alphaherpesvirus particles in neurons.

Efficient retrograde transport of pseudorabies virus within neurons requires local protein synthesis in axons.

Directional spread of alphaherpesviruses in the nervous system.

Role of Us9 phosphorylation in axonal sorting and anterograde transport of pseudorabies virus.

Virus infections in the nervous system.

Imaging the transport dynamics of single alphaherpesvirus particles in intact peripheral nervous system explants from infected mice.

Glycoproteins gE and gI Are Required for Efficient KIF1A-Dependent Anterograde Axonal Transport of Alphaherpesvirus Particles in Neurons.

Fast GCaMPs for improved tracking of neuronal activity.