Models of Bone MetastasisJ. Preston Campbell 1,2, Alyssa R. Merkel 2,3,4, S. Kathryn Masood-Campbell 2,4, Florent Elefteriou 1,2,4,5, Julie A. Sterling 2,3,4,5
1Department of Pharmacology, Vanderbilt University, 2Vanderbilt Center for Bone Biology, Vanderbilt University, 3Department of Veterans Affairs, Tennessee Valley Healthcare System (VISN 9), 4Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University, 5Department of Cancer Biology, Vanderbilt University
Animal models are frequently utilized to study cancer metastasis to bone. In this protocol we will describe two common methods of tumor inoculation for bone metastasis studies and briefly describe some of the analyses utilized to monitor and quantify these models.
