Morgagni-Pierantoni Hospital
2 ARTICLES PUBLISHED IN JoVE
Cancer Research
Cell-Free DNA Integrity Analysis in Urine Samples
Valentina Casadio 1, Samanta Salvi 1, Filippo Martignano 1, Roberta Gunelli 2, Sara Ravaioli 1, Daniele Calistri 1
1Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 2Department of Urology, Morgagni-Pierantoni Hospital
A method for analyzing DNA integrity in the cell-free supernatant fraction of urine samples is proposed. The method is suitable for early detection of urological malignancies and has proven accurate for the early diagnosis of bladder cancer.
Cancer Research
Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Alessandro De Vita 1, Laura Mercatali 1, Giacomo Miserocchi 1, Chiara Liverani 1, Chiara Spadazzi 1, Federica Recine 1, Alberto Bongiovanni 1, Federica Pieri 2, Davide Cavaliere 3, Valentina Fausti 1, Dino Amadori 1, Toni Ibrahim 1
1Osteoncology and Rare Tumors Center, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 2Pathology Unit, Morgagni-Pierantoni Hospital, 3Unit of Surgery and Advanced Oncologic Therapies, Morgagni-Pierantoni Hospital
The following protocol focuses on the establishment of a primary culture of patient-derived soft tissue sarcoma (STS). This model could help us to better understand the molecular background and pharmacological profile of these rare malignancies and could represent a starting point for further research aimed at improving STS management.
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