Reverse Genetic Approach to Identify Regulators of Pigmentation using ZebrafishBabita Sharma *1,2, Yogaspoorthi J. Subramaniam *1,2, Desingu Ayyappa Raja 1,2,3, Ayush Aggarwal 1,2, Sridhar Sivasubbu 1, Vivek T. Natarajan 1,2
1CSIR-Institute of Genomics and Integrative Biology, 2Academy of Scientific and Innovative Research, 3Division of Biology and Biological Engineering, California Institute of Technology
Regulators of melanocyte functions govern visible differences in the pigmentation outcome. Deciphering the molecular function of the candidate pigmentation gene poses a challenge. Herein, we demonstrate the use of a zebrafish model system to identify candidates and classify them into regulators of melanin content and melanocyte number.
