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Longgang District Maternity & Child Healthcare Hospital of Shenzhen City

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Isolation of Umbilical Cord-Derived Mesenchymal Stem Cells with High Yields and Low Damage
Mingyuan Xu 1,2, Jiasen Xu 2, Danling Cheng 3,4, Xiaoni Chen 2, Shan Lin 2, Xinlei Si 2, Fangfang Guo 3,4, Di Wu 2, Fenfang Wu 2
1Beijing University of Chinese Medicine, 2Department of Central Laboratory, Shenzhen Hospital, Beijing University of Chinese Medicine, 3Obstetrical Department, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City, 4Longgang Maternity and Child Institute of Shantou University, Medical College

This study presents a unique blunt dissection procedure to preserve the integrity of Wharton's jelly (WJ), resulting in less damaged WJ and a greater quantity and viability of the harvested mesenchymal stem cells (MSCs). The method demonstrates superior yield and proliferative ability compared to conventional sharp dissection methods.

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